{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T21:19:44Z","timestamp":1782422384983,"version":"3.54.5"},"reference-count":139,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>This study aimed to comprehensively review surgical interventions for ocular surface diseases (OSDs), including dry eye syndrome (DES), exposure keratopathy, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and ocular graft versus host disease (oGVHD), and to highlight the indications, contraindications, outcomes, and complications of various oculoplastic procedures used in their management. A narrative review was performed based on expert-guided selection of relevant studies retrieved from PubMed, Scopus, and Web of Science. Relevant keywords included \u201cocular surface disease\u201d, \u201cdry eye syndrome\u201d, \u201cexposure keratopathy\u201d, \u201cthyroid eye disease (TED)\u201d, \u201cneurotrophic keratopathy (NK)\u201d, \u201cStevens-Johnson syndrome\u201d, \u201ctoxic epidermal necrolysis\u201d, \u201cpunctal occlusion\u201d, \u201ctarsorrhaphy\u201d, \u201cbotulinum toxin\u201d, \u201ceyelid loading\u201d, \u201cretractor weakening\u201d, \u201ccorneal neurotization (CN)\u201d, \u201camniotic membrane transplantation (AMT)\u201d, \u201cconjunctival flap\u201d, \u201cocular graft versus host disease\u201d, and \u201csalivary gland transplantation (SGT)\u201d. Studies addressing surgical approaches for OSDs were included. In conclusion, surgical options for OSDs offer significant benefits when non-invasive treatments fail. Surgical techniques such as punctal occlusion, eyelid fissure narrowing, AMT, and conjunctival flap procedures help stabilize the ocular surface and alleviate symptoms. Advanced methods like CN and SGT target the underlying pathology in refractory cases such as oGVHD. The outcomes vary depending on the disease severity and surgical approach. Each procedure carries specific risks and requires individualized patient selection. Therefore, a tailored approach based on clinical condition, anatomical involvement, and patient factors is essential to achieve optimal results. Ongoing innovations in reconstructive surgery and regenerative medicine are expected to further improve outcomes for patients with OSDs.<\/jats:p>","DOI":"10.3390\/life15071110","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T10:46:05Z","timestamp":1752662765000},"page":"1110","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oculoplastic Interventions in the Management of Ocular Surface Diseases: A Comprehensive Review"],"prefix":"10.3390","volume":"15","author":[{"given":"Seyed Mohsen","family":"Rafizadeh","sequence":"first","affiliation":[{"name":"Department of Oculofacial Plastic and Reconstructive Surgery, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1417614411, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Asadigandomani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of California San Francisco, San Francisco, CA 94143, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samin","family":"Khannejad","sequence":"additional","affiliation":[{"name":"Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6183-084X","authenticated-orcid":false,"given":"Arman","family":"Hasanzade","sequence":"additional","affiliation":[{"name":"Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Rezaei","sequence":"additional","affiliation":[{"name":"Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7436-0218","authenticated-orcid":false,"given":"Avery Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Bernice and Harvey Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6546-3546","authenticated-orcid":false,"given":"Mohammad","family":"Soleimani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"ref_1","first-page":"69","article-title":"Emergency management: Exposure keratopathy","volume":"31","author":"Mathenge","year":"2018","journal-title":"Community Eye Health"},{"key":"ref_2","first-page":"142","article-title":"Eye and Periocular Skin Involvement in Herpes Zoster Infection","volume":"4","author":"Kalogeropoulos","year":"2015","journal-title":"Med. Hypothesis Discov. Innov. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3341\/kjo.2018.0010","article-title":"Ophthalmologic Clinical Features of Facial Nerve Palsy Patients","volume":"33","author":"Lee","year":"2019","journal-title":"Korean J. Ophthalmol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Ka\u0161telan, S., Tomi\u0107, M., Salopek-Rabati\u0107, J., and Novak, B. (2013). Diagnostic procedures and management of dry eye. Biomed. Res. Int., 2013.","DOI":"10.1155\/2013\/309723"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/IIO.0000000000000185","article-title":"Innovations in Treatment of Lagophthalmos and Exposure Keratopathy","volume":"57","author":"Wolkow","year":"2017","journal-title":"Int. Ophthalmol. Clin."