{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:55:52Z","timestamp":1781661352893,"version":"3.54.5"},"reference-count":56,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>After tooth extraction, the alveolar bone undergoes a physiological resorption that may compromise the future placement of the implant in its ideal position. This study evaluated bone density, morphological changes, and histomorphometric results undergone by alveolar bone after applying a new biomaterial composed of calcium phosphate modified with silicon (CAPO-Si) compared with hydroxyapatite of bovine origin (BHA). Alveolar ridge preservation (ARP) was performed in 24 alveoli, divided into a test group filled with CAPO-Si and a control group filled with BHA. Three months later, the mineral bone density obtained by the biomaterials, horizontal and vertical bone loss, the degree of alveolar corticalization, and histomorphometric results were evaluated. Both biomaterials presented similar behavior in terms of densitometric results, vertical bone loss, and degree of alveolar corticalization. Alveoli treated with CAPO-Si showed less horizontal bone loss in comparison with alveoli treated with BHA (0.99 \u00b1 0.2 mm vs. 1.3 \u00b1 0.3 mm), with statistically significant difference (p = 0.017). Histomorphometric results showed greater bone neoformation in the test group than the control group (23 \u00b1 15% vs. 11 \u00b1 7%) (p = 0.039) and less residual biomaterial (5 \u00b1 10% vs. 17 \u00b1 13%) (p = 0.043) with statistically significant differences. In conclusion, the ARP technique obtains better results with CAPO-Si than with BHA.<\/jats:p>","DOI":"10.3390\/ma14040940","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T04:49:01Z","timestamp":1613537341000},"page":"940","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Calcium Phosphate Modified with Silicon vs. Bovine Hydroxyapatite for Alveolar Ridge Preservation: Densitometric Evaluation, Morphological Changes and Histomorphometric Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6060-7299","authenticated-orcid":false,"given":"Guillermo","family":"Cadenas-Vacas","sequence":"first","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Mart\u00ednez-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0966-3276","authenticated-orcid":false,"given":"Cristina","family":"Barona-Dorado","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0330-6959","authenticated-orcid":false,"given":"Luis","family":"S\u00e1nchez-Labrador","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1701-8867","authenticated-orcid":false,"given":"Jorge","family":"Cort\u00e9s-Bret\u00f3n Brinkmann","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2435-8766","authenticated-orcid":false,"given":"Cristina","family":"Meniz-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6488-9265","authenticated-orcid":false,"given":"Jos\u00e9 Mar\u00eda","family":"Mart\u00ednez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Dental Clinical Specialities, Faculty of Dentistry, Complutense University of Madrid (UCM), Plaza Ramon y Cajal S\/N, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/jbm.a.31383","article-title":"Effect of rapidly resorbable bone substitute materials on the temporal expression of the osteoblastic phenotype in vitro","volume":"84","author":"Knabe","year":"2008","journal-title":"J. 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