{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:09:29Z","timestamp":1790129369992,"version":"4.0.1"},"reference-count":21,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T00:00:00Z","timestamp":1684540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science and Technology (Taiwan)","award":["110-2622-8-212-001-TE4"],"award-info":[{"award-number":["110-2622-8-212-001-TE4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>In this study, polyethylene oxide (PEO) and curdlan solutions were used to prepare PEO\/curdlan nanofiber films by electrospinning using deionized water as the solvent. In the electrospinning process, PEO was used as the base material, and its concentration was fixed at 6.0 wt.%. Moreover, the concentration of curdlan gum varied from 1.0 to 5.0 wt.%. For the electrospinning conditions, various operating voltages (12\u201324 kV), working distances (12\u201320 cm) and feeding rates of polymer solution (5\u201350 \u03bcL\/min) were also modified. Based on the experimental results, the optimum concentration for the curdlan gum was 2.0 wt.%. Additionally, the most suitable operating voltage, working distance and feeding rate for the electrospinning process were 19 kV, 20 cm and 9 \u03bcL\/min, respectively, which can help to prepare relatively thinner PEO\/curdlan nanofibers with higher mesh porosity and without the formation of beaded nanofibers. Finally, the PEO\/curdlan nanofiber instant films containing 5.0 wt.% quercetin inclusion complex were used to perform wetting and disintegration processes. It was found that the instant film can be dissolved significantly on the low-moisture wet wipe. On the other hand, when the instant film touched water, it can be disintegrated very quickly within 5 s, and the quercetin inclusion complex was dissolved in water efficiently. Furthermore, when the instant film encountered the water vapor at 50 \u00b0C, it almost completely disintegrated after immersion for 30 min. The results indicate that the electrospun PEO\/curdlan nanofiber film is highly feasible for biomedical applications consisting of instant masks and quick-release wound dressings, even in the water vapor environment.<\/jats:p>","DOI":"10.3390\/ma16103863","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T02:00:27Z","timestamp":1684720827000},"page":"3863","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Preparation and Characteristics of Polyethylene Oxide\/Curdlan Nanofiber Films by Electrospinning for Biomedical Applications"],"prefix":"10.3390","volume":"16","author":[{"given":"Shu-Hung","family":"Lin","sequence":"first","affiliation":[{"name":"PhD Program of Biotechnology and Industry, College of Biotechnology and Bioresources, Da-Yeh University, Changhua 515, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sin-Liang","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Da-Yeh University, Changhua 515, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Ming","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6533-3293","authenticated-orcid":false,"given":"Jane-Yii","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua 515, Taiwan"},{"name":"Biotechnology Research and Development Center, Da-Yeh University, Changhua 515, Taiwan"},{"name":"Innovation Incubation Center, Da-Yeh University, Changhua 515, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5692","DOI":"10.1002\/app.25068","article-title":"Electrospinning of chitosan\/poly(vinyl alchol)\/acrylic acid acrylic solutions","volume":"102","author":"Zhou","year":"2006","journal-title":"J. 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