{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:31:36Z","timestamp":1760059896616,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Background: Arachnoid cysts are typically benign and asymptomatic, but large cysts can exert a mass effect on adjacent neural structures. Based on the available literature, no cases of cortical visual impairment (CVI) in an adolescent caused by posterior fossa arachnoid cysts have been reported. Case presentation: We report the case of a previously healthy 16-year-old girl who presented with sudden and rapidly progressive bilateral visual loss due to a large retrocerebellar arachnoid cyst. She reported blurred vision, tunnel vision-like, and decreased visual acuity. Although neuro-ophthalmologic and imaging workup revealed no damage to the anterior visual pathways, she exhibited progressive visual decline. Functional tests confirmed bilateral cortical visual impairment: pattern-reversal visual evoked potentials (VEPs) showed preserved and symmetric P100 latencies and amplitudes, while automated perimetry revealed bilateral concentric visual field constriction with preserved central islands. Following cystoperitoneal drainage, her vision rapidly and completely recovered. Conclusions: To the best of our knowledge, this is the first reported case of reversible CVI in an adolescent caused by a posterior fossa arachnoid cyst without intracranial pressure (ICP) elevation or optic nerve involvement, and with tunnel vision-like. Our findings emphasize the role of posterior fossa lesions in visual dysfunction and highlight the potential reversibility of cortical visual loss when timely decompression is achieved. This case underscores the importance of including posterior fossa lesions in the differential diagnosis of unexplained bilateral visual loss, even in the absence of elevated intracranial pressure or anterior visual pathway involvement.<\/jats:p>","DOI":"10.3390\/life15071121","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T10:33:47Z","timestamp":1752748427000},"page":"1121","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reversible Cortical Visual Impairment in an Adolescent Due to a Posterior Fossa Arachnoid Cyst: A Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"Jelena","family":"\u0160kunca Herman","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario Josip","family":"\u017divkovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Ore\u0161kovi\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lana","family":"Kne\u017eevi\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Malenica Ravli\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanka","family":"Doko Mandi\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goran","family":"Mari\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ante","family":"Vukojevi\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hrvoje","family":"Sliep\u010devi\u0107","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, General County Hospital Vinkovci, 32100 Vinkovci, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mia","family":"Zori\u0107 Geber","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Kalousek","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran","family":"Vatavuk","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sestre Milosrdnice University Hospital Centre, 10000 Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3340\/jkns.2016.59.3.314","article-title":"Rapid Visual Deterioration Caused by Posterior Fossa Arachnoid Cyst","volume":"59","author":"Shin","year":"2016","journal-title":"J. Korean Neurosurg. Soc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3171\/2012.10.JNS12548","article-title":"Prevalence and natural history of arachnoid cysts in adults","volume":"118","author":"Terman","year":"2013","journal-title":"J. Neurosurg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3171\/2010.2.PEDS09464","article-title":"Prevalence and natural history of arachnoid cysts in children","volume":"5","author":"Yew","year":"2010","journal-title":"J. Neurosurg. Pediatr."},{"key":"ref_4","first-page":"e83894","article-title":"A comprehensive review of arachnoid cysts","volume":"17","author":"Wang","year":"2025","journal-title":"Cureus"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.pediatrneurol.2024.04.008","article-title":"Optic nerve edema in pediatric middle cranial fossa arachnoid cysts: Report of 51 patients from a single institution","volume":"156","author":"Papadakis","year":"2024","journal-title":"Pediatr. Neurol."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Gotz Wieckowska, A., G\u0142\u00f3wka, \u0141., Br\u0105zert, A., and Pawlak, M. (2017). Ophthalmological symptoms in children with intracranial cysts. Sci. Rep., 7.","DOI":"10.1038\/s41598-017-13266-7"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.3171\/foc.2007.22.2.7","article-title":"Arachnoid cysts: Case series and review of the literature","volume":"22","author":"Pradilla","year":"2007","journal-title":"Neurosurg. Focus."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1097\/00007611-200111000-00016","article-title":"Rapidly progressive visual loss caused by a sellar arachnoid cyst: Reversal with transsphenoidal microsurgery","volume":"94","author":"Weil","year":"2001","journal-title":"S. Med. