{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:08:43Z","timestamp":1779257323861,"version":"3.51.4"},"reference-count":21,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005322","name":"Recep Tayyip Erdogan University Development Foundation","doi-asserted-by":"publisher","award":["02024012003193"],"award-info":[{"award-number":["02024012003193"]}],"id":[{"id":"10.13039\/501100005322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Purpose: This study aimed to evaluate the relationship between preoperative ocular biometric parameters and intraocular pressure (IOP) reduction after phacoemulsification in non-glaucomatous eyes. Methods: The charts of non-glaucomatous patients who underwent phacoemulsification and lens implantation were retrospectively reviewed. IOP was measured preoperatively and 3 months after surgery. The change in IOP and its relation to ocular biometric parameters, including anterior chamber depth (ACD), lens thickness (LT), axial length (AL), and central corneal thickness (CCT), measured preoperatively by LENSTAR LS 900 (Haag-Streit, Inc., Koeniz, Switzerland), were evaluated. The impact of each parameter on the alteration in IOP was assessed using a regression model. Results: The analysis included 171 eyes of 145 patients, with a mean age of 68.7 \u00b1 11 years. The average IOP reduction following cataract surgery was 3.0 \u00b1 2.9 mmHg, decreasing from a preoperative mean of 16.3 \u00b1 2.8 mmHg. The amount of IOP reduction showed statistically significant correlations with preoperative ocular parameters. Eyes with shallower anterior chambers demonstrated a greater IOP reduction (r = \u22120.307, p = 0.034), as did those with thicker lenses (r = 0.383, p = 0.026). Multivariate regression analysis further confirmed that higher preoperative IOP, shallower ACD, and thicker lenses were independently associated with greater postoperative IOP decreases (p &lt; 0.001). AL and CCT did not exhibit significant associations with IOP reduction. Conclusions: The amount of IOP reduction is significantly greater in eyes with higher preoperative IOP, thicker lenses, and shallower anterior chamber after cataract surgery in non-glaucomatous eyes.<\/jats:p>","DOI":"10.3390\/life15030381","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T06:45:42Z","timestamp":1740725142000},"page":"381","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Preoperative Ocular Biometric Parameters as Predictors of Intraocular Pressure Reduction After Phacoemulsification Cataract Surgery in Non-Glaucomatous Eyes"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3050-0714","authenticated-orcid":false,"given":"Feyzahan","family":"Uzun","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7343-8757","authenticated-orcid":false,"given":"H\u00fcseyin","family":"Findik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6523-7648","authenticated-orcid":false,"given":"Muhammet","family":"Kaim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, 53100 Rize, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ogla.2020.06.002","article-title":"Intraocular Pressure Changes after Cataract Surgery in Patients with and without Glaucoma: An Informatics-Based Approach","volume":"3","author":"Wang","year":"2020","journal-title":"Ophthalmol. Glaucoma"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1007\/s40123-022-00639-z","article-title":"The Treatment of Primary Angle-Closure Glaucoma with Cataract: A Systematic Review and Meta-Analysis of Randomized Controlled Trails","volume":"12","author":"Xie","year":"2023","journal-title":"Ophthalmol. Ther."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/S0140-6736(16)30956-4","article-title":"Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): A randomised controlled trial","volume":"388","author":"Burr","year":"2016","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.preteyeres.2018.01.003","article-title":"Cataract, phacoemulsification and intraocular pressure: Is the anterior segment anatomy the missing piece of the puzzle?","volume":"64","author":"Lin","year":"2018","journal-title":"Prog. Retin. Eye Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"7807","DOI":"10.1167\/iovs.15-17926","article-title":"Lens Position Parameters as Predictors of Intraocular Pressure Reduction After Cataract Surgery in Nonglaucomatous Patients with Open Angles","volume":"56","author":"Hsu","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/02713683.2019.1580375","article-title":"How to Predict Intraocular Pressure Reduction after Cataract Surgery? A Prospective Study","volume":"44","author":"Perez","year":"2019","journal-title":"Curr. Eye Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1167\/iovs.16-19384","article-title":"Lens Position Parameters as Predictors of Intraocular Pressure Reduction After Cataract Surgery in Glaucomatous Versus Nonglaucomatous Eyes","volume":"57","author":"Coh","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1136\/bjophthalmol-2015-306713","article-title":"Effect of bilateral sequential cataract extraction on intraocular pressure in non-glaucomatous Asian eyes","volume":"100","author":"Ngo","year":"2016","journal-title":"Br. J. Ophthalmol."