{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:06:25Z","timestamp":1789103185115,"version":"build-2803163510"},"reference-count":72,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Guangdong Natural Science Foundation","doi-asserted-by":"crossref","award":["2023A1515012102"],"award-info":[{"award-number":["2023A1515012102"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100010226","name":"Department of Education of Guangdong Province","doi-asserted-by":"publisher","award":["2022KQNCX078"],"award-info":[{"award-number":["2022KQNCX078"]}],"id":[{"id":"10.13039\/501100010226","id-type":"DOI","asserted-by":"publisher"}]},{"award":["2022KQNCX078"],"award-info":[{"award-number":["2022KQNCX078"]}],"id":[{"id":"https:\/\/ror.org\/01s5gyw91","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Colletotrichum higginsianum (Ch) is a typical hemibiotrophic ascomycetous fungus. The diseases it causes often lead to considerable economic losses in global cruciferous crop production. However, current knowledge is still insufficient for us to gain a deeper understanding of how host plants respond at the transcriptional level during Ch infection. Herein, we performed transcriptomic and metabolic assays between Mock and Ch- infected samples. The results showed that Ch infection significantly inhibited the shoot fresh weight and primary root length of host plants. Furthermore, gene ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways related to phenylpropanoid metabolism were highly enriched. Defense hormone salicylic acid (SA) and three metabolites belonging to the phenylpropanoid metabolism pathway were identified. Meanwhile, we screened 5 related enzyme-encoding genes and 78 transcription factors (TFs). Five WRKY, three MYB, and two NAC TFs showed significant expression changes and high correlation with enzyme genes. Our results enrich regulatory networks in crucifier pathogen responses. This work provides potential molecular candidates to support subsequent studies on the mechanisms underlying Ch resistance.<\/jats:p>","DOI":"10.3390\/life16091505","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T09:24:02Z","timestamp":1788945842000},"page":"1505","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcriptomic and Metabolomic Analyses Reveal the Phenylpropanoid Metabolism Regulatory Network in Arabidopsis Response to Colletotrichum higginsianum Infection"],"prefix":"10.3390","volume":"16","author":[{"given":"Hong","family":"Ye","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiwen","family":"Gao","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjian","family":"Zou","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengnv","family":"Liao","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bi-Er","family":"Lai","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyang","family":"Din","sequence":"additional","affiliation":[{"name":"College of Life Sciences, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shanghai Normal University, Shanghai 200234, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuhua","family":"Gu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoyun","family":"You","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1574-6254","authenticated-orcid":false,"given":"Yukun","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region; College of Biology and Agriculture, Shaoguan University, Shaoguan 512005, China"},{"name":"Guangdong Provincial Engineering and Technology Research Center of Special Fruit and Vegetables in Northern Region; Engineering and Technology Research Center of Shaoguan Horticulture in Shaoguan University, Shaoguan University, Shaoguan 512005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1094\/MPMI-10-22-0204-A","article-title":"Genomic resources of four Colletotrichum species (C. fioriniae, C. chrysophilum, C. noveboracense, and C. nupharicola) threatening commercial apple production in the eastern United States","volume":"36","author":"Khodadadi","year":"2023","journal-title":"Mol. 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