{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T07:15:41Z","timestamp":1766387741923,"version":"3.48.0"},"reference-count":40,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Provost\u2019s Undergraduate Research Fund Award, Brandeis University"},{"name":"Harry N. Lee Family Chair in Innovation at the Lahey Hospital & Medical Center, Beth Israel Lahey Health, Beth Israel Lahey Health"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Glaucoma is one of the most common causes of irreversible visual impairment world wide. Providing low vision rehabilitation (LVR) services is a primary mode of support for patients with permanent vision loss. This retrospective, cross-sectional study evaluated the rate at which patients with severe open-angle glaucoma (OAG) were referred for LVR services at an academic medical center. Patient demographics, glaucoma severity, appointment history, performance on visual field (VF) testing, presenting visual acuity (VA), and change in best-corrected visual acuity (BCVA) after low vision refraction were abstracted from the electronic record and summarized by using descriptive statistics. Logistic regression analysis was used to assess the relationship between study variables and the likelihood of referral for LVR evaluation. Out of 522 patients with severe OAG, 88% of whom qualified as having low vision, 14 were referred for an LVR evaluation (2.7%). Referrals were most strongly associated with VA (adjusted odds ratio [aOR], 7.20; 95% confidence interval [CI], 2.11\u201324.64, p = 0.001) but not glaucoma-associated VF loss (aOR, 0.90; 95% CI, 0.24\u20133.37, p = 0.876). Thirteen of 14 patients referred for LVR completed visits (93%). More than one-third of those patients improved in their better-seeing eye after a low vision refraction, gaining an average of \u22120.18 \u00b1 0.24 logMAR (half gaining \u22652-lines of BCVA). Patients with severe OAG are at risk of progressive visual disability from their eye disease. We found, however, that the majority of these patients were not referred to LVR services, despite meeting eligibility criteria and growing evidence demonstrating their potential benefit.<\/jats:p>","DOI":"10.3390\/life16010012","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T07:01:33Z","timestamp":1766386893000},"page":"12","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated with Referral to Low Vision for Patients with Advanced Glaucoma"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3254-7364","authenticated-orcid":false,"given":"Julia","family":"Ernst","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Tufts University School of Medicine\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"},{"name":"Division of Ophthalmology, Department of Surgery, UMass Chan\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology, Department of Surgery, UMass Chan\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"},{"name":"Brandeis University, Waltham, MA 02453, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakob","family":"Tsosie","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tufts University School of Medicine\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5504-812X","authenticated-orcid":false,"given":"David J.","family":"Ramsey","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tufts University School of Medicine\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"},{"name":"Division of Ophthalmology, Department of Surgery, UMass Chan\u2014Lahey School of Medicine, 31 Burlington Mall Rd, Burlington, MA 01805, USA"},{"name":"Department of Biomedical Sciences and Disease, New England College of Optometry, 424 Beacon St, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"P71","DOI":"10.1016\/j.ophtha.2020.10.022","article-title":"American Academy of Ophthalmology Preferred Practice Pattern Glaucoma Panel. 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