{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T22:18:26Z","timestamp":1790547506427,"version":"4.1.0"},"reference-count":49,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The aim of the present in vitro study was to evaluate specific mechanical and physicochemical properties of three calcium silicate-based sealers, BioRoot\u2122 Flow (BRF), CeraSeal (CRS) and TotalFill\u00ae (TF). Samples were prepared to evaluate different physicochemical and mechanical properties of the tested sealers. These evaluations were accomplished by investigating the pH changes over time, porosity, roughness, flow properties, compressive strength and wettability. The results were statistically evaluated using one-way analysis of variance. All three sealers demonstrated an alkaline pH from 1 h of immersion in water to 168 h. A higher porosity and hydrophily were detected in BRF samples compared to CRS and TF. No significant difference was found between the tested materials in the flow properties. Lower compressive strength values were observed for BRF compared to TF and CRS. Differently shaped structures were detected on the three materials after 7 days of immersion in PBS. The three materials demonstrated a higher solubility than 3% after 24 h of immersion in water (CRS &lt; BRF &lt; TF). The novel premixed calcium silicate sealer (BRF) had comparable physicochemical properties to the existing sealers. The lower compressive strength values could facilitate the removal of these materials during retreatment procedures. Further studies should investigate the biological effects of the novel sealer.<\/jats:p>","DOI":"10.3390\/ma17133374","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T12:21:03Z","timestamp":1720441263000},"page":"3374","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Mechanical and Physicochemical Characteristics of a Novel Premixed Calcium Silicate Sealer"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6768-138X","authenticated-orcid":false,"given":"Naji","family":"Kharouf","sequence":"first","affiliation":[{"name":"Department of Biomaterials and Bioengineering, INSERM UMR_S, Strasbourg University, 67000 Strasbourg, France"},{"name":"Department of Endodontics, Faculty of Dental Medicine, Strasbourg University, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6426-7121","authenticated-orcid":false,"given":"Filippo","family":"Cardinali","sequence":"additional","affiliation":[{"name":"Private Practice, 60123 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raya","family":"Al-Rayesse","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dental Medicine, Damascus University, Damascus 0100, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar","family":"Eid","sequence":"additional","affiliation":[{"name":"Department of Endodontics and Operative Dentistry, Faculty of Dentistry, International University for Science and Technology (IUST), Damascus 011, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad","family":"Moujaes","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Beirut Arab University, Beirut 11-5020, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilda","family":"Nafash","sequence":"additional","affiliation":[{"name":"Private Practice, San Dimas, CA 91773, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6480-1139","authenticated-orcid":false,"given":"Hamdi","family":"Jmal","sequence":"additional","affiliation":[{"name":"ICube Laboratory, UMR 7357 CNRS, Mechanics Department, University of Strasbourg, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4081-9526","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Addiego","sequence":"additional","affiliation":[{"name":"Luxembourg Institute of Science and Technology (LIST), Department Materials Research and Technology (MRT), ZAE Robert Steichen, 5 rue Bommel, L-4940 Luxembourg, Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Haikel","sequence":"additional","affiliation":[{"name":"Department of Biomaterials and Bioengineering, INSERM UMR_S, Strasbourg University, 67000 Strasbourg, France"},{"name":"Department of Endodontics, Faculty of Dental Medicine, Strasbourg University, 67000 Strasbourg, France"},{"name":"P\u00f4le de M\u00e9decine et Chirurgie Bucco-Dentaire, H\u00f4pital Civil, H\u00f4pitaux Universitaire de Strasbourg, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3757","DOI":"10.1007\/s00784-020-03703-9","article-title":"Microscopic and chemical evaluation of the filling quality of five obturation techniques in oval-shaped root canals","volume":"25","author":"Mancino","year":"2021","journal-title":"Clin. 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