{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:56:17Z","timestamp":1781844977907,"version":"3.54.5"},"reference-count":34,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Project of CNPC Chuanqing Drilling Engineering Company Limited","award":["CQ2025B-6-5-3"],"award-info":[{"award-number":["CQ2025B-6-5-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>An anti-contamination agent (Zn\/Al\u2013ATMP\u2013LDH) was synthesized by intercalation and used to correct the abnormal thickening and related operational risks caused by contact contamination between drilling fluids and cement slurries during high-temperature\/high-pressure cementing. The experimental results show that the agent is chemically stable and exhibits good compatibility with conventional spacer fluid additives. When compared with the direct addition of amino tris(methylenephosphonic acid) (ATMP), confining ATMP within a layered double hydroxide (LDH) markedly mitigates the retarding effect. At a dosage exceeding 0.3 wt%, the compressive strength of cement stone increased from 0 to 32.84 MPa following curing at 90 \u00b0C for 1 day and continued to develop steadily after 7 days. Following conditioning at 187 \u00b0C and 145 MPa for 120 min, the spacer system formulated using the proposed agent as the core component served to enhance the rheology of the mixed slurry via synergistic adsorption\u2013regulation\u2013dispersion stabilization-controlled release. The mixed slurry maintained stable rheological properties before and after aging with no uncontrolled thickening. When mixing the cement slurry and drilling fluid at a 7:3 volume ratio, the slurry consistency exceeded 60 Bc within 1 h, failing to meet operational requirements. In contrast, the mixed slurry containing the anti-contamination spacer (cement slurry\u2013drilling fluid\u2013spacer = 7:2:1) exhibited a thickening time greater than 300 min and was successfully applied in field-cementing operations in a well in the Gaomo area.<\/jats:p>","DOI":"10.3390\/ma19122595","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:58:38Z","timestamp":1781661518000},"page":"2595","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preparation and Application of a Novel Anti-Contamination Agent for Use in Drilling Fluids"],"prefix":"10.3390","volume":"19","author":[{"given":"Song","family":"Zhang","sequence":"first","affiliation":[{"name":"Chuanqing Drilling Engineering Co., Ltd., Drilling Fluid Technology Services Company, Chengdu 610051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Guan","sequence":"additional","affiliation":[{"name":"School of New Energy and Materials, Southwest Petroleum University, Chengdu 610500, China"},{"name":"Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Deng","sequence":"additional","affiliation":[{"name":"School of New Energy and Materials, Southwest Petroleum University, Chengdu 610500, China"},{"name":"Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7975-7254","authenticated-orcid":false,"given":"Xiaowei","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of New Energy and Materials, Southwest Petroleum University, Chengdu 610500, China"},{"name":"Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2118\/1111-0065-JPT","article-title":"Improving compatibility of drilling fluid, completion fluid, and other well-treatment fluids for deepwater wells","volume":"63","author":"Dennis","year":"2011","journal-title":"J. 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