{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T05:12:09Z","timestamp":1788671529039,"version":"build-2803163510"},"reference-count":48,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004382","name":"Polish Academy of Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004382","id-type":"DOI","asserted-by":"crossref"}]},{"id":[{"id":"https:\/\/ror.org\/01dr6c206","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005995","name":"Bulgarian Academy of Sciences","doi-asserted-by":"publisher","award":["IC-PL\/08\/2026-2027"],"award-info":[{"award-number":["IC-PL\/08\/2026-2027"]}],"id":[{"id":"10.13039\/501100005995","id-type":"DOI","asserted-by":"publisher"}]},{"award":["IC-PL\/08\/2026-2027"],"award-info":[{"award-number":["IC-PL\/08\/2026-2027"]}],"id":[{"id":"https:\/\/ror.org\/01x8hew03","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The development of straightforward and efficient strategies for the preparation of polymer-functionalized mesoporous silica remains an important challenge in the design of advanced hybrid materials. Herein, we report a novel and simplified approach to the covalent functionalization of mesoporous silica particles (MSP) with poly(2-ethyl-2-oxazoline) (PEtOx), based on the direct termination of living cationic polymer chains by amino groups immobilized on the silica surface. In contrast to conventional grafting-to methods, the proposed strategy eliminates the need for polymer end-group functionalization while avoiding the synthetic complexity associated with surface-initiated polymerization. Well-defined PEtOx chains with number-average molar masses of 5000 and 7500 g mol\u22121 were synthesized by cationic ring-opening polymerization (CROP) and subsequently grafted onto amino-functionalized MSP. Successful covalent immobilization of the polymer was confirmed by Fourier-transform infrared spectroscopy (FT-IR), elemental analysis, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), transmission electron microscopy (TEM), contact angle measurements, and nitrogen adsorption\u2013desorption studies. The modification preserved the ordered mesoporous architecture while increasing particle hydrophilicity and decreasing the specific surface area and pore volume due to polymer incorporation. Shorter polymer chains exhibited higher grafting efficiency than higher-molar-mass analog, indicating that steric hindrance is an important factor influencing the grafting process. The presented methodology provides a versatile and experimentally accessible platform for the preparation of well-defined poly(2-oxazoline)-functionalized mesoporous silica with tunable physicochemical properties. Owing to the combination of a porous inorganic framework and a polymer shell, the obtained hybrid materials represent promising candidates for drug delivery, adsorption technologies, and other advanced biomedical and environmental applications.<\/jats:p>","DOI":"10.3390\/ma19173775","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:07:32Z","timestamp":1788538052000},"page":"3775","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Direct Immobilization of Living Poly(2-ethyl-2-oxazoline) Chains onto Mesoporous Silica: A Simplified Grafting-To Strategy for Hybrid Organic\u2013Inorganic Materials"],"prefix":"10.3390","volume":"19","author":[{"given":"Marcelina","family":"Bochenek","sequence":"first","affiliation":[{"name":"Centre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Margarita","family":"Popova","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Natalia","family":"Oleszko-Torbus","sequence":"additional","affiliation":[{"name":"Centre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5400-4379","authenticated-orcid":false,"given":"Agnieszka","family":"Kowalczuk","sequence":"additional","affiliation":[{"name":"Centre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9726-0137","authenticated-orcid":false,"given":"Alicja","family":"Utrata-Weso\u0142ek","sequence":"additional","affiliation":[{"name":"Centre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2714-7980","authenticated-orcid":false,"given":"Violeta","family":"Mitova","sequence":"additional","affiliation":[{"name":"Institute of Polymers, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8445-8953","authenticated-orcid":false,"given":"Neli","family":"Koseva","sequence":"additional","affiliation":[{"name":"Institute of Polymers, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2037-6227","authenticated-orcid":false,"given":"El\u017cbieta","family":"Grz\u0105dka","sequence":"additional","affiliation":[{"name":"Physical Chemistry Department, Faculty of Chemistry, Institute of Chemical Sciences, Maria Curie-Sk\u0142odowska University, M. 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