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000511223","article-title":"Adjunct Use of Therapeutic Scleral Lens for Exposure Keratopathy after Severe Chemical BurnAlternative therapies for dry eye disease","volume":"12","author":"Scanzera","year":"2021","journal-title":"Case Rep. Ophthalmol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12938-025-01396-3","article-title":"Facial expression deep learning algorithms in the detection of neurological disorders: A systematic review and meta-analysis","volume":"24","author":"Yoonesi","year":"2025","journal-title":"Biomed. Eng. Online"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1097\/ICO.0000000000003182","article-title":"Mustard gas\u2013induced ocular surface disorders: An update on the pathogenesis, clinical manifestations, and management","volume":"42","author":"Soleimani","year":"2023","journal-title":"Cornea"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ajo.2018.09.041","article-title":"Use of autologous serum tears for the treatment of ocular surface disease from patients with systemic autoimmune diseases","volume":"199","author":"Soleimani","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.drudis.2015.01.013","article-title":"Punctal plug: A medical device to treat dry eye syndrome and for sustained drug delivery to the eye","volume":"20","author":"Yellepeddi","year":"2015","journal-title":"Drug Discov. Today"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1016\/j.jfo.2018.12.003","article-title":"Punctal and canalicular plugs: Indications, efficacy and safety","volume":"42","author":"Best","year":"2019","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"9312340","DOI":"10.1155\/2016\/9312340","article-title":"Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease","volume":"2016","author":"Jehangir","year":"2016","journal-title":"J. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12348-025-00469-7","article-title":"Microbial contamination of therapeutic contact lenses after photorefractive keratectomy: A prospective analysis","volume":"15","author":"Soleimani","year":"2025","journal-title":"J. Ophthalmic Inflamm. Infect."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"505","DOI":"10.3349\/ymj.2022.0518","article-title":"Causes of Punctal plug loss in Sj\u00f6gren\u2019s syndrome","volume":"64","author":"Kim","year":"2023","journal-title":"Yonsei Med. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.ajo.2010.08.045","article-title":"Surgical punctal occlusion with a high heat-energy releasing cautery device for severe dry eye with recurrent punctal plug extrusion","volume":"151","author":"Ohba","year":"2011","journal-title":"Am. J. Ophthalmol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/ICO.0000000000002384","article-title":"Long-term Outcomes of Punctal Cauterization in the Management of Ocular Surface Diseases","volume":"40","author":"Wang","year":"2021","journal-title":"Cornea"},{"key":"ref_17","first-page":"1521","article-title":"Punctal occlusion for the dry eye. Three-year revision","volume":"104","author":"Kruoch","year":"1997","journal-title":"Am. Acad. Ophthalmol. Surg. Interv. Neurotrophic keratopathy. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1159\/000131091","article-title":"Surgical occlusion of the lacrimal drainage system","volume":"41","author":"Geerling","year":"2008","journal-title":"Dev Ophthalmol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/bmt.2012.50","article-title":"Surgical management of lacrimal punctal cauterization in chronic GVHD-related dry eye with recurrent punctal plug extrusion","volume":"47","author":"Yaguchi","year":"2012","journal-title":"Bone Marrow Transplant."},{"key":"ref_20","first-page":"10","article-title":"Performing a tarsorrhaphy","volume":"28","author":"Rajak","year":"2015","journal-title":"Community Eye Health"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.preteyeres.2018.04.003","article-title":"Neurotrophic keratopathy","volume":"66","author":"Dua","year":"2018","journal-title":"Prog Retin Eye Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/00003226-200111000-00002","article-title":"Tarsorrhaphy: Clinical experience from a cornea practice","volume":"20","author":"Cosar","year":"2001","journal-title":"Cornea"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s40265-021-01660-5","article-title":"Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets","volume":"82","author":"Dang","year":"2022","journal-title":"Drugs"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1097\/OPX.0000000000000659","article-title":"Ophthalmic Procedures for Treatment of Advanced Ocular Surface Diseases","volume":"92","author":"Bartlett","year":"2015","journal-title":"Optom. Vis. Sci."