{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T19:47:44Z","timestamp":1788810464917,"version":"build-2803163510"},"reference-count":68,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>This study involved the fabrication of poly (vinyl alcohol) (PVA) nanocomposite films using the solution-casting process, which incorporated strontium-coated silver oxide (Sr-Ag2O) nanoparticles generated by a plant-extract assisted method. Various characterization techniques, such as XRD, SEM, TEM, UV, and FTIR, showed the formation and uniform distribution of Sr-Ag2O nanoparticles in the PVA film, which are biocompatible nanocomposite films. The presence of hydroxyl groups leads to appreciable mixing and interaction between the Sr-Ag2O nanoparticles and the PVA polymer. Mechanical and thermal results suggest enhanced tensile strength and increased thermal stability. In addition, the sample of PVA\/Sr-Ag2O (1.94\/0.06 wt. ratio) nanocomposite film showed decreased hydrophilicity, lower hemolysis, non-toxicity, and appreciable cell migration activity, with nearly 19.95% cell migration compared to the standard drug, and the presence of Sr-Ag2O nanoparticles favored the adhesion and spreading of cells, which triggered the reduction in the gaps. These research findings suggest that PVA\/Sr-Ag2O nanocomposite films with good mechanical, antimicrobial, non-toxic, and biocompatible properties could be applied in biological wound-healing applications.<\/jats:p>","DOI":"10.3390\/ma18153568","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:55:37Z","timestamp":1753872937000},"page":"3568","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Strontium-Decorated Ag2O Nanoparticles Obtained via Green Synthesis\/Polyvinyl Alcohol Films for Wound Dressing Applications"],"prefix":"10.3390","volume":"18","author":[{"given":"Vanita","family":"Ghatti","sequence":"first","affiliation":[{"name":"Department of Chemistry, Faculty of Engineering and Technology, Jain University, Jakkasandra 562112, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1798-5278","authenticated-orcid":false,"given":"Sharanappa","family":"Chapi","sequence":"additional","affiliation":[{"name":"Department of Physics, B.M.S. College of Engineering, Bengaluru 560019, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Kumar Kumarswamy","sequence":"additional","affiliation":[{"name":"Department of Sciences, Alliance School of Sciences, Alliance University, Central Campus, Anekal, Bengaluru 562106, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7067-5394","authenticated-orcid":false,"given":"Nagaraj","family":"Nandihalli","sequence":"additional","affiliation":[{"name":"Critical Materials Innovation Hub, Ames National Laboratory, U.S. Department of Energy, Iowa State University, Ames, IA 50011, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3004-2044","authenticated-orcid":false,"given":"Deepak R.","family":"Kasai","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Engineering and Technology, Jain University, Jakkasandra 562112, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"981","DOI":"10.3390\/pharmaceutics13070981","article-title":"The insights of microbes\u2019 roles in wound healing: A comprehensive review","volume":"13","author":"Thambirajoo","year":"2021","journal-title":"Pharmaceutics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/0022034509359125","article-title":"Factors affecting wound healing","volume":"89","author":"Guo","year":"2010","journal-title":"J. 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