{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:00:53Z","timestamp":1768266053336,"version":"3.49.0"},"reference-count":30,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Medicine and Pharmacy Carol Davila"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Background: Cardiac resynchronization therapy (CRT) is an essential treatment for patients with symptomatic heart failure and ventricular conduction abnormalities. Low-ejection-fraction (EF) cardiomyopathy often involves a wide QRS complex displaying a left bundle branch block (LBBB) morphology and markedly delayed activation of the LV lateral wall. Following CRT, patients with heart failure and LBBB have better outcomes and quality-of-life improvements. Various electrocardiographic and clinical parameters are thought to be able to predict this improvement. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a reliable tool for measuring these patients\u2019 quality of life. Methods: This is an observational prospective study featuring over 69 individuals diagnosed with cardiac failure and dilatative cardiomyopathy with low-EF and major LBBB. This study analyzed the correlations between patient outcomes and demographic, clinical, and electrocardiographic parameters. Results: Following the analysis, we observed correlations between the QRS area, intraprocedural systolic blood pressure, Q-LV interval, the R-wave amplitude in the right precordial leads and the CRT outcomes indicated by the KCCQ score. Conclusions: The parameters found and their correlation with the KCCQ score show how CRT therapy impacts patients\u2019 quality of life, symptom burden, and functional status.<\/jats:p>","DOI":"10.3390\/life14121564","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T10:19:42Z","timestamp":1732789182000},"page":"1564","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Relationship Between the Kansas City Cardiomyopathy Questionnaire and Electrocardiographic Parameters in Predicting Outcomes After Cardiac Resynchronization Therapy"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5500-1620","authenticated-orcid":false,"given":"Andrei-Mihnea","family":"Rosu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Prof. Dr. Agrippa Ionescu Emergency Hospital, Balotesti, 077015 Ilfov, Romania"},{"name":"Doctoral School, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luminita-Florentina","family":"Tomescu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Prof. Dr. Agrippa Ionescu Emergency Hospital, Balotesti, 077015 Ilfov, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1225-097X","authenticated-orcid":false,"given":"Theodor-Georgian","family":"Badea","sequence":"additional","affiliation":[{"name":"Doctoral School, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Radiology, Prof. Dr. Agrippa Ionescu Emergency Hospital, Balotesti, 077015 Ilfov, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel-Stefan","family":"Radu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Prof. Dr. Agrippa Ionescu Emergency Hospital, Balotesti, 077015 Ilfov, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreea-Liana","family":"Rosu","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, BBraun, 013714 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2251-0725","authenticated-orcid":false,"given":"Lavinia-Nicoleta","family":"Brezeanu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care I, Fundeni Clinical Institute, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria-Daniela","family":"Tanasescu","sequence":"additional","affiliation":[{"name":"Department of Semiology, Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2687-2611","authenticated-orcid":false,"given":"Sebastian","family":"Isac","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care I, Fundeni Clinical Institute, 022328 Bucharest, Romania"},{"name":"Department of Physiology, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teodora","family":"Isac","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oana-Andreea","family":"Popa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Prof. Dr. Agrippa Ionescu Emergency Hospital, Balotesti, 077015 Ilfov, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5933-8549","authenticated-orcid":false,"given":"Crina-Julieta","family":"Sinescu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bagdasar-Arseni Emergency Hospital, Carol Davila University of Medicine and Pharmacy, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jjcc.2021.10.021","article-title":"Cardiac resynchronization therapy: Current status and near-future prospects","volume":"79","author":"Nakai","year":"2022","journal-title":"J. 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