{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T03:45:13Z","timestamp":1766720713704,"version":"build-2065373602"},"reference-count":43,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Functional endoscopic sinus Surgery (FESS) is a form of safe and effective management for chronic rhinosinusitis. Nevertheless, although FESS is minimally invasive, it poses a risk of rare orbital complications. This study aims to investigate the variations in the medial maxillary wall relative to the medial orbital wall, as depicted on computed tomography (CT) scans. We retrospectively included CT scans of the sinuses between November 2022 and April 2023. To maintain consistency, we used the coronal image that delineated the anterior ethmoidal foramen. The attachment site of the inferior turbinate to the medial maxillary wall was categorized into three classes according to its position relative to the inferomedial orbital strut. Class I indicates that the site of attachment is located within 2 mm, either medially or laterally. Class II indicates that it has been medially displaced by more than 2 mm, whereas Class III indicates that it has been laterally displaced by more than 2 mm. We enrolled 183 patients, yielding a total of 363 sides. Classes I, II, and III account for 55.4%, 41.3%, and 3.3% of the cases, respectively. A significant correlation exists between the classification and the dimensions and volume of the maxillary sinus (p &lt; 0.001). The logistic regression model indicates a significant negative correlation between the width of the maxillary sinus and risk classification (p &lt; 0.001), implying a protective effect with increasing width. Knowledge of the variations in the medial wall of the maxillary sinus relative to the medial orbital wall is essential for guidance toward the optimal endoscopic approach, and it demonstrates relevance to risk stratification.<\/jats:p>","DOI":"10.3390\/life15030453","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T06:53:00Z","timestamp":1741848780000},"page":"453","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["CT Analysis of Variations in the Medial Maxillary Wall Relative to the Medial Orbital Wall: Implications for Surgical Risk Stratification from an Endoscopic Perspective"],"prefix":"10.3390","volume":"15","author":[{"given":"Humaid","family":"Alhumaid","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, College of Medicine, Qassim University, Buraydah 52571, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0498-2932","authenticated-orcid":false,"given":"Abdulrahman","family":"Alsowinea","sequence":"additional","affiliation":[{"name":"College of Medicine, Qassim University, Buraydah 52571, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Alamer","sequence":"additional","affiliation":[{"name":"Department of Radiology, College of Medicine, Qassim University, Buraydah 52571, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.wjorl.2016.12.001","article-title":"Thirty years of endoscopic sinus surgery: What have we learned?","volume":"3","author":"Tajudeen","year":"2017","journal-title":"World J. Otorhinolaryngol.-Head Neck Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5s","DOI":"10.1177\/01455613241287280","article-title":"Functional Endoscopic Sinus Surgery: Key Points for Safer Surgery","volume":"103","author":"Kar","year":"2024","journal-title":"Ear Nose Throat J."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Abdulla, M., Refaat, O., Alahmer, M., Yehia, A., Abdelsalam, H., Abdelaal, K., and Shams Eldin, M. (2024). Prelacrimal Recess Approach in Unilateral Maxillary Sinus Lesions: What Is the Impact and Efficacy?. Medicina, 60.","DOI":"10.3390\/medicina60020222"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/lary.20777","article-title":"Ambulatory sinus and nasal surgery in the United States: Demographics and perioperative outcomes","volume":"120","author":"Bhattacharyya","year":"2010","journal-title":"Laryngoscope"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1097\/MLG.0b013e31804b1a90","article-title":"Important clinical symptoms in patients undergoing functional endoscopic sinus surgery for chronic rhinosinusitis","volume":"117","author":"Ling","year":"2007","journal-title":"Laryngoscope"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1365-2273.1994.tb01225.x","article-title":"Major complications of functional endoscopic sinus surgery","volume":"19","author":"Cumberworth","year":"1994","journal-title":"Clin. Otolaryngol. Allied Sci."