{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:40:54Z","timestamp":1789908054712,"version":"4.0.1"},"reference-count":53,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010783","name":"Scientific Grant Agency of Ministry of Education, Science and Sport","doi-asserted-by":"publisher","award":["1\/0134\/20"],"award-info":[{"award-number":["1\/0134\/20"]}],"id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010783","name":"Scientific Grant Agency of Ministry of Education, Science and Sport","doi-asserted-by":"publisher","award":["KEGA 016\u017dU-4\/2023"],"award-info":[{"award-number":["KEGA 016\u017dU-4\/2023"]}],"id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Slovak Academy of Sciences","award":["1\/0134\/20"],"award-info":[{"award-number":["1\/0134\/20"]}]},{"name":"Slovak Academy of Sciences","award":["KEGA 016\u017dU-4\/2023"],"award-info":[{"award-number":["KEGA 016\u017dU-4\/2023"]}]},{"name":"Project to support young researchers at UNIZA","award":["1\/0134\/20"],"award-info":[{"award-number":["1\/0134\/20"]}]},{"name":"Project to support young researchers at UNIZA","award":["KEGA 016\u017dU-4\/2023"],"award-info":[{"award-number":["KEGA 016\u017dU-4\/2023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Due to the combination of high corrosion resistance and suitable mechanical properties, AISI 316L stainless steel is extensively used as the biomaterial for surgical implants. However, heat exposure in inappropriate temperatures can cause its sensitization accompanied by chromium depletion along the grain boundaries. This study deals with an assessment of the susceptibility of sensitized AISI 316L biomaterial to pitting under conditions simulating the internal environment of the human body (Hank\u2019s balanced salt solution, 37 \u00b1 0.5 \u00b0C). The resistance to pitting corrosion is tested by the potentiodynamic polarization and by the 50-day exposure immersion test. Corrosion damage after the exposure immersion test is evaluated in the specimens\u2019 cross-sections by optical microscope and SEM. Despite passive behavior in potentiodynamic polarization and shallow, slight corrosion damage observed after exposure, the sensitized AISI 316L biomaterial could represent a risk, especially in long-term implantation even after the chemical removal of high-temperature oxides.<\/jats:p>","DOI":"10.3390\/ma16165714","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T09:07:16Z","timestamp":1692608836000},"page":"5714","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Effect of Sensitization on the Susceptibility of AISI 316L Biomaterial to Pitting Corrosion"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1924-3785","authenticated-orcid":false,"given":"Viera","family":"Zatkal\u00edkov\u00e1","sequence":"first","affiliation":[{"name":"Department of Materials Engineering, Faculty of Mechanical Engineering, University of \u017dilina, Univerzitn\u00e1 8215\/1, 010 26 \u017dilina, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2782-5876","authenticated-orcid":false,"given":"Milan","family":"Uhr\u00ed\u010dik","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, Faculty of Mechanical Engineering, University of \u017dilina, Univerzitn\u00e1 8215\/1, 010 26 \u017dilina, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Markovi\u010dov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, Faculty of Mechanical Engineering, University of \u017dilina, Univerzitn\u00e1 8215\/1, 010 26 \u017dilina, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5341-9292","authenticated-orcid":false,"given":"Lucia","family":"Pastierovi\u010dov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, Faculty of Mechanical Engineering, University of \u017dilina, Univerzitn\u00e1 8215\/1, 010 26 \u017dilina, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2688-1075","authenticated-orcid":false,"given":"Lenka","family":"Kucharikov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, Faculty of Mechanical Engineering, University of \u017dilina, Univerzitn\u00e1 8215\/1, 010 26 \u017dilina, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mser.2014.10.001","article-title":"Metallic implant biomaterials","volume":"87","author":"Chen","year":"2015","journal-title":"Mat. Sci. Eng. R"},{"key":"ref_2","unstructured":"Dharadhar, S., and Majumdar, A.S. (2023, May 15). Biomaterials and Its Medical Applications. Available online: https:\/\/www.researchgate.net\/publication\/337341622_Biomaterials_and_Its_Medical_Applications."