{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:39:12Z","timestamp":1788820752452,"version":"build-2803163510"},"reference-count":78,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:00:00Z","timestamp":1736899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Infections continue to pose significant challenges in dentistry, necessitating the development of innovative solutions that can effectively address these issues. This study focuses on creating coatings made from polymethyl methacrylate (PMMA) enriched with zinc oxide\u2013silver composite nanoparticles, layered to Ti6Al4V\u2013titanium alloy substrates. The application of these materials aims to create a solution for the abutments utilized in complete dental implant systems, representing the area most susceptible to bacterial infections. The nanoparticles were synthesized using a hydrothermal method, optimized through specific temperature and pressure parameters to achieve effective morphologies and sizes that enhance antibacterial efficacy. The layers were applied to the titanium substrate using the spin coating technique, chosen for its advantages and compatibility with the materials involved. Comprehensive analyses were conducted on the antimicrobial powders, including X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. Furthermore, the PMMA-based coatings incorporating antimicrobial nanoparticles were evaluated to ensure uniformity and homogeneity across the titanium alloy surface by IR mapping and SBF immersion\u2013SEM analysis. The antimicrobial activity of the samples was demonstrated with impressive results against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans, as assessed through biofilm modulation studies. The biocompatibility of the samples was validated through in vitro cell-based assays, which demonstrated excellent compatibility between PMMA-based coatings and human preosteoblasts, confirming their potential suitability for future use in dental implants.<\/jats:p>","DOI":"10.3390\/ma18020382","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T04:55:19Z","timestamp":1737003319000},"page":"382","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Antibacterial Properties of PMMA\/ZnO(NanoAg) Coatings for Dental Implant Abutments"],"prefix":"10.3390","volume":"18","author":[{"given":"Ana Maria Gianina","family":"Rehner (Costache)","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana-Ionela","family":"Tudorache","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. Polizu Str. 1\u20137, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra C\u0103t\u0103lina","family":"B\u00eerc\u0103","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. Polizu Str. 1\u20137, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4133-7377","authenticated-orcid":false,"given":"Adrian Ionu\u021b","family":"Nicoar\u0103","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. Polizu Str. 1\u20137, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8968-504X","authenticated-orcid":false,"given":"Adelina-Gabriela","family":"Niculescu","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. Polizu Str. 1\u20137, 060042 Bucharest, Romania"},{"name":"Research Institute of the University of Bucharest\u2014ICUB, University of Bucharest, 050657 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Maria","family":"Holban","sequence":"additional","affiliation":[{"name":"Faculty of Biology, University of Bucharest, Aleea Portocalelor 1\u20133, Sector 5, 030018 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9439-9432","authenticated-orcid":false,"given":"Ariana","family":"Hudi\u021b\u0103","sequence":"additional","affiliation":[{"name":"Research Institute of the University of Bucharest\u2014ICUB, University of Bucharest, 050657 Bucharest, Romania"},{"name":"Faculty of Biology, University of Bucharest, Aleea Portocalelor 1\u20133, Sector 5, 030018 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florentina Cornelia","family":"B\u00eeclesanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4810-2992","authenticated-orcid":false,"given":"Paul C\u0103t\u0103lin","family":"Balaure","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. Polizu Str. 1\u20137, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Pangic\u0103","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3036-094X","authenticated-orcid":false,"given":"Alexandru Mihai","family":"Grumezescu","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, Gh. 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