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/01676830.2016.1193543","article-title":"Tarsal suture tarsorrhaphy: Quick, safe and effective corneal protection","volume":"35","author":"Thaller","year":"2016","journal-title":"Orbit"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/s12016-014-8438-7","article-title":"Current Approach to Dry Eye Disease","volume":"49","author":"Valim","year":"2015","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"ref_27","first-page":"282","article-title":"Use of Botulinum Neurotoxin in OphthalmologyA randomized clinical trial to evaluate the usefulness of amniotic membrane transplantation in bacterial keratitis healing","volume":"46","author":"Tabatabaei","year":"2016","journal-title":"Turk. J. Ophthalmol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Ho, R.W., Fang, P.C., Chang, C.H., Liu, Y.P., and Kuo, M.T. (2019). A Review of Periocular Botulinum Neurotoxin on the Tear Film Homeostasis and the Ocular Surface Change. Toxins, 11.","DOI":"10.3390\/toxins11020066"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0002-9394(99)00408-0","article-title":"Effect of eyelid botulinum toxin injection on lacrimal drainage","volume":"129","author":"Sahlin","year":"2000","journal-title":"Am. J. Ophthalmol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000131089","article-title":"Eyelid botulinum toxin injections for the dry eye","volume":"41","author":"Sahlin","year":"2008","journal-title":"Dev Ophthalmol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/ICU.0000000000000506","article-title":"Botulinum toxin injection and tear production","volume":"29","author":"Alsuhaibani","year":"2018","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_32","first-page":"53","article-title":"Acute calcareous corneal degeneration in a patient with chronic graft-versus-host disease","volume":"68","author":"Ruiz","year":"2024","journal-title":"Rom. J. Ophthalmol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.sjopt.2014.09.009","article-title":"Neuro-ophthalmological approach to facial nerve palsy","volume":"29","author":"Portelinha","year":"2015","journal-title":"Saudi J. Ophthalmol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00129492-200105000-00022","article-title":"Long-term outcome of gold eyelid weights in patients with facial nerve palsy","volume":"22","author":"Harrisberg","year":"2001","journal-title":"Otol. Neurotol."},{"key":"ref_35","first-page":"891","article-title":"Low-level versus high-level placement of gold plates in the upper eyelid in patients with facial palsy","volume":"5","author":"Amer","year":"2011","journal-title":"Clin Ophthalmol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"110234","DOI":"10.1016\/j.exer.2025.110234","article-title":"A deep dive into radiation keratopathy; going beyond the current frontierss","volume":"251","author":"Soleimani","year":"2025","journal-title":"Exp. Eye Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/ICU.0000000000000510","article-title":"Controversies in periocular reconstruction for facial nerve palsy","volume":"29","author":"Allen","year":"2018","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13561-024-00506-6","article-title":"Factors influencing medical expenditures in patients with unresolved facial palsy and pharmacoeconomic analysis of upper eyelid lid loading with gold and platinum weights compared to tarsorrhaphyM\u00fcller\u2019s muscle excision and levator recession in retracted upper lid. Treatment of thyroid-related retraction","volume":"14","author":"Gospodarowicz","year":"2024","journal-title":"Health Econ. Rev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s00266-011-9740-x","article-title":"Lid loading for treatment of paralytic lagophthalmos","volume":"35","author":"Yu","year":"2011","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1080\/09273948.2017.1311922","article-title":"Type IV Hypersensitivity to Gold Weight Upper-Eyelid Implant: Case Report and Review of the Literature","volume":"26","author":"Kilduff","year":"2018","journal-title":"Ocul. Immunol. Inflamm."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1001\/archophthalmol.2011.255","article-title":"Histological evidence of tissue reaction to platinum eyelid chain","volume":"129","author":"Chan","year":"2011","journal-title":"Arch. Ophthalmol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1177\/00034894221148016","article-title":"Symptomatic and Histological Tissue Reaction to Upper Eyelid Platinum Weight","volume":"132","author":"Ghodke","year":"2023","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.fsc.2015.09.003","article-title":"Management of the Eye in Facial Paralysis","volume":"24","author":"Chi","year":"2016","journal-title":"Facial Plast. Surg. Clin. N. Am."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Asadigandomani, H., Rajabi, M.T., Aghajani, A., Mousavi, S.A., Rahmanikhah, E., Abedinifar, Z., Afshar, P., and Rafizadeth, S.M. (2024). The continuous rise in orbital subperiosteal abscess incidence in the Iranian pediatric population. Sci. Rep., 14.","DOI":"10.1038\/s41598-024-74447-9"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Irawati, Y., Natalia, M.E.R., Gondhowiardjo, T.D., Dachlan, I., and Soebono, H. (2022). Modified tarsorrhaphy versus gold weight implant technique for paralytic lagophthalmos treatment in patients with leprosy: One-year observation of a randomized controlled trial study. Front. Med., 9.","DOI":"10.3389\/fmed.2022.941082"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1136\/bjophthalmol-2017-310525","article-title":"Non-aesthetic indications for periocular hyaluronic acid filler treatment: A review","volume":"102","author":"Tan","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"ref_47","first-page":"85","article-title":"Non-surgical treatment for eyelid retraction in thyroid