{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:12:20Z","timestamp":1790737940355,"version":"4.1.0"},"reference-count":180,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Tooth loss replacement using dental implants is becoming more frequent. Traditional dental implant materials such as commercially pure titanium and titanium aluminum vanadium alloys have well-proven mechanical and biological properties. New titanium alloying metals such as niobium provide improved mechanical properties such as lower elastic modulus while displaying comparable or even better biocompatibility. Hydroxyapatite coatings are a well-documented and widely used method for enhancing dental implants\u2019 surface characteristics and properties and could provide a useful tool for further enhancing titanium\u2013niobium implant properties like osteointegration. Among several coating techniques, physical deposition methods and, in particular, vapour deposition ones are the most used due to their advantages compared to wet deposition techniques for hydroxyapatite coating of metallic surfaces like that of dental implants. Considering the scarcity of data concerning the in vivo evaluation of titanium\u2013niobium biocompatibility and osteointegration and the lack of studies investigating coating these new proposed alloys with hydroxyapatite, this review aims to further knowledge on hydroxyapatite-coated titanium niobium alloys.<\/jats:p>","DOI":"10.3390\/ma17246206","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T06:50:44Z","timestamp":1734591044000},"page":"6206","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Exploring the Broad Spectrum of Titanium\u2013Niobium Implants and Hydroxyapatite Coatings\u2014A Review"],"prefix":"10.3390","volume":"17","author":[{"given":"Radu","family":"Radulescu","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 8 Eroilor Sanitari Blvd, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Mele\u0219canu Imre","sequence":"additional","affiliation":[{"name":"Department of Complete Denture, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 17-23 Calea Plevnei, 010221 Bucharest, Romania"},{"name":"The Interdisciplinary Center for Dental Research and Development, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 19-21 Jean Louis Calderon Street, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4345-282X","authenticated-orcid":false,"given":"Alexandra","family":"Ripszky","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 8 Eroilor Sanitari Blvd, 050474 Bucharest, Romania"},{"name":"The Interdisciplinary Center for Dental Research and Development, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 19-21 Jean Louis Calderon Street, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5255-6004","authenticated-orcid":false,"given":"Florentina","family":"Rus","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 8 Eroilor Sanitari Blvd, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Popa","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 8 Eroilor Sanitari Blvd, 050474 Bucharest, Romania"},{"name":"The Interdisciplinary Center for Dental Research and Development, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 19-21 Jean Louis Calderon Street, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai","family":"Moisa","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 8 Eroilor Sanitari Blvd, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Funieru","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, Faculty of Dental Medicine, University of Medicine and Pharmacy Carol Davila, 4 Eforiei, 050037 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razvan","family":"Ene","sequence":"additional","affiliation":[{"name":"Orthopedics and Traumatology Department, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silviu","family":"Pituru","sequence":"additional","affiliation":[{"name":"The Interdisciplinary Center for Dental Research and Development, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 19-21 Jean Louis Calderon Street, 020021 Bucharest, Romania"},{"name":"Department of Professional Organization and Medical Legislation-Malpractice, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Glick, M., Urquhart, O., Bhosale, A.S., Carrasco-Labra, A., and Edelson, J.T. 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