{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T22:28:09Z","timestamp":1768343289200,"version":"3.49.0"},"reference-count":56,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Medicine and Pharmacy Carol Davila through the institutional program Publish not Perish"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with the compression or invasion of adjacent structures. Abdominal localization is most commonly reported, although there are reports of mediastinal desmoid tumors. We present the case of a 6-day male patient with a mediastinal desmoid tumor that led to severe aortic coarctation with hemodynamic instability. The tumor also compressed the left pulmonary artery and obstructed the left main bronchus. The initial management consisted of successful emergency surgery with partial resection of the tumor mass and coarctation repair. In the postoperative setting, the patient evolved with severe respiratory dysfunction which was managed with tracheostomy, allowing weaning the child from the mechanical ventilation one month after surgery, along with chemotherapy. We also review the literature, focusing on the management of desmoid tumors.<\/jats:p>","DOI":"10.3390\/life15010123","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T10:27:58Z","timestamp":1737109678000},"page":"123","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"Irina Maria","family":"Margarint","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammam","family":"Youssef","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Emergency Clinical Hospital for Children \u201cMaria Sk\u0142odowska Curie\u201d, 077120 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Filip","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana-Mihaela","family":"Bizubac","sequence":"additional","affiliation":[{"name":"\u201cMarie S. Curie Children\u2019s Emergency Hospital\u201d Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1734-4921","authenticated-orcid":false,"given":"Alexandru","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Emergency Clinical Hospital for Children \u201cMaria Sk\u0142odowska Curie\u201d, 077120 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iulian","family":"Rotaru","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Emergency Clinical Hospital for Children \u201cMaria Sk\u0142odowska Curie\u201d, 077120 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olguta","family":"Untaru","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Emergency Clinical Hospital for Children \u201cMaria Sk\u0142odowska Curie\u201d, 077120 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Manolache","sequence":"additional","affiliation":[{"name":"\u201cMarie S. Curie Children\u2019s Emergency Hospital\u201d Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9069-2722","authenticated-orcid":false,"given":"Vlad Anton","family":"Iliescu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9512-2673","authenticated-orcid":false,"given":"Radu","family":"Vladareanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/0002-9610(86)90076-0","article-title":"The desmoid syndrome. 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