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"134","DOI":"10.2176\/nmc.49.134","article-title":"Delayed recurrent arachnoid cyst of the occipital convexity in an elderly woman","volume":"49","author":"Suzuki","year":"2009","journal-title":"Neurol. Med. Chir."},{"key":"ref_10","first-page":"1125","article-title":"A case of symptomatic arachnoid cyst of the occipital convexity in an adult","volume":"34","author":"Yagi","year":"2006","journal-title":"No Shinkei Geka"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00247-004-1253-1","article-title":"A different approach to cysts of the posterior fossa","volume":"34","author":"Nelson","year":"2004","journal-title":"Pediatr. Radiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1007\/BF00776713","article-title":"Posterior fossa cysts: Clinical, neuroradiological and surgical features","volume":"7","author":"Arai","year":"1991","journal-title":"Childs Nerv. Syst."},{"key":"ref_13","unstructured":"Sarkar, S., and Tripathy, K. (2025, July 12). Cortical Blindness, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK560626\/."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1053\/siny.2001.0078","article-title":"Cerebral visual impairment in children","volume":"6","author":"Dutton","year":"2001","journal-title":"Semin. Neonatol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1167\/iovs.62.6.15","article-title":"Cerebral Visual Impairment Characterized by Abnormal Visual Orienting Behavior with Preserved Visual Cortical Activation","volume":"62","author":"Kelly","year":"2021","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0039-6257(94)90073-6","article-title":"Cortical visual impairment in children","volume":"38","author":"Good","year":"1994","journal-title":"Surv. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijscr.2016.03.033","article-title":"Intrasellar arachnoid cyst: A case report and review of the literature","volume":"23","author":"HamitAytar","year":"2016","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_18","first-page":"827","article-title":"Visual loss related to papilledema: Report of 5 cases","volume":"23","author":"Suh","year":"1994","journal-title":"J. Korean Neurosurg. Soc."},{"key":"ref_19","first-page":"e2458","article-title":"Management of Arachnoid Cysts: A Comprehensive Review","volume":"10","author":"Mustansir","year":"2018","journal-title":"Cureus"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1212\/WNL.52.1.156","article-title":"Visual symptoms with dural arteriovenous malformations draining into occipital veins","volume":"52","author":"Kupersmith","year":"1999","journal-title":"Neurology"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"e847","DOI":"10.1016\/j.wneu.2021.09.029","article-title":"Avoidance and Improvement in Visual Field Defect After Surgery for Metastatic Brain Tumors in the Parietal and the Occipital Lobe","volume":"155","author":"Tanaka","year":"2021","journal-title":"World Neurosurg."},{"key":"ref_22","unstructured":"Ruddy, J.M., and Cardenas, A.C. (2025, July 12). Hemianopsia, StatPearls, Available online: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK562262\/."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Maia da Silva, M.N., Millington, R.S., Bridge, H., James-Galton, M., and Plant, G.T. (2017). Visual Dysfunction in Posterior Cortical Atrophy. Front. Neurol., 8.","DOI":"10.3389\/fneur.2017.00389"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1866-1955-5-21","article-title":"Intracranial arachnoid cysts: Impairment of higher cognitive functions and postoperative improvement","volume":"5","author":"Gjerde","year":"2013","journal-title":"J. Neurodev. Disord."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e163","DOI":"10.1016\/j.wneu.2024.09.061","article-title":"Symptomatic and Radiographic Improvement Following Surgery for Posterior Fossa Arachnoid Cysts: Meta-Analysis and Literature Review","volume":"192","author":"Lockard","year":"2024","journal-title":"World Neurosurg."},{"key":"ref_26","first-page":"97","article-title":"Acute onset of visual disturbance in a patient with arachnoid cyst in the middle cranial fossa","volume":"60","author":"Ishii","year":"2008","journal-title":"Brain Nerve"},{"key":"ref_27","unstructured":"Stubgen, J.P. (2025, May 27). Reversible, Chronic Homonymous Hemianopia due to a Suprasellar Arachnoid Cyst in An Elderly Patient. Consultant360. 10 June 2014. Available online: https:\/\/www.consultant360.com\/articles\/reversible-chronic-homonymous-hemianopia-due-suprasellar-arachnoid-cyst-elderly-patient."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.pediatrneurol.2014.09.005","article-title":"A boy with arachnoid cyst, a fall, and temporary and reversible visual impairment","volume":"51","author":"Menon","year":"2014","journal-title":"Pediatr. Neurol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jaapos.2023.01.011","article-title":"Ophthalmic manifestations of ruptured arachnoid cysts in children","volume":"27","author":"Mayeda","year":"2023","journal-title":"J. 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