eye disease (TED) Innovations in Treatment of Lagophthalmos and Exposure Keratopathy","volume":"57","author":"Grisolia","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_48","first-page":"E91","article-title":"Hyaluronic acid gel weight: A nonsurgical option for the management of paralytic lagophthalmos","volume":"123","author":"Lowy","year":"2013","journal-title":"Laryngoscope"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/IOP.0b013e318192568d","article-title":"Use of hyaluronic Acid gel in the management of paralytic lagophthalmos: The hyaluronic Acid gel \u201cgold weight\u201d","volume":"25","author":"Mancini","year":"2009","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"603","DOI":"10.18240\/ijo.2024.03.25","article-title":"Late infection after peri-orbital autologous micro-fat graft: A case presentation and literature review","volume":"17","author":"Pakdel","year":"2024","journal-title":"Int. J. Ophthalmol."},{"key":"ref_51","unstructured":"Cochran, M.L., Lopez, M.J., and Czyz, C.N. (2025). Anatomy, Head and Neck: Eyelid. StatPearls, StatPearls Publishing LLC."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0161-6420(81)34987-2","article-title":"Surgical treatment of thyroid-related upper eyelid retraction. Graded M\u00fcller\u2019s muscle excision and levator recession","volume":"88","author":"Putterman","year":"1981","journal-title":"Ophthalmology"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Asadigandomani, H., Rajabi, M.T., Mohsenzadeh Kermani, N., Nozarian, Z., Ghaedamini, M., and Rafizadeh, S.M. (2025). Muller\u2019s muscle fibrosis is a possible predictive factor in the outcome of Muller\u2019s muscle-conjunctival resection. BMC Ophthalmol., 25.","DOI":"10.1186\/s12886-025-04115-7"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1001\/archopht.123.9.1221","article-title":"M\u00fcllerectomy for upper eyelid retraction and lagophthalmos due to facial nerve palsy","volume":"123","author":"Hassan","year":"2005","journal-title":"Arch. Ophthalmol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/aos.12404","article-title":"Levator recession with adjustable sutures for correction of upper eyelid retraction in thyroid eye disease","volume":"92","author":"Ueland","year":"2014","journal-title":"Acta Ophthalmol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1007\/s00266-022-02770-5","article-title":"Upper Eyelid Retraction in Graves\u2019 Ophthalmopathy: Our Surgical Experience on 153 Cases of Full-Thickness Anterior Blepharotomy with Mullerectomy","volume":"46","author":"Guastella","year":"2022","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_57","first-page":"94","article-title":"Transconjunctival M\u00fcller muscle recession with levator disinsertion for correction of eyelid retraction associated with thyroid-related orbitopathy","volume":"140","author":"Mansury","year":"2005","journal-title":"Am. J. Ophthalmol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1001\/archopht.1934.00830100011001","article-title":"Recession of the levator muscle for lagophthalmos in exophthalmic goiter","volume":"11","author":"Goldstein","year":"1934","journal-title":"Arch. Ophthalmol."},{"key":"ref_59","first-page":"70","article-title":"A surgical procedure for retraction of eyelids in endocrine exophthalmos (a moving picture)","volume":"63","author":"Henderson","year":"1965","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1097\/ICU.0b013e3283499433","article-title":"A review of surgical techniques to correct upper eyelid retraction associated with thyroid eye disease","volume":"22","author":"Kazim","year":"2011","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1001\/archopht.1972.01000020403007","article-title":"Surgical treatment of upper eyelid retraction","volume":"87","author":"Putterman","year":"1972","journal-title":"Arch. Ophthalmol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1001\/archopht.1979.01020020149013","article-title":"M\u00fcller\u2019s muscle excision and levator recession in retracted upper lid. Treatment of thyroid-related retraction","volume":"97","author":"Chalfin","year":"1979","journal-title":"Arch. Ophthalmol."},{"key":"ref_63","first-page":"67","article-title":"Graded full-thickness anterior blepharotomy for upper eyelid retraction","volume":"101","author":"Elner","year":"2003","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4103\/tjo.tjo_57_21","article-title":"Management of eyelid retraction related to thyroid eye diseaseCorneal Neurotization: A Meta-analysis of Outcomes and Patient Selection Factors","volume":"12","author":"Osaki","year":"2022","journal-title":"Taiwan J. Ophthalmol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1136\/bjo.2004.052852","article-title":"Full thickness eyelid transsection (blepharotomy) for upper eyelid lengthening in lid retraction associated with Graves\u2019 disease","volume":"89","author":"Hintschich","year":"2005","journal-title":"Br. J. Ophthalmol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/eye.2013.160","article-title":"Turn-over orbital septal flap and levator recession for upper-eyelid retraction secondary to thyroid eye