{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T23:23:35Z","timestamp":1780701815661,"version":"3.54.1"},"reference-count":43,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japanese Society of Orthodontics"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>This study aimed to investigate the release of metallic ions from cobalt\u2013chromium (Co-Cr) alloys fabricated by additive manufacturing (AM) for comparison with dental casting. Co-Cr alloys were fabricated via AM using selective laser melting (SLM) and electron beam melting (EBM) in powder-bed fusion. Polished and mechanically ground specimens were prepared. Each specimen was analyzed using an electron probe microanalyzer (EPMA). Each specimen was immersed in an acidic saline solution for 7 days in accordance with ISO 10271: 2020. The EPMA indicated the segregation of some elements in the as-prepared SLM and EBM specimens, whereas the polished and ground specimens exhibited a homogenous elemental distribution. The total amount of ion release from the SLM and EBM specimens was confirmed to be less than 7 \u03bcg\/cm2, which was less than 42 \u03bcg\/cm2 for the cast specimen. The polished and ground specimens exhibited an even lower ion release than the as-prepared specimens. The amount of ions released from the Co-Cr alloy was less than the 200 \u03bcg\/cm\u00b2 requirement of ISO 22674: 2022. Co-Cr alloys fabricated by SLM and EBM could provide superior corrosion resistance to cast specimens. AM could be a valuable method for fabricating appliances and denture frameworks in dentistry.<\/jats:p>","DOI":"10.3390\/ma18020432","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T11:24:56Z","timestamp":1737113096000},"page":"432","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Metallic Ion Release Behaviors from Cobalt\u2013Chromium Alloys Fabricated by Additive Manufacturing with Mechanical Grinding in an Acidic Saline Solution"],"prefix":"10.3390","volume":"18","author":[{"given":"Naoto","family":"Sakurai","sequence":"first","affiliation":[{"name":"Division of Orthodontic, Department of Developmental Oral Health Science, School of Dentistry, Iwate Medical University, Iwate 020-8505, Japan"},{"name":"Department of Biomedical Engineering, Iwate Medical University, Iwate 028-3694, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4937-7111","authenticated-orcid":false,"given":"Tomofumi","family":"Sawada","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Iwate Medical University, Iwate 028-3694, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8999-0132","authenticated-orcid":false,"given":"Yukinori","family":"Kuwajima","sequence":"additional","affiliation":[{"name":"Division of Orthodontic, Department of Developmental Oral Health Science, School of Dentistry, Iwate Medical University, Iwate 020-8505, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1675-4731","authenticated-orcid":false,"given":"Kenta","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoyuki","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Materials Processing, Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Department of Dental Materials Science, Tokyo Dental College, Tokyo 101-0061, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Chiba","sequence":"additional","affiliation":[{"name":"New Industry Creation Hatchery Center, Tohoku University, Sendai 980-8577, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuro","family":"Satoh","sequence":"additional","affiliation":[{"name":"Division of Orthodontic, Department of Developmental Oral Health Science, School of Dentistry, Iwate Medical University, Iwate 020-8505, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4231-3262","authenticated-orcid":false,"given":"Shinji","family":"Takemoto","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Iwate Medical University, Iwate 028-3694, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"key":"ref_1","unstructured":"Ratner, B.D., Hoffman, A.S., Schoen, F.J., and Lemons, J.E. 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