{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:04:48Z","timestamp":1784174688407,"version":"3.55.0"},"reference-count":45,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"framework of state assignments","award":["1023022600041-9-3.4.4"],"award-info":[{"award-number":["1023022600041-9-3.4.4"]}]},{"name":"gas chromatography data analysis","award":["075-00224-26-00"],"award-info":[{"award-number":["075-00224-26-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The purpose of this study is to investigate the physical, chemical, and structural characteristics of 13 polypropylene mesh endoprostheses explanted due to hernia recurrences across an in vivo timeline ranging from 1 to 14 years, as well as the morphology of the surrounding tissues, to assess the possible influence of polymer degradation on explantation timing. Physical and mechanical testing, gas chromatography\u2013mass spectrometry, differential scanning calorimetry, infrared spectroscopy, and histological assessment of tissue response to the implanted endoprostheses were employed. The tensile strength and elongation measurements of the explanted meshes remained within functionally acceptable clinical ranges, showing no statistically significant decline compared to baseline parameters. Polypropylene monofilaments of mesh endoprostheses were subjected to surface changes in the form of transverse cracks during exposure to patient tissues; however, the depth of these cracks was self-limiting (confined to 3\u20137% of the filament diameter) and did not affect the bulk strength properties of the endoprostheses. Histological examination demonstrated a chronic foreign body response that transitioned from early focal necrosis to a stable tissue capsule. While these data suggest that superficial micro-cracking did not markedly compromise bulk mechanical performance over the 14-year span, localized physical or biological tissue\u2013implant interactions could still contribute to structural instability, meaning polymer degradation cannot be definitively ruled out as a contributing factor to recurrence in all clinical cases.<\/jats:p>","DOI":"10.3390\/ma19143048","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:34:23Z","timestamp":1784172863000},"page":"3048","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Physicochemical, Mechanical, and Histological Assessment of Explanted Polypropylene Meshes from Recurrent Abdominal Wall Hernia Repairs"],"prefix":"10.3390","volume":"19","author":[{"given":"Olga A.","family":"Legonkova","sequence":"first","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatyana I.","family":"Vinokurova","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8725-2320","authenticated-orcid":false,"given":"Viktoria V.","family":"Stafford","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"},{"name":"All-Russian Research Institute of Experimental Veterinary Medicine Named After K.I. Scriabin and Y.R. Kovalenko (Federal Scientific Center), Russian Academy of Sciences, Ryazansky Prospekt 24\/1, Moscow 109428, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5791-4917","authenticated-orcid":false,"given":"Dmitriy I.","family":"Kopitsyn","sequence":"additional","affiliation":[{"name":"Department of Chemical Technology and Ecology, Gubkin Russian State University of Oil and Gas (National Research University), Leninsky Prospekt 65, Moscow 119991, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Badri S.","family":"Gogia","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4215-7084","authenticated-orcid":false,"given":"Galina A.","family":"Davydova","sequence":"additional","affiliation":[{"name":"Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya St. 3, Pushchino, Serpukhov District, Pushchino 142290, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egor V.","family":"Kasatkin","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9035-6543","authenticated-orcid":false,"given":"Mariya I.","family":"Styazhkina","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rifat R.","family":"Alyautdinov","sequence":"additional","affiliation":[{"name":"A.V. Vishnevsky National Medical Research Center of Surgery, Ministry of Health of the Russian Federation, Bolshaya Serpukhovskaya St. 27, Moscow 117997, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir A.","family":"Vinokurov","sequence":"additional","affiliation":[{"name":"Department of Chemical Technology and Ecology, Gubkin Russian State University of Oil and Gas (National Research University), Leninsky Prospekt 65, Moscow 119991, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0743-2629","authenticated-orcid":false,"given":"Victoria Yu.","family":"Grigorieva","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy, Department of Analytical, Physical and Colloid Chemistry, Sechenov First Moscow State Medical University, Trubetskaya St. 8, Build. 2, Moscow 119048, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2535-5698","authenticated-orcid":false,"given":"Veronica","family":"Manescu (Paltanea)","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania"},{"name":"Faculty of Electrical Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0112-3494","authenticated-orcid":false,"given":"Iulian Vasile","family":"Antoniac","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania"},{"name":"Academy of Romanian Scientists, 54 Splaiul Independentei, RO-050094 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7953-1853","authenticated-orcid":false,"given":"Julietta V.","family":"Rau","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy, Department of Analytical, Physical and Colloid Chemistry, Sechenov First Moscow State Medical University, Trubetskaya St. 8, Build. 2, Moscow 119048, Russia"},{"name":"Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"ref_1","first-page":"582","article-title":"Biomaterials and hernia surgery. 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