disease","volume":"27","author":"Watanabe","year":"2013","journal-title":"Eye"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/1120672119881984","article-title":"Levator recession and minimal lateral tarsorrhaphy for the management of lagophthalmos and corneal exposure in facial palsy","volume":"31","author":"Eshraghi","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/IOP.0000000000000116","article-title":"Graded m\u00fcllerectomy for correction of graves upper eyelid retraction: Effect on eyelid movements","volume":"30","author":"Ribeiro","year":"2014","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.1097\/IOP.0000000000002543","article-title":"Eyelid Surgery in Thyroid Eye Disease","volume":"39","author":"Naik","year":"2023","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/asj\/sjx003","article-title":"Comparison of Efficacy and Complications Among Various Spacer Grafts in the Treatment of Lower Eyelid Retraction: A Systematic Review","volume":"37","author":"Park","year":"2017","journal-title":"Aesthetic Surg. J."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1080\/08820538.2023.2273850","article-title":"Surgical Correction of Cicatricial Lower Eyelid Retraction: A Systematic Review","volume":"39","author":"Rafizadeh","year":"2024","journal-title":"Semin. Ophthalmol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/PRS.0b013e3181904d3a","article-title":"Corneal neurotization: A novel solution to neurotrophic keratopathy","volume":"123","author":"Terzis","year":"2009","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Feinberg, K., Tajdaran, K., Mirmoeini, K., Daeschler, S.C., Henriquez, M.A., Stevens, K.E., Mulenga, C.M., Hussain, A., Hamrah, P., and Ali, A. (2023). The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms241612615"},{"key":"ref_74","first-page":"2623","article-title":"Efficacy of treatments for neurotrophic keratopathy: A systematic review and meta-analysis","volume":"260","author":"Roumeau","year":"2022","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"ref_75","first-page":"CD015723","article-title":"Medical and surgical interventions for neurotrophic keratopathy","volume":"2023","author":"Kruoch","year":"2023","journal-title":"Cochrane Database Syst Rev."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3109\/08820538.2013.768678","article-title":"A comparison of the efficacy of autologous serum eye drops with amniotic membrane transplantation in neurotrophic keratitis","volume":"29","author":"Turkoglu","year":"2014","journal-title":"Semin. Ophthalmol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12348-024-00417-x","article-title":"Clinical characteristics, predisposing factors, and management of moraxella keratitis in a tertiary eye hospital","volume":"14","author":"Soleimani","year":"2024","journal-title":"J. Ophthalmic Inflamm. Infect."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s10792-024-03106-9","article-title":"Unveiling the landscape of post-keratoplasty keratitis: A comprehensive epidemiological analysis in a tertiary center","volume":"44","author":"Soleimani","year":"2024","journal-title":"Int. Ophthalmol."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Jahani, S., Rezaeimanesh, N., Owji, M., Arab Bafrani, M., Mohammadi Lapevandani, M., and Naser Moghadasi, A. (2025). Current treatment and management of neuromyelitis optica spectrum disorder: Areas for improvement. Expert. Rev. Ophthalmol., 1\u201311.","DOI":"10.1080\/17469899.2025.2489737"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"111146","DOI":"10.1016\/j.jocn.2025.111146","article-title":"Environmental risk factors of late-onset multiple sclerosis: A population-based case-control study","volume":"135","author":"Kasbi","year":"2025","journal-title":"J. Clin. Neurosci."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"e70439","DOI":"10.1002\/brb3.70439","article-title":"Uncovering the Causal Link Between Obesity-Associated Genes and Multiple Sclerosis: A Systematic Literature Review","volume":"15","author":"Jafari","year":"2025","journal-title":"Brain Behav."},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Bafrani, M.A., Rios, V., Kim, M.J., Balan, A., and Bove, R. (2025). Gynecological health: A missing link in comprehensive treatment monitoring for multiple sclerosis. Mult. Scler., 13524585251346371.","DOI":"10.1177\/13524585251346371"},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Dragnea, D.C., Krolo, I., Koppen, C., Faris, C., Van den Bogerd, B., N\u00ed Dhubhghaill, S., Bulut, O., Palamar, M., Yaman, B., and Egrilmez, S. (2023). Corneal Neurotization-Indications, Surgical Techniques and OutcomesAmniotic Membrane Transplantation for Reconstruction of Ocular Surface Lesion Excisions in Pediatric Population. J. Clin. Med., 12.","DOI":"10.3390\/jcm12062214"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1080\/07853890.2022.2045035","article-title":"Neurotrophic keratopathy: Current challenges and future prospects","volume":"54","author":"NaPier","year":"2022","journal-title":"Ann. Med."