{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:08:38Z","timestamp":1791284918023,"version":"4.1.0"},"reference-count":44,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T00:00:00Z","timestamp":1648252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The mucocele is the most common minor salivary gland associated disease of the oral cavity. It is also considered one of the most common biopsied oral lesions in pediatric patients. In recent years, extensive evidence has been published about the usage of lasers in treating mucoceles in pediatric patients. The aim of the present study was to assess the effectiveness of laser irradiation in the treatment of pediatric mucocele. An electronic search of databases (PubMed, Scopus, Web of Science and Google Scholar) was carried out in order to identify all relevant articles using a combination of the following keywords: \u201cPediatric\u201d, \u201cOral\u201d, \u201cMucocele\u201d, \u201cDental\u201d, \u201cOral Medicine\u201d, \u201cSoft Dental Lasers\u201d, \u201cHard Dental Lasers\u201d, and \u201cLasers,\u201d for all case reports, case series, case-control and cohort studies published from 2007 to 2021. After limiting the search results, removing duplicate titles, and eligibility evaluation, 17 papers were enrolled in the study. Out of the total studies included, 10 articles were related to the diode (635 nm, 808 nm, 810 nm, and 980 nm), 5 to CO2 (10,600 nm), 3 to Er, Cr: YSGG (2780 nm), and 1 involving KTP lasers (532 nm). All studies indicated successful clinical results on mucocele excision with better intra- and post-operative indicators. The general characteristics and outcomes were summarized, and the quality of the studies was assessed using CARE guidelines in this systematic review. The reduction or absence of pain and bleeding, hemostasis, reduced operating time, minimal analgesic consumption, and an antibacterial effect were among the advantages of laser irradiation in the included studies. The laser has proven itself to play an effective role in the treatment of oral mucocele in paediatric patients.<\/jats:p>","DOI":"10.3390\/ma15072452","type":"journal-article","created":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T21:29:36Z","timestamp":1648416576000},"page":"2452","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Effectiveness of Lasers in Treatment of Oral Mucocele in Pediatric Patients: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3874-8490","authenticated-orcid":false,"given":"Muhammad Shahrukh Khan","family":"Sadiq","sequence":"first","affiliation":[{"name":"Department of Oral Pathology, Bahria University Dental College, Karachi 07557, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsheen","family":"Maqsood","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, Bahria University Dental College, Karachi 07557, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatema","family":"Akhter","sequence":"additional","affiliation":[{"name":"Department of Surgical and Diagnostic Sciences, College of Dentistry, Dar Al Uloom University, Riyadh 13314, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7131-1752","authenticated-orcid":false,"given":"Mohammad Khursheed","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2050-0988","authenticated-orcid":false,"given":"Maria Shakoor","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Altamash Institute of Dental Medicine, Karachi 75500, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheheryar","family":"Minallah","sequence":"additional","affiliation":[{"name":"Dental Department, Jinnah Postgraduate Medical Centre, Karachi 75510, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4682-3163","authenticated-orcid":false,"given":"Fahim","family":"Vohra","sequence":"additional","affiliation":[{"name":"Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4387-7959","authenticated-orcid":false,"given":"Haytham Jamil","family":"Alswairki","sequence":"additional","affiliation":[{"name":"School of Dental Sciences, Universiti Sains Malaysia, Kota Bharu 16150, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huda","family":"Abutayyem","sequence":"additional","affiliation":[{"name":"Center of Medical and Bio-Allied Health Sciences Research, Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman P.O. Box 346, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Mussallam","sequence":"additional","affiliation":[{"name":"Private Clinic, Dubai P.O. Box 65882, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0960-1123","authenticated-orcid":false,"given":"Naseer","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Altamash Institute of Dental Medicine, Karachi 75500, Pakistan"},{"name":"Prosthodontics Unit, School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kota Bharu 16150, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Hayashida, A.M., Zerbinatti, D.C., Balducci, I., Cabral, L.A.G., and Almeida, J.D. (2010). 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