{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:19:40Z","timestamp":1785406780640,"version":"3.56.0"},"reference-count":33,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006749","name":"Burapha University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006749","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/01ff74m36","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/000025p04","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006749","name":"National Science Research and Innovation Fund","doi-asserted-by":"publisher","award":["2\/2567"],"award-info":[{"award-number":["2\/2567"]}],"id":[{"id":"10.13039\/501100006749","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Lung vibration is a chest physiotherapy technique used to facilitate sputum mobilization and improve airway clearance; however, its effectiveness may vary due to therapist-dependent factors. This study developed a lung vibration device and evaluated its effectiveness in patients with sputum retention. Twenty-five patients, aged \u226518 years with sputum retention, including those with bronchiectasis, pneumonia, and COPD-related conditions, participated in a randomized crossover trial and received two single interventions in random order: a conventional intervention (manual percussion, manual vibration, and suction) and an experimental intervention (manual vibration replaced by the device). Sputum volume and quality, rating of perceived dyspnea (RPD), peripheral oxygen saturation (SpO2), cardiovascular dynamics, respiratory rate, and body temperature were assessed before and immediately after each intervention. Sputum volume was significantly higher following the experimental intervention compared with the conventional intervention (p = 0.010). No significant between-intervention differences were observed in sputum quality, RPD, SpO2, cardiovascular parameters, respiratory rate, or body temperature (all p &gt; 0.05). No potential adverse effects were reported. These findings suggest that the lung vibration device enhances sputum clearance in the short term, with no immediate adverse physiological effects observed, and may serve as a practical alternative to manual vibration.<\/jats:p>","DOI":"10.3390\/life16050794","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T02:32:28Z","timestamp":1779676348000},"page":"794","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness and Physiological Safety of a Lung Vibration Device for Airway Clearance in Patients with Sputum Retention: A Randomized Crossover Study"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3452-3112","authenticated-orcid":false,"given":"Tadsawiya","family":"Padkao","sequence":"first","affiliation":[{"name":"Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamolthip","family":"Channak","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Namphong Hospital, Khon Kaen 40140, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panupich","family":"Kheunkhieo","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Faculty of Engineering, Rajamangala University of Technology Isan, Khon Kaen Campus, Khon Kaen 40000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pimonpan","family":"Taweekarn","sequence":"additional","affiliation":[{"name":"Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6036-0874","authenticated-orcid":false,"given":"Kunavut","family":"Vannajak","sequence":"additional","affiliation":[{"name":"Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orachorn","family":"Boonla","sequence":"additional","affiliation":[{"name":"Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8859-3899","authenticated-orcid":false,"given":"Jatuporn","family":"Phoemsapthawee","sequence":"additional","affiliation":[{"name":"Department of Sports Science, Faculty of Sports and Health Science, Kasetsart University, Nakhon Pathom 73140, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2652-4622","authenticated-orcid":false,"given":"Piyapong","family":"Prasertsri","sequence":"additional","affiliation":[{"name":"Faculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/cc6830","article-title":"Clinical review: Airway hygiene in the intensive care unit","volume":"12","author":"Jelic","year":"2008","journal-title":"Crit. 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