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/APO.0000000000000626","article-title":"Evaluation of Corneal Nerve Regeneration After Minimally Invasive Corneal Neurotization","volume":"12","author":"Su","year":"2023","journal-title":"Asia Pac. J. Ophthalmol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1001\/jamaophthalmol.2014.2316","article-title":"Restoration of corneal sensation with regional nerve transfers and nerve grafts: A new approach to a difficult problem","volume":"132","author":"Elbaz","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"e5334","DOI":"10.1097\/GOX.0000000000005334","article-title":"Corneal Neurotization: Preoperative Patient Workup and Surgical Decision-makingSurgical Correction of Cicatricial Lower Eyelid Retraction: A Systematic Review","volume":"11","author":"Daeschler","year":"2023","journal-title":"Plast. Reconstr. Surg. Glob. Open"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/IOP.0000000000000913","article-title":"Endoscopic Corneal Neurotization: Cadaver Feasibility Study","volume":"34","author":"Leyngold","year":"2018","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/SAP.0000000000003117","article-title":"Corneal Neurotization: A Meta-analysis of Outcomes and Patient Selection Factors","volume":"88","author":"Swanson","year":"2022","journal-title":"Ann. Plast. Surg."},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Saini, M., Kalia, A., Jain, A.K., Gaba, S., Malhotra, C., Gupta, A., Soni, T., Saini, K., Gupta, P.C., and Singh, M. (2023). Clinical outcomes of corneal neurotization using sural nerve graft in neurotrophic keratopathy. PLoS ONE, 18.","DOI":"10.1371\/journal.pone.0294756"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/bjophthalmol-2020-317361","article-title":"Outcomes of corneal neurotisation using processed nerve allografts: A multicentre case series","volume":"106","author":"Sweeney","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/IOP.0000000000001181","article-title":"Minimally invasive corneal neurotization with acellular nerve allograft: Surgical technique and clinical outcomes","volume":"35","author":"Leyngold","year":"2019","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_93","first-page":"1724","article-title":"Treatment of neurotrophic keratopathy with minimally invasive corneal neurotisation: Long-term clinical outcomes and evidence of corneal reinnervation","volume":"103","author":"Catapano","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ajo.2022.04.013","article-title":"Minimally invasive corneal neurotization provides sensory function, protects against recurrent ulceration, and improves visual acuity","volume":"241","author":"Woo","year":"2022","journal-title":"Am. J. Ophthalmol."},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Elalfy, M., Maqsood, S., Hau, S., Kannan, R.Y., Nduka, C., Hamada, S., and Malhotra, R. (2021). Functional and structural changes following corneal neurotisation in the management of neurotrophic keratopathy: UK single centre series. Clin. Ophthalmol., 2149\u20132160.","DOI":"10.2147\/OPTH.S298941"},{"key":"ref_96","first-page":"243","article-title":"Amniotic membrane transplantation in the human eye","volume":"108","author":"Meller","year":"2011","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_97","doi-asserted-by":"crossref","unstructured":"Ganger, A., Vanathi, M., Mohanty, S., and Tandon, R. (2015). Long-Term Outcomes of Cultivated Limbal Epithelial Transplantation: Evaluation and Comparison of Results in Children and Adults. Biomed. Res. Int., 2015.","DOI":"10.1155\/2015\/480983"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/S0181-5512(06)73902-X","article-title":"Advantages of amniotic membrane transplantation in eye surface diseases","volume":"29","author":"Muraine","year":"2006","journal-title":"J. Francais D Ophtalmol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4103\/0301-4738.33036","article-title":"Amniotic membrane transplantation: A review of current indications in the management of ophthalmic disorders","volume":"55","author":"Sangwan","year":"2007","journal-title":"Indian. J. Ophthalmol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1007\/s10792-022-02493-1","article-title":"Impact of adjuvant amniotic membrane transplantation in infectious ulcerative keratitis","volume":"43","author":"Bulut","year":"2023","journal-title":"Int. Ophthalmol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/0974-620X.83656","article-title":"Amniotic membrane transplantation: An option for ocular surface disorders","volume":"4","author":"Thatte","year":"2011","journal-title":"Oman J. Ophthalmol."},{"key":"ref_102","first-page":"177","article-title":"New clinical application of amniotic membrane transplant for ocular surface disease","volume":"9","author":"Gheorghe","year":"2016","journal-title":"J. Med. Life"},{"key":"ref_103","first-page":"798","article-title":"Amniotic membrane graft in ocular surface disease. Prospective study with 31 cases","volume":"24","author":"Muraine","year":"2001","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jtos.2017.01.004","article-title":"A randomized clinical trial to evaluate the usefulness of amniotic membrane transplantation in bacterial keratitis healing","volume":"15","author":"Tabatabaei","year":"2017","journal-title":"Ocul. Surf."