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The tissues\u2019 viscoelastic properties were characterized by creep tests in tension, applying the load in the direction of the fibers or the transverse direction, and also by dynamic-shear mechanical tests between parallel plates or in tension at frequencies between 0.1 and 35 Hz. All the tests were performed in triplicate at a constant temperature of 37 \u00b0C immersed in distilled water. The tissues\u2019 surface and cross-sectional microstructure were observed by scanning electron microscopy (SEM) to characterize the orientation of the fibers. The matrices of the porcine esophagus present an elastic modulus in the order of 60 MPa when loaded in the longitudinal direction while those of the porcine intestine submucosa and bovine pericardium have an elastic modulus below 5 MPa. Nevertheless, the shear modulus of bovine pericardium nearly triplicates that of the esophageal matrix. The viscoelasticity of decellularized esophageal mucosa is characterized by a fast change in the creep compliance with time. The slope of the creep curve in the double logarithmic plot is twice that of the control samples. These results are consistent with the microstructure observed under electron microscopy regarding the orientation of the fibers that make up the matrices.<\/jats:p>","DOI":"10.3390\/ma17010134","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T02:58:12Z","timestamp":1703645892000},"page":"134","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Viscoelastic Properties of Acellular Matrices of Porcine Esophageal Mucosa and Comparison with Acellular Matrices of Porcine Small Intestine Submucosa and Bovine Pericardium"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1436-1208","authenticated-orcid":false,"given":"Sergio","family":"Estrada Mira","sequence":"first","affiliation":[{"name":"Tissue Engineering and Cells Therapy Group (GITTC), School of Medicine, University of Antioquia, Medellin 050010, Colombia"},{"name":"Cell Therapy and Biobank, Alma Mater Hospital of Antioquia, University of Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-2632","authenticated-orcid":false,"given":"Mar\u00eda Inmaculada","family":"Garc\u00eda-Briega","sequence":"additional","affiliation":[{"name":"Centre for Biomaterials and Tissue Engineering (CBIT), Universitat Polit\u00e8cnica de Val\u00e8ncia, 46022 Valencia, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Bioingenier\u00eda Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9099-0885","authenticated-orcid":false,"given":"Jos\u00e9 Luis","family":"G\u00f3mez Ribelles","sequence":"additional","affiliation":[{"name":"Centre for Biomaterials and Tissue Engineering (CBIT), Universitat Polit\u00e8cnica de Val\u00e8ncia, 46022 Valencia, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Bioingenier\u00eda Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luz M.","family":"Restrepo Munera","sequence":"additional","affiliation":[{"name":"Tissue Engineering and Cells Therapy Group (GITTC), School of Medicine, University of Antioquia, Medellin 050010, Colombia"},{"name":"Cell Therapy and Biobank, Alma Mater Hospital of Antioquia, University of Antioquia, Medellin 050010, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Xing, H., Lee, H., Luo, L., and Kyriakides, T.R. 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