{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:26:35Z","timestamp":1792423595876,"version":"4.5.0"},"reference-count":39,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Background: This investigation aimed to radiographically assess the variations of graft dimension following maxillary sinus augmentation by the lateral approach. Methods: Eighteen patients (seven males), with a mean age at surgery of 66.5 \u00b1 9.8 (range 52\u201382) years, were unilaterally treated. Thirty-five dental implants were positioned in the posterior maxilla simultaneously to grafting with heterologous biomaterials. Intraoral radiographs taken at the time of surgery, after six months, and at the longest follow-up (up to nine years after implant placement) were analyzed. The following distances were measured: mesio-distal width of the graft, vertical distance from implant apex to most coronal level of the graft, distance from the mesial aspect of the (mesial) implant to the mesial graft extension; distance from the distal aspect of the (distal) implant to the distal graft extension, and graft height along the implant axis. The dimensional changes with respect to baseline, after six months and at the longest follow-up were calculated. Results: The patient-based mean follow-up was 38.3 \u00b1 30.1 months (range 12\u2013108 months). The mean residual bone height at the mesial and distal aspect of the implants was 3.19 \u00b1 2.05 mm and 2.65 \u00b1 1.60 mm, respectively (p = 0.38). The mean graft width at baseline was 27.95 \u00b1 5.23 mm, and the mean graft width reduction was 10.2 \u00b1 12.7% (2.98 \u00b1 3.62 mm) and 11.3 \u00b1 14.4% (3.36 \u00b1 4.08 mm) at six months and at the latest follow-up. The change was significant at six months (p = 0.005), but did not show significant further variation (p = 0.11). On the mesial and distal aspect, the mean graft extension decreased by 1.56 \u00b1 2.67 mm and 0.84 \u00b1 2.71 mm at the latest follow-up. No significant difference between mesial and distal changes was found (p = 0.24), suggesting that the biomaterial is resorbed homogeneously on both sides. The mean graft height was 11.92 \u00b1 2.53 mm at baseline and decreased by 9.3 \u00b1 9.05% (1.11 \u00b1 1.09 mm) at six months (p &lt; 0.001). Non-significant further changes were found at the latest follow-up (p = 0.10). Conclusions: after early remodeling, heterologous bone substitutes showed a good dimensional stability in the mid-term for maxillary sinus augmentation.<\/jats:p>","DOI":"10.3390\/ma15093056","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T21:39:45Z","timestamp":1650749985000},"page":"3056","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Radiographic Analysis of Graft Dimensional Changes after Lateral Maxillary Sinus Augmentation with Heterologous Materials and Simultaneous Implant Placement: A Retrospective Study in 18 Patients"],"prefix":"10.3390","volume":"15","author":[{"given":"Luca","family":"Comuzzi","sequence":"first","affiliation":[{"name":"Freelance Researcher, San Vendemmiano, 31020 Conegliano Veneto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Tumedei","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, Universit\u00e0 degli Studi di Milano, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"Piattelli","sequence":"additional","affiliation":[{"name":"Dental School, Saint Camillus International University for Health Sciences (Unicamillus), 00131 Rome, Italy"},{"name":"Dental School, University of Belgrade, 11000 Belgrade, Serbia"},{"name":"Casa di Cura Villa Serena, Citt\u00e0 Sant\u2019Angelo, 65013 Pescara, Italy"},{"name":"Fondazione Villaserena per la Ricerca, Citt\u00e0 Sant\u2019Angelo, 65013 Pescara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Tartaglia","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, Universit\u00e0 degli Studi di Milano, 20122 Milan, Italy"},{"name":"IRCCS Fondazione Ca\u2019Granda IRCCS Ospedale Maggiore Policlinico, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7144-0984","authenticated-orcid":false,"given":"Massimo","family":"Del Fabbro","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences, Universit\u00e0 degli Studi di Milano, 20122 Milan, Italy"},{"name":"IRCCS Orthopedic Institute Galeazzi, Via Riccardo Galeazzi 4, 20161 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/01.id.0000220120.54308.f3","article-title":"Maxillary Sinus Augmentation with Different Biomaterials: A Comparative Histologic and Histomorphometric Study in Man","volume":"15","author":"Scarano","year":"2006","journal-title":"Implant Dent"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2594670","DOI":"10.1155\/2017\/2594670","article-title":"Maxillary Sinus Augmentation with Decellularized Bovine Compact Particles: A Radiological, Clinical, and Histologic Report of 4 Cases","volume":"2017","author":"Scarano","year":"2017","journal-title":"Biomed Res. 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Agents"}],"container-title":["Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1996-1944\/15\/9\/3056\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:58:58Z","timestamp":1760137138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1996-1944\/15\/9\/3056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,22]]},"references-count":39,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["ma15093056"],"URL":"https:\/\/doi.org\/10.3390\/ma15093056","relation":{},"ISSN":["1996-1944"],"issn-type":[{"value":"1996-1944","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,22]]}}}