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1136\/bjo.85.12.1455","article-title":"Single and multilayer amniotic membrane transplantation for persistent corneal epithelial defect with and without stromal thinning and perforation","volume":"85","author":"Prabhasawat","year":"2001","journal-title":"Br. J. Ophthalmol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.ophtha.2004.11.041","article-title":"Intraoperative mitomycin C and amniotic membrane transplantation for fornix reconstruction in severe cicatricial ocular surface diseases","volume":"112","author":"Tseng","year":"2005","journal-title":"Ophthalmology"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1186\/s12886-021-01925-3","article-title":"Two case reports of continued progression of chronic ocular graft-versus-host disease without concurrent systemic comorbidities treated by amniotic membrane transplantation","volume":"21","author":"Ikarashi","year":"2021","journal-title":"BMC Ophthalmol."},{"key":"ref_108","first-page":"e16678","article-title":"Glueless and sutureless multi-layer amniotic membrane transplantation in a patient with pending corneal perforation","volume":"13","author":"Lavaris","year":"2021","journal-title":"Cureus"},{"key":"ref_109","first-page":"3412","article-title":"Conjunctival flap surgery in the management of ocular surface disease (Review)","volume":"20","author":"Zemba","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/ICO.0b013e3181963cbe","article-title":"Gundersen flaps in the management of ocular surface disease in an Asian population","volume":"28","author":"Lim","year":"2009","journal-title":"Cornea"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S1542-0124(12)70050-2","article-title":"Science and strategy for preventing and managing corneal ulceration","volume":"5","author":"Tuli","year":"2007","journal-title":"Ocul. Surf."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/sj.eye.6701814","article-title":"Superior forniceal conjunctival advancement pedicles (SFCAP) in the management of acute and impending corneal perforations","volume":"20","author":"Sandinha","year":"2006","journal-title":"Eye"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1001\/archopht.121.8.1189","article-title":"Microsurgical approach to the conjunctival flap","volume":"121","author":"Khodadoust","year":"2003","journal-title":"Arch. Ophthalmol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ajo.2021.02.022","article-title":"Incidence, risk factors and complications of ocular graft-versus-host disease following hematopoietic stem cell transplantation","volume":"227","author":"Pellegrini","year":"2021","journal-title":"Am. J. Ophthalmol."},{"key":"ref_115","doi-asserted-by":"crossref","unstructured":"Xu, Y., Wang, Y.-M., Sun, Z.-T., Yang, X.-L., Zhuang, X.-Y., Ren, Y.-R., Chen, Y.-J., Chen, F., Ma, X., and Tang, X.-W. (2022). Corneal perforation associated with ocular graft-versus-host disease. Front. Oncol., 12.","DOI":"10.3389\/fonc.2022.962250"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.ajo.2022.05.019","article-title":"Submandibular Gland Transplantation vs Minor Salivary Glands Transplantation for Treatment of Dry Eye: A Retrospective Cohort Study","volume":"241","author":"Su","year":"2022","journal-title":"Am. J. Ophthalmol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000131093","article-title":"Minor salivary gland transplantation","volume":"41","author":"Geerling","year":"2008","journal-title":"Dev. Ophthalmol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jtos.2019.04.007","article-title":"Quality of life and patient satisfaction after submandibular gland transplantation in patients with severe dry eye disease","volume":"17","author":"Su","year":"2019","journal-title":"Ocul. Surf."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Chen, J., Bai, T., Su, J., Cong, X., Lv, L., Tong, L., Yu, H., Feng, Y., and Yu, G. (2024). Salivary Gland Transplantation as a Promising Approach for Tear Film Restoration in Severe Dry Eye Disease. J. Clin. Med., 13.","DOI":"10.3390\/jcm13020521"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1136\/bjophthalmol-2020-316611","article-title":"Minor salivary gland transplantation for severe dry eye disease due to cicatrising conjunctivitis: Multicentre long-term outcomes of a modified technique","volume":"105","author":"Vazirani","year":"2021","journal-title":"Br. J. Ophthalmol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/art.39859","article-title":"2016 American College of Rheumatology\/European League Against Rheumatism Classification Criteria for Primary Sj\u00f6gren\u2019s Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts","volume":"69","author":"Shiboski","year":"2017","journal-title":"Arthritis Rheumatol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ijom.2018.07.006","article-title":"Factors influencing the long-term results of autologous microvascular submandibular gland transplantation for severe dry eye disease","volume":"48","author":"Zhang","year":"2019","journal-title":"Int. J. Oral. Maxillofac. Surg."