{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:26:51Z","timestamp":1770834411689,"version":"3.50.1"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Isolated, confined, and extreme environments hold the opportunity to collect unique biomedical data. These often-remote places present specific medical challenges for deployed expeditioners. Here we report a case of acute severe high altitude pulmonary oedema (HAPE) and its management at a remote research station in Antarctica. At the beginning of the 2023 summer campaign at Concordia Station (3200 m AMSL), a technician presented with shortness of breath and compromised circulation three days after arrival on site. Immediate diagnostics and medical treatments with high-flow oxygen and the use of a mobile hyperbaric chamber after initial resuscitation were administered. Within a time window of 24 h, evacuation to sea level was organised via aircraft (flight duration 4 h, non-pressurised cabin) inside the mobile hyperbaric chamber. The patient was discharged from medical treatment 48 h later in Christchurch (NZ). We conclude that despite rigorous pre-deployment screening, even experienced expeditioners can develop critical medical conditions that require prompt reaction and rescue. Structured assessment tools can aid in their recognition and management.<\/jats:p>","DOI":"10.3390\/life16020313","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:45:36Z","timestamp":1770831936000},"page":"313","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe HAPE in a Remote High-Altitude Research Station in Antarctica"],"prefix":"10.3390","volume":"16","author":[{"given":"Fanny","family":"Larcher","sequence":"first","affiliation":[{"name":"French Polar Institute Paul-\u00c9mile Victor (IPEV), 29280 Plouzan\u00e9, France"},{"name":"Terres Australes et Antarctiques Fran\u00e7aises (TAAF), 97410 Saint-Pierre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Laforet","sequence":"additional","affiliation":[{"name":"French Polar Institute Paul-\u00c9mile Victor (IPEV), 29280 Plouzan\u00e9, France"},{"name":"Terres Australes et Antarctiques Fran\u00e7aises (TAAF), 97410 Saint-Pierre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephane","family":"Fraize","sequence":"additional","affiliation":[{"name":"French Polar Institute Paul-\u00c9mile Victor (IPEV), 29280 Plouzan\u00e9, France"},{"name":"Terres Australes et Antarctiques Fran\u00e7aises (TAAF), 97410 Saint-Pierre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Lecca","sequence":"additional","affiliation":[{"name":"Programma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0291-7272","authenticated-orcid":false,"given":"Riccardo","family":"Scipinotti","sequence":"additional","affiliation":[{"name":"Programma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca Bianchi","family":"Fasani","sequence":"additional","affiliation":[{"name":"Programma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Vagnoni","sequence":"additional","affiliation":[{"name":"Programma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8298-1663","authenticated-orcid":false,"given":"Sascha","family":"Freigang","sequence":"additional","affiliation":[{"name":"European Space Agency (ESA), French Polar Institute Paul-\u00c9mile Victor (IPEV), Department of Neurosurgery, Medical University Graz, 8010 Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hundt, N., Apel, C., Bertsch, D., Cerfontaine, C., van der Giet, M., van der Giet, S., Gra\u00df, M., Haunolder, M., Heussen, N.M., and J\u00e4ger, J. 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