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Vinciguerra, A., Dohin, I., Daloiso, A., Boaria, F., Marc, M., Verillaud, B., Chatelet, F., and Herman, P. (2024). Iatrogenic Cerebrospinal Fluid Leak in Endoscopic Sinus Surgery: Topographical Map and Influence of Skull Base Asymmetry. J. Pers. Med., 14.","DOI":"10.3390\/jpm14030226"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1002\/lary.24401","article-title":"Complications of primary and revision functional endoscopic sinus surgery for chronic rhinosinusitis","volume":"124","author":"Krings","year":"2014","journal-title":"Laryngoscope"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.bjorl.2016.04.006","article-title":"Ophthalmic complications of endoscopic sinus surgery","volume":"83","author":"Burduk","year":"2017","journal-title":"Braz. J. Otorhinolaryngol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.crad.2005.03.005","article-title":"Orbital complications of functional endoscopic sinus surgery: MR and CT findings","volume":"60","author":"Bhatti","year":"2005","journal-title":"Clin. Radiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e580","DOI":"10.1097\/SCS.0000000000008557","article-title":"Analysis of the Lamina Papyracea Dehiscence Based on Computed Tomography Findings","volume":"33","author":"Xu","year":"2022","journal-title":"J. Craniofacial Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3649","DOI":"10.1007\/s00405-024-08538-8","article-title":"Evaluation of lamina papyracea dehiscence with paranasal computed tomography","volume":"281","author":"Deniz","year":"2024","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_13","first-page":"522","article-title":"The relationship between ethmoidal foramina and orbital fat herniation","volume":"52","author":"Kaya","year":"2022","journal-title":"Turk. J. Med. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1097\/00005537-200112000-00008","article-title":"A computer-assisted anatomical study of the nasofrontal region","volume":"111","author":"Landsberg","year":"2001","journal-title":"Laryngoscope"},{"key":"ref_15","unstructured":"Kaluskar, S.K., and Sachdeva, S. (2024, December 15). Complications in Endoscopic Sinus Surgery: Diagnosis, Prevention and Management. Available online: https:\/\/cir.nii.ac.jp\/crid\/1130282273228666112."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/00005537-199803000-00020","article-title":"Interpretation of anatomic variations of computed tomography scans of the sinuses: A surgeon\u2019s perspective","volume":"108","author":"Meyers","year":"1998","journal-title":"Laryngoscope"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/alr.21450","article-title":"Variations of lamina papyracea position from the endoscopic view: A retrospective computed tomography analysis","volume":"5","author":"Herzallah","year":"2015","journal-title":"Int. Forum Allergy Rhinol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.anl.2017.09.006","article-title":"Lamina papyracea position in patients with nasal polypi: A computed tomography analysis","volume":"45","author":"Khazbak","year":"2018","journal-title":"Auris Nasus Larynx"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.bjorl.2018.04.008","article-title":"Computed tomography based analysis of the lamina papyracea variations and morphology of the orbit concerning endoscopic surgical approaches","volume":"85","year":"2019","journal-title":"Braz. J. Otorhinolaryngol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jasi.2014.04.007","article-title":"Measurements of maxillary sinus volume and dimensions by computed tomography scan for gender determination","volume":"63","author":"Sharma","year":"2014","journal-title":"J. Anat. Soc. India"},{"key":"ref_21","first-page":"183","article-title":"Staging in rhinosinusitus","volume":"31","author":"Lund","year":"1993","journal-title":"Rhinology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1177\/00034894041130S506","article-title":"Imaging for staging of rhinosinusitis","volume":"193","author":"Zinreich","year":"2004","journal-title":"Ann. Otol. Rhinol. Laryngol. Suppl."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1148\/radiol.2016152230","article-title":"The Preoperative Sinus CT: Avoiding a \u201cCLOSE\u201d Call with Surgical Complications","volume":"281","author":"Hamelin","year":"2016","journal-title":"Radiology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s12070-010-0047-z","article-title":"The location of maxillary sinus ostium and its clinical application","volume":"62","author":"Prasanna","year":"2010","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Do, J., and Han, J.J. (2022). Anatomical Characteristics of the Accessory Maxillary Ostium in Three-Dimensional Analysis. Medicina, 58.","DOI":"10.3390\/medicina58091243"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1177\/0194599816630722","article-title":"Orbital Decompression in the Endoscopic Age: The Modified Inferomedial Orbital Strut","volume":"154","author":"Yao","year":"2016","journal-title":"Otolaryngol.