{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:59:06Z","timestamp":1790834346363,"version":"4.1.0"},"reference-count":36,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The selection of cross-linking techniques is essential for the development of the alginate matrix. In this study, we investigated porous sodium alginate matrices (ALG1@in, ALG3@in, ALG5@in) synthesized by internal gelation and further functionalized with polyphosphate (PP) at concentrations of 5% and 15% (ALG3@inPP5, ALG3@inPP15). Extensive characterizations were conducted, employing scanning electron microscopy coupled with energy-dispersive spectroscopy (SEM-EDS) for morphological and compositional analysis, Fourier transform infrared spectroscopy (FTIR-ATR) for structural elucidation, thermogravimetric analysis (TGA-DTG) for thermal stability, and porosimetry (ASAP) for surface area and pore size evaluation. Surface charge density (pHZPC) was determined, and Ca2\u207a release kinetics were monitored in demineralized water over 7 days and Dulbecco\u2019s phosphate-buffered saline (DPBS) over 14 days. The increase in sodium alginate concentration increases the BET surface area and pore volume, which improves adsorption and transport properties. The thermal stability of the tested matrices at 37 \u00b0C confirms their suitability for biomedical applications. The ALG3@in sample showed the best parameters, combining high BET surface area (11.02 m2\/g), significant pore volume (0.08 cm3\/g) and thermal stability up to 257 \u00b0C, making it a suitable candidate for applications in biology, tissue engineering and processes requiring sterilization and high temperatures. These findings underscore the potential of polyphosphate modifications to improve alginate matrices, opening avenues for future applications in areas like cell culture scaffolds or environmental chemistry solutions.<\/jats:p>","DOI":"10.3390\/ma18051114","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T03:22:44Z","timestamp":1740972164000},"page":"1114","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comprehensive Physicochemical Analysis of Polyphosphate-Modified Alginate Matrices: Synthesis, Structural Analysis, and Calcium Ion Release Dynamics"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9202-0081","authenticated-orcid":false,"given":"Alicja","family":"Wawszczak","sequence":"first","affiliation":[{"name":"Department of Inorganic Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sk\u0142odowska University, M. Curie Sk\u0142odowska Sq. 2, 20-031 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Czemierska","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Maria Curie-Sk\u0142odowska University, Akademicka 19, 20-031 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8222-4379","authenticated-orcid":false,"given":"Anna","family":"Jarosz-Wilko\u0142azka","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Maria Curie-Sk\u0142odowska University, Akademicka 19, 20-031 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1788-5648","authenticated-orcid":false,"given":"Dorota","family":"Ko\u0142ody\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Inorganic Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sk\u0142odowska University, M. Curie Sk\u0142odowska Sq. 2, 20-031 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"128265","DOI":"10.1016\/j.seppur.2024.128265","article-title":"Recent Advances in Alginate-Based Hydrogels for the Adsorption\u2013Desorption of Heavy Metal Ions from Water: A Review","volume":"353","author":"Chen","year":"2025","journal-title":"Sep. Purif. Technol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"113078","DOI":"10.1016\/j.eurpolymj.2024.113078","article-title":"A Review on Sources, Modification Techniques, Properties and Potential Applications of Alginate-Based Modified Polymers","volume":"213","author":"Kumar","year":"2024","journal-title":"Eur. Polym. J."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Wang, H., Yang, L., and Yang, Y. (2025). 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