{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:16:40Z","timestamp":1785428200005,"version":"3.56.0"},"reference-count":36,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan","award":["AP23487763"],"award-info":[{"award-number":["AP23487763"]}]},{"award":["AP23487763"],"award-info":[{"award-number":["AP23487763"]}],"id":[{"id":"https:\/\/ror.org\/05tyne317","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Placenta accreta spectrum (PAS) is associated with substantial intraoperative hemorrhage. Abdominal aortic balloon occlusion (AABO) has been introduced to mitigate blood loss, though its benefit remains debated. This study, registered at ClinicalTrials.gov (NCT06721182), assessed maternal outcomes in women with PAS undergoing cesarean delivery managed either with abdominal aortic balloon occlusion or standard surgical care alone. The study (n = 65) and control (n = 75) groups were randomly assigned. Primary outcomes were estimated intraoperative blood loss and transfusion requirements. Secondary outcomes included operative time, hysterectomy, intensive care unit (ICU) admission, length of hospitalization, and complications. Management with AABO was associated with a reduction in estimated intraoperative blood loss (1433.08 \u00b1 1064.97 mL for AABO vs. 2213.33 \u00b1 1574.06 mL in control) and lower transfusion requirements (687.48 \u00b1 979.23 mL for AABO vs. 1161.84 \u00b1 1140.33 mL in control). The incidence of hysterectomy was lower among patients managed with AABO; while this difference was not statistically significant, it was regarded as clinically important. No significant differences were observed in ICU admission rates, duration of hospital stay, or operative time. Procedure-related complications were observed. AABO was associated with lower perioperative blood loss and transfusion requirements, without an increase in overall complications.<\/jats:p>","DOI":"10.3390\/life16071106","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T10:04:44Z","timestamp":1782986684000},"page":"1106","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Abdominal Aorta Balloon Occlusion Versus Standard Care in Placenta Accreta Spectrum Disorder: A Randomized Controlled Trial"],"prefix":"10.3390","volume":"16","author":[{"given":"Gauri","family":"Bapayeva","sequence":"first","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9196-1496","authenticated-orcid":false,"given":"Meruyert","family":"Abdukassimova","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, Nazarbayev University, Astana Z05P3Y4, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4309-0432","authenticated-orcid":false,"given":"Nazira","family":"Kadroldinova","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine, Nazarbayev University, Astana Z05P3Y4, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuat","family":"Kassymbek","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlygash","family":"Togyzbayeva","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyazzat","family":"Saidildina","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2458-8086","authenticated-orcid":false,"given":"Viktor","family":"Zemlyanskiy","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Radiology and Nuclear Medicine, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6641-2366","authenticated-orcid":false,"given":"Kuanysh","family":"Balgynbayev","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Anaesthesiology and Intensive Care, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariya","family":"Usseyeva","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Pathology, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2868-4497","authenticated-orcid":false,"given":"Gulzhanat","family":"Aimagambetova","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"},{"name":"Department of Surgery, School of Medicine, Nazarbayev University, Astana Z05P3Y4, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3914-5154","authenticated-orcid":false,"given":"Milan","family":"Terzic","sequence":"additional","affiliation":[{"name":"Clinical Academic Department of Women\u2019s Health, Corporate Fund University Medical Center, Astana Z05G9F0, Kazakhstan"},{"name":"Department of Surgery, School of Medicine, Nazarbayev University, Astana Z05P3Y4, Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2192853","DOI":"10.1080\/14767058.2023.2192853","article-title":"Association between Short Inter-Pregnancy Interval and Placenta Previa and Placenta Accreta Spectrum with Respect to Maternal Age at First Cesarean Delivery","volume":"36","author":"Liang","year":"2023","journal-title":"J. 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Obstet."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/16\/7\/1106\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T10:51:23Z","timestamp":1782989483000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/16\/7\/1106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,2]]},"references-count":36,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["life16071106"],"URL":"https:\/\/doi.org\/10.3390\/life16071106","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,2]]}}}