{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:47:09Z","timestamp":1760237229585,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T00:00:00Z","timestamp":1584576000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The resulting inflammatory reaction to polyethylene (PE) wear debris, which may result in osteolysis, is still considered to be a main reason for aseptic loosening. In addition to the primary wear in hip joint replacements caused by head-insert articulation, relative motions between the PE liner and the metal cup may cause additional wear. In order to limit this motion, various locking mechanisms were used. We investigated three different locking mechanisms (Aesculap, DePuy, and Zimmer Biomet) to address the resulting relative motion between the acetabular cup and PE liner and the maximum disassembly force. A standardized setting with increasing load levels was used in combination with optically based three-dimensional measurements. In addition the maximum disassembly forces were evaluated according to the ASTM F1820-13 standard. Our data showed significant differences between the groups, with a maximum relative motion at the maximum load level (3.5 kN) of 86.5 \u00b1 32.7 \u00b5m. The maximum axial disassembly force was 473.8 \u00b1 94.6 N. The in vitro study showed that various locking mechanisms may influence cup-inlay stability.<\/jats:p>","DOI":"10.3390\/ma13061392","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T10:01:35Z","timestamp":1584612095000},"page":"1392","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of Different Locking Mechanisms in Total Hip Arthroplasty: Relative Motion between Cup and Inlay"],"prefix":"10.3390","volume":"13","author":[{"given":"Sebastian","family":"Jaeger","sequence":"first","affiliation":[{"name":"Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg University, 69118 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3519-9307","authenticated-orcid":false,"given":"Maximilian","family":"Uhler","sequence":"additional","affiliation":[{"name":"Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg University, 69118 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9942-3681","authenticated-orcid":false,"given":"Stefan","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg University, 69118 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2415-3274","authenticated-orcid":false,"given":"Nicholas A.","family":"Beckmann","sequence":"additional","affiliation":[{"name":"Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg University, 69118 Heidelberg, Germany"},{"name":"Department of Orthopaedic Surgery and Traumatology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Braun","sequence":"additional","affiliation":[{"name":"Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg University, 69118 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1136\/ard.56.8.455","article-title":"Total hip replacement: Indications for surgery and risk factors for failure","volume":"56","author":"Crawford","year":"1997","journal-title":"Ann. Rheum. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1016\/S0140-6736(12)60607-2","article-title":"Hip arthroplasty","volume":"380","author":"Pivec","year":"2012","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1302\/0301-620X.100B7.BJJ-2017-1603.R1","article-title":"Ten-year survivorship of primary total hip arthroplasty in patients 30 years of age or younger","volume":"100-B","author":"Makarewich","year":"2018","journal-title":"Bone Jt. J."},{"key":"ref_4","first-page":"182","article-title":"Biologic effects of implant debris","volume":"67","author":"Hallab","year":"2009","journal-title":"Bull. NYU Hosp. Jt. Dis."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1054\/arth.2002.33664","article-title":"A literature review of the association between wear rate and osteolysis in total hip arthroplasty","volume":"17","author":"Dumbleton","year":"2002","journal-title":"J. Arthroplast."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00003086-200112000-00007","article-title":"Wear and periprosthetic osteolysis: The problem","volume":"393","author":"Harris","year":"2001","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cis.2014.09.001","article-title":"Interactions between mammalian cells and nano- or micro-sized wear particles: Physico-chemical views against biological approaches","volume":"213","author":"Prokopovich","year":"2014","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.arth.2010.07.012","article-title":"Minimal backside surface changes observed in retrieved acetabular liners","volume":"26","author":"Akbari","year":"2011","journal-title":"J. Arthroplast."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.actbio.2018.10.045","article-title":"Backside wear in acetabular hip joint replacement","volume":"83","author":"Braun","year":"2019","journal-title":"Acta Biomater."