},{"key":"ref_9","first-page":"1960","article-title":"Intraocular pressure-lowering effect of cataract surgery: Predictive patient factors and timing of IOP-lowering effect","volume":"60","author":"Ruppert","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"143","DOI":"10.18410\/jebmh\/2020\/30","article-title":"Effect of Cataract Surgery on Intraocular Pressure in Non-Glaucomatous Patients-A Prospective Study","volume":"7","author":"Majumdar","year":"2020","journal-title":"J. Evid. Based Med. Healthc."},{"key":"ref_11","first-page":"e51500","article-title":"Anterior Chamber Biometric Parameters Associated with Intraocular Pressure Reduction After Phacoemulsification in Non-Glaucomatous Eyes with Open Angles","volume":"16","author":"Sarkar","year":"2024","journal-title":"Cureus"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Marki\u0107, B., Mavija, M., Smoljanovi\u0107-Sko\u010di\u0107, S., Popovi\u0107, M.T., and Burgi\u0107, S.S. (2022). Predictors of intraocular pressure change after cataract surgery in patients with pseudoexfoliation glaucoma and in nonglaucomatous patients. Vojnosanit. Pregl., 79.","DOI":"10.2298\/VSP200421081M"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s10792-016-0230-7","article-title":"Effect of intraoperative factors on IOP reduction after phacoemulsification","volume":"37","author":"DeVience","year":"2017","journal-title":"Int. Ophthalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1001\/archophthalmol.2011.272","article-title":"Anterior Chamber Depth, Iridocorneal Angle Width, and Intraocular Pressure Changes After Phacoemulsification: Narrow vs. Open Iridocorneal Angles","volume":"129","author":"Huang","year":"2011","journal-title":"Arch. Ophthalmol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1167\/iovs.16-21045","article-title":"Factors Associated with Corneal Deformation Responses Measured with a Dynamic Scheimpflug Analyzer","volume":"58","author":"Miki","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000377635","article-title":"Cataract Surgery and Intraocular Pressure","volume":"53","author":"Melancia","year":"2015","journal-title":"Ophthalmic Res."},{"key":"ref_17","first-page":"167","article-title":"Effects of Cataract Surgery on Intraocular Pressure in Patients with and without Glaucoma","volume":"43","year":"2013","journal-title":"Turk. J. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/S0161-6420(00)00007-5","article-title":"Changes in anterior chamber angle width and depth after intraocular lens implantation in eyes with glaucoma","volume":"107","author":"Hayashi","year":"2000","journal-title":"Ophthalmology"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/s12886-019-1157-3","article-title":"Long term effect of phacoemulsification on intraocular pressure in patients with medically controlled primary open-angle glaucoma","volume":"19","author":"Majstruk","year":"2019","journal-title":"BMC Ophthalmol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1167\/iovs.02-0631","article-title":"Ultrasound activates the TM ELAM-1\/IL-1\/NF-kappaB response: A potential mechanism for intraocular pressure reduction after phacoemulsification","volume":"44","author":"Wang","year":"2003","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_21","unstructured":"Uzun, F., and Findik, H. (2018, January 22\u201326). Anterior segment parameters as predictors of intraocular pressure reduction after phacoemulsification cataract surgery in non-glaucomatous eyes. Proceedings of the 36th Congress of European Society of Cataract and Refractive Surgeons (ESCRS), Vienna, Austria. Available online: https:\/\/legacy.escrs.org\/vienna2018\/programme\/free-papers-details.asp?id=30549&day=0."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/3\/381\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:44:07Z","timestamp":1760028247000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/3\/381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,28]]},"references-count":21,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["life15030381"],"URL":"https:\/\/doi.org\/10.3390\/life15030381","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,28]]}}}