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Paul, S. (2019). Application of Biomedical Engineering in Neuroscience, Springer. [1st ed.].","DOI":"10.1007\/978-981-13-7142-4"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4103\/jpbs.JPBS_88_20","article-title":"Review of metallic biomaterials in dental applications","volume":"12","author":"Tharani","year":"2020","journal-title":"J. Pharm. Bioall. Sci."},{"key":"ref_5","unstructured":"Bazaka, O., Bazaka, K., Kingshott, P., Crawford, R.J., and Ivanova, E.P. (2021). The Chemistry of Inorganic Biomaterials, Royal Society of Chemistry."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.matpr.2022.02.501","article-title":"Optimization of electrochemical corrosion behavior of 316L stainless steel as an effective biomaterial for orthopedic applications","volume":"57","author":"Pathote","year":"2022","journal-title":"Mater. Today Proc."},{"key":"ref_7","first-page":"25","article-title":"Stainless Steel Alloys for Dental Application: Corrosion Behaviour in the Presence of Toothpaste Vicco","volume":"9","author":"Souza","year":"2017","journal-title":"Pharma Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.13005\/ojc\/330304","article-title":"Study of the Corrosion Resistance of Type 304L and 316 Austenitic Stainless Steels in Acid Chloride Solution","volume":"33","author":"Loto","year":"2017","journal-title":"Orient. J. Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2298\/CICEQ151127020P","article-title":"The Effects of Passivation Parameters on Pitting Potential of Biomedical Stainless Steel","volume":"23","author":"Petkovic","year":"2017","journal-title":"Chem. Ind. Chem. Eng. Q."},{"key":"ref_10","first-page":"131","article-title":"The influence of molybdenum on corrosion resistance of sintered austenitic stainless steels","volume":"4","year":"2015","journal-title":"Tech. Trans."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1007\/s11665-020-04920-9","article-title":"Effect of Molybdenum on Pit Initiation Rate and Pit Growth Using Electrochemical Noise and Its Correlation with Confocal Laser Scanning Microscopic Studies","volume":"29","author":"Upadhyay","year":"2020","journal-title":"J. Mater. Eng. Perform."},{"key":"ref_12","unstructured":"Kolli, S. (2020). Sensitization in Austenitic Stainless Steels, University of Oulu Faculty of Technology."},{"key":"ref_13","first-page":"133","article-title":"Effect of Sensitization on The Corrosion of Austenitic Stainless Steel in Fresh Water","volume":"13","author":"Okpala","year":"2016","journal-title":"J. Mech. Civ. Eng."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"108","DOI":"10.30657\/pea.2021.27.13","article-title":"Investigation of corrosion rate of X55CrMo14 stainless steel at 65% nitrate acid at 348 K","volume":"27","year":"2021","journal-title":"Prod. Eng. Arch."},{"key":"ref_15","first-page":"2","article-title":"Sensitization of 316L stainless steel made by laser powder bed fusion additive manufacturing","volume":"79","author":"Lou","year":"2023","journal-title":"Corrosion"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Reclaru, L., and Ardelean, L.C. (2020). Corrosion Susceptibility and Allergy Potential of Austenitic Stainless Steels. Materials, 13.","DOI":"10.3390\/ma13184187"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1007\/s11665-014-1018-4","article-title":"Effect of Different Degrees of Sensitization on the EIS Response of 316L and 316 SS in Transpassive Region","volume":"23","author":"Behbahani","year":"2014","journal-title":"JMEPEG"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"McGuire, M.F. (2008). Stainless Steels for Design Engineers, ASM International. [1st ed.].","DOI":"10.31399\/asm.tb.ssde.9781627082860"},{"key":"ref_19","unstructured":"(2023, April 25). Practical Guidelines for the Fabrication of Austenitic Stainless Steels. Available online: https:\/\/www.imoa.info\/download_files\/stainless-steel\/Austenitics_fabrication.pdf."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"104337","DOI":"10.1016\/j.engfailanal.2019.104337","article-title":"Failure analysis of service exposed austenitic stainless steel pipelines","volume":"108","author":"Sreevidya","year":"2020","journal-title":"Eng. Fail. Anal."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.engfailanal.2015.11.011","article-title":"Failure analysis of 316L austenitic stainless steel bellows used under dynamic sodium in a creep testing chamber","volume":"59","author":"Ravi","year":"2016","journal-title":"Eng. Fail. Anal."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.engfailanal.2013.01.044","article-title":"Corrosion behavior analysis of an austenitic stainless steel exposed to fire","volume":"31","author":"Kuri","year":"2013","journal-title":"Eng. Fail. Anal."