-Head Neck Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00002341-200209000-00007","article-title":"The inferomedial orbital strut: An anatomic and radiographic study","volume":"18","author":"Kim","year":"2002","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Someda, S.K., Miyazaki, H., Kakizaki, H., and Takahashi, Y. (2024). Clinical Significance of the Inferomedial Orbital Strut in Orbital Blowout Fractures: Incidence of Symptomatic Diplopia in a Fractured vs. Intact Strut. J. Clin. Med., 13.","DOI":"10.3390\/jcm13133682"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/alr.21079","article-title":"Beyond the \u201ccentral sinus\u201d: Radiographic findings in patients undergoing revision functional endoscopic sinus surgery","volume":"3","author":"Gore","year":"2013","journal-title":"Int. Forum Allergy Rhinol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Khalil, H.S., Eweiss, A.Z., and Clifton, N. (2011). Radiological findings in patients undergoing revision endoscopic sinus surgery: A retrospective case series study. BMC Ear Nose Throat Disord., 11.","DOI":"10.1186\/1472-6815-11-4"},{"key":"ref_31","first-page":"589","article-title":"Effect of lamina papyracea ingression on orbito-ocular complications after functional endoscopic sinus surgery","volume":"51","author":"Wang","year":"2016","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0039-6257(03)00055-9","article-title":"Ophthalmic complications of endoscopic sinus surgery","volume":"48","author":"Bhatti","year":"2003","journal-title":"Surv. Ophthalmol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1017\/S0022215121004485","article-title":"Functional endoscopic sinus surgery outcome in chronic rhinosinusitis patients with hypoplastic maxillary sinus","volume":"136","author":"Zubidi","year":"2022","journal-title":"J. Laryngol. Otol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1001\/archoto.2010.75","article-title":"Factors for maxillary sinus volume and craniofacial anatomical features in adults with chronic rhinosinusitis","volume":"136","author":"Cho","year":"2010","journal-title":"Arch. Otolaryngol.-Head Neck Surg."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Kedar, E., Koren, I., Medlej, B., and Hershkovitz, I. (2023). The Associations between the Maxillary Sinus Volume, Infraorbital Ethmoid Cells, and the Infraorbital Canal: A CT-Based Study. Diagnostics, 13.","DOI":"10.3390\/diagnostics13233593"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1002\/lary.21446","article-title":"Complications in endoscopic sinus surgery for chronic rhinosinusitis: A 25-year experience","volume":"121","author":"Stankiewicz","year":"2011","journal-title":"Laryngoscope"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jcma.2015.11.001","article-title":"Multiple analyses of factors related to complications in endoscopic sinus surgery","volume":"79","author":"Chou","year":"2016","journal-title":"J. Chin. Med. Assoc."},{"key":"ref_38","first-page":"46","article-title":"Age and gender assessment through three-dimensional morphometric analysis of maxillary sinus using magnetic resonance imaging","volume":"9","author":"Rani","year":"2017","journal-title":"J. Forensic Dent. Sci."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Christoloukas, N., Mitsea, A., Rontogianni, A., and Angelopoulos, C. (2023). Gender Determination Based on CBCT Maxillary Sinus Analysis: A Systematic Review. Diagnostics, 13.","DOI":"10.3390\/diagnostics13233536"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Lee, Y.H., Cho, W.K., Kim, D.H., and Kim, J.H. (2024). The impact of maxillary dimensions on determining surgical approach of fungal ball in the maxillary sinus. Sci. Rep., 14.","DOI":"10.1038\/s41598-024-58726-z"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Andrianakis, A., Moser, U., Wolf, A., Kiss, P., Holzmeister, C., Andrianakis, D., and Tomazic, P.V. (2021). Gender-Specific Differences in Feasibility of Pre-Lacrimal Window Approach. Sci. Rep., 11.","DOI":"10.1038\/s41598-021-87447-w"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s12070-009-0059-8","article-title":"CT scan evaluation of the anatomical variations of the ostiomeatal complex","volume":"61","author":"Wani","year":"2009","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"e34510","DOI":"10.1097\/MD.0000000000034510","article-title":"Anatomical variations and abnormalities of the maxillary region and clinical implications: A systematic review and metaanalysis","volume":"102","author":"Medina","year":"2023","journal-title":"Medicine"}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/3\/453\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:52:55Z","timestamp":1760028775000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/3\/453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":43,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["life15030453"],"URL":"https:\/\/doi.org\/10.3390\/life15030453","relation":{},"ISSN":["2075-1729"],"issn-type":[{"type":"electronic","value":"2075-1729"}],"subject":[],"published":{"date-parts":[[2025,3,13]]}}}