{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:02:45Z","timestamp":1787169765929,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Porous tantalum has been extensively used in orthopaedic surgery, including uncemented total knee arthroplasty (TKA). Favourable results were reported with earlier monobloc tibial components and the design evolved to modular implants. We aimed to analyse possible causes for extensive medial tibia bone loss, resulting in modular porous tantalum tibia baseplate fracture after primary TKA. Retrieved tissue samples were scanned with 3 MeV focused proton beam for Proton-Induced X-ray Emission (micro-PIXE) elemental analysis. Fractographic and microstructural analysis were performed by stereomicroscopy. A full 3D finite-element model was made for numerical analysis of stress\u2013strain conditions of the tibial baseplate. Histological examination of tissue underneath the broken part of the tibial baseplate revealed dark-stained metal debris, which was confirmed by micro-PIXE to consist of tantalum and titanium. Fractographic analysis and tensile testing showed that the failure of the tibial baseplate fulfilled the criteria of a typical fatigue fracture. Microstructural analysis of the contact surface revealed signs of bone ingrowth in 22.5% of the surface only and was even less pronounced in the medial half of the tibial baseplate. Further studies are needed to confirm the responsibility of metal debris for an increased bone absorption leading to catastrophic tibial tray failure.<\/jats:p>","DOI":"10.3390\/ma15072575","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T21:34:29Z","timestamp":1648762469000},"page":"2575","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Total Knee Replacement with an Uncemented Porous Tantalum Tibia Component: A Failure Analysis"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1902-8447","authenticated-orcid":false,"given":"Samo K.","family":"Fokter","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3276-8431","authenticated-orcid":false,"given":"Nenad","family":"Gubeljak","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Punz\u00f3n-Quijorna","sequence":"additional","affiliation":[{"name":"Department of Low and Medium Energy Physics F2, Jo\u017eef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2469-3342","authenticated-orcid":false,"given":"Primo\u017e","family":"Pelicon","sequence":"additional","affiliation":[{"name":"Department of Low and Medium Energy Physics F2, Jo\u017eef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitja","family":"Kelemen","sequence":"additional","affiliation":[{"name":"Department of Low and Medium Energy Physics F2, Jo\u017eef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Primo\u017e","family":"Vavpeti\u010d","sequence":"additional","affiliation":[{"name":"Department of Low and Medium Energy Physics F2, Jo\u017eef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u017eef","family":"Predan","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luka","family":"Ferli\u010d","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical Engineering, University of Maribor, Smetanova 17, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Novak","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1302\/2633-1462.21.BJO-2020-0172.R1","article-title":"Cementless knee arthroplasty: A review of recent performance","volume":"2","author":"Asokan","year":"2021","journal-title":"Bone Jt. 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