{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T02:56:37Z","timestamp":1787280997949,"version":"build-2736575974"},"reference-count":38,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fund \u201cScientific Research\u201d, Ministry of Education and Science of Bulgaria","award":["\u041a\u041e\u0421\u0422 01\/24-2017"],"award-info":[{"award-number":["\u041a\u041e\u0421\u0422 01\/24-2017"]}]},{"name":"Ministry of Economy and Competitively of Spain","award":["RTI2018-096328-B-I00"],"award-info":[{"award-number":["RTI2018-096328-B-I00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>A second-generation poly(propylene imine) dendrimer modified with acridine and its Cu(II) complex have been synthesized for the first time. It has been found that two copper ions form complexes with the nitrogen atoms of the dendrimeric core by coordinate bonds. The new compounds have been characterized by nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), fourier-transform infrared spectroscopy (FTIR) and fluorescence spectroscopy. The spectral characteristics of the modified dendrimer have been measured in different organic solvents, and a negative fluorescence solvatochromism has been observed. The antimicrobial activity of the dendrimers has been tested against model pathogenic microorganisms in agar and by broth dilution method. The cotton fabric treated with both dendrimers has been evaluated towards pathogenic microorganisms. The obtained modified cotton fabrics have been shown to hamper bacterial growth and to prevent biofilm formation. Dendrimer cytotoxicity has been investigated in vitro in the model HEp-2 cell line.<\/jats:p>","DOI":"10.3390\/ma12183020","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T04:26:46Z","timestamp":1568780806000},"page":"3020","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["New Poly(Propylene Imine) Dendrimer Modified with Acridine and Its Cu(II) Complex: Synthesis, Characterization and Antimicrobial Activity"],"prefix":"10.3390","volume":"12","author":[{"given":"Paula","family":"Bosch","sequence":"first","affiliation":[{"name":"Institute of Science and Technology of Polymers, Institute of Science and Technology of Polymers-Spanish National Research Council (ICTP-CSIC), Juan de la Cierva 3, 28006 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desislava","family":"Staneva","sequence":"additional","affiliation":[{"name":"Department of Chemical Technology, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgenia","family":"Vasileva-Tonkova","sequence":"additional","affiliation":[{"name":"The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2788-382X","authenticated-orcid":false,"given":"Petar","family":"Grozdanov","sequence":"additional","affiliation":[{"name":"The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivanka","family":"Nikolova","sequence":"additional","affiliation":[{"name":"The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rositsa","family":"Kukeva","sequence":"additional","affiliation":[{"name":"Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radostina","family":"Stoyanova","sequence":"additional","affiliation":[{"name":"Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7204-8183","authenticated-orcid":false,"given":"Ivo","family":"Grabchev","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Sofia University \u201cSt. Kliment Ohridski\u201d, 1407 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.progsurf.2016.09.001","article-title":"Antibacterial surface design - Contact kill","volume":"91","author":"Kaur","year":"2016","journal-title":"Prog. 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