{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T11:01:42Z","timestamp":1771844502213,"version":"3.50.1"},"reference-count":23,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:00:00Z","timestamp":1771632000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Minimally invasive surgical therapies (MISTs), such as Rez\u016bm\u2122 Water Vapor Therapy, are emerging treatment options for benign prostatic obstruction (BPO). When prostate cancer is subsequently diagnosed, radical prostatectomy may still be indicated. However, evidence regarding intraoperative challenges and the surgical and functional outcomes of robot-assisted radical prostatectomy (RARP) following Rez\u016bm remains limited. We report the first documented case of RARP following Rez\u016bm in a 68-year-old man. He initially underwent Rez\u016bm for symptomatic BPO. Due to rising PSA, a suspicious lesion on MRI, and a biopsy-confirmed high-risk prostate carcinoma, radical surgery was performed. Intraoperatively, dense fibrosis and altered tissue planes required precise dissection and a level 2 bilateral nerve-sparing approach. A systematic review revealed no previously published cases of RARP after Rez\u016bm. On the other hand, RARP after transurethral resection of the prostate (TURP) is associated with increased operative time, blood loss, and bladder neck reconstruction, though late continence and biochemical recurrence rates are similar to those in treatment-na\u00efve patients. In conclusion, RARP after ablative BPO therapies is feasible but may present unique technical challenges. Larger prospective studies are needed to develop standardized management strategies.<\/jats:p>","DOI":"10.3390\/life16020362","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T10:00:52Z","timestamp":1771840852000},"page":"362","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Robot-Assisted Radical Prostatectomy After Rez\u016bm: A Case Report and Literature Review"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9585-0347","authenticated-orcid":false,"given":"Kosta","family":"Cerovi\u0107","sequence":"first","affiliation":[{"name":"Department of Urology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"},{"name":"Department of Surgery, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5784-1754","authenticated-orcid":false,"given":"Simon","family":"Hawlina","sequence":"additional","affiliation":[{"name":"Department of Urology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia"},{"name":"Department of Surgery, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kaltsas, A., Giannakodimos, I., Symeonidis, E.N., Deligiannis, D., Stavropoulos, M., Symeonidis, A., Adamos, K., Kratiras, Z., Andreou, A., and Chrisofos, M. 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