{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:58:48Z","timestamp":1760234328921,"version":"build-2065373602"},"reference-count":23,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T00:00:00Z","timestamp":1620691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Analysis of short-term results regarding dimensional stability of post-extraction sockets managed via a preservation protocol using deproteinized bovine bone matrix and a xenogeneic collagen matrix. Materials and methods Fifteen patients needing extraction of one single-rooted premolar tooth were treated in a pilot study. Five patients were treated in each centre. After tooth extraction, sockets were filled with anorganic bovine bone matrix and covered with a xenogeneic collagen matrix. Six months later, implants were placed. Dimensional changes in the treated sites were digitally evaluated using the best-fit superimposition of pre-and post-socket preservation models. Results After six months of healing, the vertical reduction of the grafted sites was 0.31 \u00b1 0.24 mm (p &lt; 0.001). Volumetric analysis of superimposed models showed an average palatal-lingual contraction of 0.33 \u00b1 0.51 mm3 (p = 0.02). At the vestibular level, the average contraction was found to be 0.8 \u00b1 0.3 mm3 (p &lt; 0.001). Finally, the analysis of linear variations in the treated sites on a single sagittal section at the crystal level, and at 3 and 7 mm apically respect to the crest, both towards the vestibule and palate, generally showed more marked resorption at the crestal level compared to apical measurements. Conclusion: The clinical protocol herein employed for socket preservation showed a positive effect in preventing the physiological post-extraction remodeling.<\/jats:p>","DOI":"10.3390\/ma14102473","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T11:30:16Z","timestamp":1620732616000},"page":"2473","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Healing of Post-Extraction Sockets Filled with Anorganic Bovine Bone and Covered with a Xenogeneic Collagen Matrix. Radiological 2D and 3D Results of a Pilot Study to Assess Dimensional Stability"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7901-8120","authenticated-orcid":false,"given":"Tiziano","family":"Testori","sequence":"first","affiliation":[{"name":"Dental Clinic, IRCCS Orthopedic Institute Galeazzi, 20161 Milan, Italy"},{"name":"Department of Periodontics and Oral Medicine, School of Dentistry, The University of Michigan, Ann Arbor, MI 58259, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo Antonio","family":"Deflorian","sequence":"additional","affiliation":[{"name":"Section of Implantology and Oral Rehabilitation, Dental Clinic, IRCCS Orthopedic Institute Galeazzi, 20161 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Mandelli","sequence":"additional","affiliation":[{"name":"Dental School, Vita-Salute University, IRCCS San Raffaele, 20132 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Attardo","sequence":"additional","affiliation":[{"name":"Center for Edentulism and Jawbone Atrophies, Fondazione IRCCS C\u00e0 Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Maiorana","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy"},{"name":"Dental Clinic, Fondazione IRCCS C\u00e0 Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-0984","authenticated-orcid":false,"given":"Massimo","family":"Del Fabbro","sequence":"additional","affiliation":[{"name":"Dental Clinic, IRCCS Orthopedic Institute Galeazzi, 20161 Milan, Italy"},{"name":"Department of Biomedical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"Vinci","sequence":"additional","affiliation":[{"name":"Graduate school of oral surgery, Dental School, Vita-Salute University, 20132 Milan, Italy"},{"name":"Department of Dentistry, IRCCS San Raffaele, 20132 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1034\/j.1600-051X.2003.00366.x","article-title":"Dynamics of bone tissue formation in tooth extraction sites. 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