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.sna.2017.01.017","article-title":"A stainless-steel-based implantable pressure sensor chip and its integration by microwelding","volume":"257","author":"Chen","year":"2017","journal-title":"Sens. Actuator A Phys."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jmrt.2022.09.016","article-title":"Experimental investigation of effect of welding parameters on surface roughness, micro-hardness and tensile strength of AISI 316L stainless steel welded joints using 308L filler material by TIG welding","volume":"2","author":"Ghumman","year":"2022","journal-title":"J. Mater. Res. Technol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"015401","DOI":"10.1088\/2053-1591\/aa9f98","article-title":"Corrosion behavior of stainless steel weldments in physiological solutions","volume":"5","author":"Farooq","year":"2018","journal-title":"Mater. Res. Express"},{"key":"ref_26","unstructured":"Ely, K.J., Hall, P., and Zhou, Y. (2013). Joining and Assembly of Medical Materials and Devices. In Woodhead Publishing Series in Biomaterials, Woodhead Publishing Limited."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Kolli, S., Javaheri, V., K\u00f6mi, J., and Porter, D. (2019). On the Role of Grain Size and Carbon Content on the Sensitization and Desensitization Behavior of 301 Austenitic Stainless Steel. Metals, 9.","DOI":"10.3390\/met9111193"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"101088","DOI":"10.1016\/j.mtcomm.2020.101088","article-title":"The importance of steel chemistry and thermal history on the sensitization behavior in austenitic stainless steels: Experimental and modeling assessment","volume":"24","author":"Kolli","year":"2020","journal-title":"Mater. Today Commun."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"26","DOI":"10.14773\/cst.2016.15.5.226","article-title":"Intergranular Corrosion Mechanism of Slightly-sensitized and UNSM-treated 316L Stainless Steel","volume":"15","author":"Lee","year":"2016","journal-title":"Corros. Sci. Technol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"A7","DOI":"10.1016\/j.matpr.2022.08.472","article-title":"Improving pitting corrosion resistance of AISI 316L weld overlays via Inconel 82 additions","volume":"62","author":"Kaur","year":"2022","journal-title":"Mater. Today Proc."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.matdes.2012.03.011","article-title":"Studies on pitting corrosion and sensitization in laser rapid manufactured specimens of type 316L stainless steel","volume":"39","author":"Ganesh","year":"2012","journal-title":"Mater. Des."},{"key":"ref_32","first-page":"167","article-title":"The effect of surface treatment AISI 316L welded joints on its corrosion behaviour in chloride solution","volume":"54","author":"Alar","year":"2016","journal-title":"Met. Mater."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.msea.2017.10.002","article-title":"Effect of heat treatment on microstructure, mechanical and corrosion properties of austenitic stainless steel 316L using arc additive manufacturing","volume":"715","author":"Chen","year":"2018","journal-title":"Mater. Sci. Eng. A"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"012104","DOI":"10.1088\/1742-6596\/1436\/1\/012104","article-title":"Corrosion analysis of post-heat treatment and post-weld SS316 with electrokinetic reactivation and cyclic polarization method","volume":"1436","author":"Kartaman","year":"2020","journal-title":"J. Phys. Conf. Ser."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"133143","DOI":"10.1016\/j.matlet.2022.133143","article-title":"Comparing the sensitization behavior and the corrosion resistance of the wrought and selective laser melted 316L stainless steels","volume":"328","author":"Lv","year":"2022","journal-title":"Mater. Lett."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.corsci.2014.12.009","article-title":"Correlation between sensitization and pitting corrosion of AISI 403 martensitic stainless steel","volume":"92","author":"Taji","year":"2015","journal-title":"Corros. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"108520","DOI":"10.1016\/j.corsci.2020.108520","article-title":"Pitting behavior of SLM 316L stainless steel exposed to chloride environments with different aggressiveness: Pitting mechanism induced by gas pores","volume":"167","author":"Duan","year":"2020","journal-title":"Corros. Sci."},{"key":"ref_38","unstructured":"ASTM International (2022, February 20). Standard Practices for Detecting Susceptibility to Intergranular Attack in Austenitic Stainless Steels. Available online: http:\/\/www.tdqs.ru\/static\/doc\/astm_a262_15.pdf."