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1007\/s00132-012-1948-1","article-title":"Grundlagen zur tribologischen analyse von endoprothesen","volume":"41","author":"Kretzer","year":"2012","journal-title":"Der Orthop\u00e4de"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"5049","DOI":"10.1016\/j.biomaterials.2007.07.040","article-title":"The lexicon of polyethylene wear in artificial joints","volume":"28","author":"McKellop","year":"2007","journal-title":"Biomaterials"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0021-9290(98)00030-X","article-title":"Backside nonconformity and locking restraints affect liner\/shell load transfer mechanisms and relative motion in modular acetabular components for total hip replacement","volume":"31","author":"Kurtz","year":"1998","journal-title":"J. Biomech."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.arth.2005.04.039","article-title":"Factors influencing the initial micromotion between polyethylene acetabular cups and titanium alloy shells","volume":"21","author":"Kyle","year":"2006","journal-title":"J. Arthroplast."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0883-5403(97)90043-7","article-title":"Fixation of ultrahigh-molecular-weight polyethylene liners to metal-backed acetabular cups","volume":"12","author":"Williams","year":"1997","journal-title":"J. Arthroplast."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.actbio.2019.07.050","article-title":"Backside wear, particle migration and effectiveness of screw hole plugs in acetabular hip joint replacement with cross-linked polyethylene","volume":"97","author":"Braun","year":"2019","journal-title":"Acta Biomater."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1302\/2046-3758.74.BJR-2017-0198.R1","article-title":"Comparison of the stability of three fixation techniques between porous metal acetabular components and augments","volume":"7","author":"Beckmann","year":"2018","journal-title":"Bone Jt. Res."},{"key":"ref_17","unstructured":"ASTM F1820-13 (2013). Standard Test Method for Determining the Forces for Disassembly of Modular Acetabular Devices, ASTM International."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00003086-199702000-00020","article-title":"Pelvic lysis and polyethylene wear at 5-8 years in an uncemented total hip","volume":"335","author":"Barrack","year":"1997","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s11999-015-4471-y","article-title":"Backside wear is not dependent on the acetabular socket design in crosslinked polyethylene liners","volume":"474","author":"Bali","year":"2016","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.arth.2005.01.025","article-title":"Impingement contributes to backside wear and screw-metallic shell fretting in modular acetabular cups","volume":"22","author":"Kligman","year":"2007","journal-title":"J. Arthroplast."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0883-5403(96)80116-1","article-title":"Wear of the polyethylene liner-metallic shell interface in modular acetabular components. An in vitro analysis","volume":"11","author":"Lieberman","year":"1996","journal-title":"J. Arthroplast."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.arth.2005.04.033","article-title":"The acetabular insert-metal backing interface: An additional source of polyethylene wear debris","volume":"20","author":"Wasielewski","year":"2005","journal-title":"J. Arthroplast."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00003086-199311000-00028","article-title":"A comparison of the disassociation strength of modular acetabular components","volume":"296","author":"Tradonsky","year":"1993","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_24","first-page":"802753","article-title":"Acetabular liner dissociation following total hip arthroplasty: A rare but serious complication that may be easily misinterpreted in the emergency department","volume":"2015","author":"Napier","year":"2015","journal-title":"Case Rep. Emerg. Med."},{"key":"ref_25","first-page":"8687131","article-title":"Backside wear analysis of retrieved acetabular liners with a press-fit locking mechanism in comparison to wear simulation in vitro","volume":"2016","author":"Jager","year":"2016","journal-title":"BioMed Res. Int."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.artd.2017.11.009","article-title":"Early aseptic loosening of the tritanium primary acetabular component with screw fixation","volume":"4","author":"Long","year":"2018","journal-title":"Arthroplast. Today"}],"container-title":["Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1996-1944\/13\/6\/1392\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:09:41Z","timestamp":1760173781000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1996-1944\/13\/6\/1392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,19]]},"references-count":26,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,3]]}},"alternative-id":["ma13061392"],"URL":"https:\/\/doi.org\/10.3390\/ma13061392","relation":{},"ISSN":["1996-1944"],"issn-type":[{"type":"electronic","value":"1996-1944"}],"subject":[],"published":{"date-parts":[[2020,3,19]]}}}