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1097\/ICO.0000000000001358","article-title":"Minor Salivary Gland Transplantation for Severe Dry Eyes","volume":"36","author":"Wakamatsu","year":"2017","journal-title":"Cornea"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"601","DOI":"10.2217\/rme-2016-0054","article-title":"Advances in corneal cell therapy","volume":"11","author":"Fuest","year":"2016","journal-title":"Regen Med."},{"key":"ref_125","first-page":"321","article-title":"Long-term results of autologous transplantation of limbal epithelium cultivated ex vivo for limbal stem cell deficiency","volume":"113","author":"Scholz","year":"2016","journal-title":"Der. Ophthalmol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1002\/sctm.19-0021","article-title":"Long-term results of cultured limbal stem cell versus limbal tissue transplantation in stage III limbal deficiency","volume":"8","author":"Borderie","year":"2019","journal-title":"Stem Cells Transl. Med."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.2147\/OPTH.S181035","article-title":"Amniotic membrane transplantation with or without autologous cultivated limbal stem cell transplantation for the management of partial limbal stem cell deficiency","volume":"12","author":"Sharma","year":"2018","journal-title":"Clin. Ophthalmol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s13287-015-0009-1","article-title":"Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: A prospective case series","volume":"6","author":"Bobba","year":"2015","journal-title":"Stem Cell Res. Ther."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"e016487","DOI":"10.1136\/bmjopen-2017-016487","article-title":"A study protocol for a multicentre randomised clinical trial evaluating the safety and feasibility of a bioengineered human allogeneic nanostructured anterior cornea in patients with advanced corneal trophic ulcers refractory to conventional treatment","volume":"7","author":"Mata","year":"2017","journal-title":"BMJ Open"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s10561-016-9575-4","article-title":"Long-term result of autologous cultivated oral mucosal epithelial transplantation for severe ocular surface disease","volume":"17","author":"Prabhasawat","year":"2016","journal-title":"Cell Tissue Bank"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"5192","DOI":"10.1167\/iovs.15-17953","article-title":"Regeneration of corneal epithelium with dental pulp stem cells using a contact lens delivery system","volume":"57","author":"Kushnerev","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.stemcr.2013.12.014","article-title":"Small-molecule induction promotes corneal epithelial cell differentiation from human induced pluripotent stem cells","volume":"2","author":"Mikhailova","year":"2014","journal-title":"Stem Cell Rep."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jtos.2025.05.009","article-title":"Safety of Subconjunctival Injection of Mesenchymal Stromal Cells in Persistent Corneal Epithelial Disease\u2013A Phase 1b Clinical Trial","volume":"38","author":"Tu","year":"2025","journal-title":"Ocul. Surf."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jtos.2020.11.013","article-title":"Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease","volume":"19","author":"Larsen","year":"2021","journal-title":"Ocul. Surf."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1038\/bmt.2010.195","article-title":"Mesenchymal stem cell as salvage treatment for refractory chronic GVHD","volume":"45","author":"Weng","year":"2010","journal-title":"Bone Marrow Transpl."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1038\/mt.2012.208","article-title":"Mesenchymal stromal cells treatment attenuates dry eye in patients with chronic graft-versus-host disease","volume":"20","author":"Weng","year":"2012","journal-title":"Mol. Ther."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jtos.2023.09.008","article-title":"Intrastromal versus subconjunctival injection of mesenchymal stem\/stromal cells for promoting corneal repair","volume":"30","author":"Soleimani","year":"2023","journal-title":"Ocul. Surf."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1080\/14712598.2023.2175605","article-title":"Applications of mesenchymal stem cells in ocular surface diseases: Sources and routes of delivery","volume":"23","author":"Soleimani","year":"2023","journal-title":"Expert Opin. Biol. Ther."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"eabj9617","DOI":"10.1126\/sciadv.abj9617","article-title":"miR-204\u2013containing exosomes ameliorate GVHD-associated dry eye disease","volume":"8","author":"Zhou","year":"2022","journal-title":"Sci. Adv."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/7\/1110\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:10:29Z","timestamp":1760033429000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/15\/7\/1110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,16]]},"references-count":139,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["life15071110"],"URL":"https:\/\/doi.org\/10.3390\/life15071110","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,16]]}}}