},{"key":"ref_39","unstructured":"(2020). A Designers\u2019 Handbook Series N\u00b0 9001, Nickel Institute."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"\u0160trb\u00e1k, M., Kaj\u00e1nek, D., Knap, V., Florkov\u00e1, Z., Pastorkov\u00e1, J., Hadzima, B., and Goraus, M. (2022). Effect of plasma electrolytic oxidation on the short-term corrosion behaviour of AZ91 magnesium alloy in aggressive chloride environment. Coatings, 12.","DOI":"10.3390\/coatings12050566"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Zatkal\u00edkov\u00e1, V., Uhr\u00ed\u010dik, M., Markovi\u010dov\u00e1, L., and Kucharikov\u00e1, L. (2022). Corrosion Behavior of Sensitized AISI 304 Stainless Steel in Acid Chloride Solution. Materials, 15.","DOI":"10.3390\/ma15238543"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"3615","DOI":"10.1007\/s11665-016-2221-2","article-title":"Intergranular Corrosion Behavior of Low-Nickel and 304 austenitic Stainless Steels","volume":"25","author":"Bandson","year":"2016","journal-title":"J. Mater. Eng. Perform."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"9465","DOI":"10.1016\/S1452-3981(23)16211-0","article-title":"Formation of Cr23C6 during the Sensitization of AISI 304 Stainless Steel and its Effect to Pitting Corrosion","volume":"7","author":"Gakim","year":"2012","journal-title":"Int. J. Electrochem. Sci."},{"key":"ref_44","unstructured":"Elshawesh, F., and Elhoud, A. (2004, January 12\u201316). Role of heat tint on pitting corrosion of 304 austenitic stainless steel in chloride environment. Proceedings of the EUROCORR 2004\u2014Prevision a Long Terme etModelisation de la Corrosion, Nice, France."},{"key":"ref_45","unstructured":"Mahajanam, S., and Heidersbach, K. (2023, June 04). Corrosion Studies of Heat-Tinted Austenitic Stainless Steel. Available online: https:\/\/nace.mydigitalpublication.com\/publication\/?i=704427&article_id=4006538&view=articleBrowser&ver=html5."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1002\/maco.202011597","article-title":"Effects of nitric acid passivation on the corrosion behavior of ZG06Cr13Ni4Mo stainless steel in simulated marine atmosphere","volume":"71","author":"Zhang","year":"2020","journal-title":"Mater. Corros. Werkst. Korros."},{"key":"ref_47","unstructured":"Szklarska\u2013Smialowska, Z. (2005). Pitting and Crevice Corrosion, NACE International. [1st ed.]."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3103\/S1068375518010039","article-title":"Effect of Surface Finish on the Pitting Corrosion Behavior of Sensitized AISI 304 Austenitic Stainless Steel Alloys in 3.5% NaCl Solutions","volume":"54","author":"Ezuber","year":"2018","journal-title":"Surf. Eng. Appl. Electrochem."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.corsci.2017.02.010","article-title":"Pitting corrosion of sensitised type 304 stainless steel under wet\u2013dry cycling condition","volume":"118","author":"Cheng","year":"2017","journal-title":"Corros. Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11837-022-05206-2","article-title":"Pitting Corrosion in 316L Stainless Steel Fabricated by Laser Powder Bed Fusion Additive Manufacturing: A Review and Perspective","volume":"74","author":"Voisin","year":"2022","journal-title":"JOM"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Rokosz, K., Solecki, G., Mori, G., Fluch, R., Kapp, M., and Lahtinen, J. (2020). Effect of Polishing on Electrochemical Behavior and Passive Layer Composition of Different Stainless Steels. Materials, 13.","DOI":"10.3390\/ma13153402"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.procir.2015.07.038","article-title":"Surface finish machining of medical parts using Plasma Electrolytic Polishing","volume":"49","author":"Zeidler","year":"2016","journal-title":"Procedia CIRP"},{"key":"ref_53","unstructured":"Bell, T. (2023, May 03). How to Calculate the Rate of Metal Corrosion. Available online: https:\/\/www.thoughtco.com\/corrosion-rate-calculator-2339697."}],"container-title":["Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1996-1944\/16\/16\/5714\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:38:21Z","timestamp":1760128701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1996-1944\/16\/16\/5714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,21]]},"references-count":53,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["ma16165714"],"URL":"https:\/\/doi.org\/10.3390\/ma16165714","relation":{},"ISSN":["1996-1944"],"issn-type":[{"value":"1996-1944","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,21]]}}}