{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T17:17:52Z","timestamp":1781111872938,"version":"3.54.1"},"reference-count":174,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>Biological creatures with unique surface wettability have long served as a source of inspiration for scientists and engineers. More specifically, materials exhibiting extreme wetting properties, such as superhydrophilic and superhydrophobic surfaces, have attracted considerable attention because of their potential use in various applications, such as self-cleaning fabrics, anti-fog windows, anti-corrosive coatings, drag-reduction systems, and efficient water transportation. In particular, the engineering of surface wettability by manipulating chemical properties and structure opens emerging biomedical applications ranging from high-throughput cell culture platforms to biomedical devices. This review describes design and fabrication methods for artificial extreme wetting surfaces. Next, we introduce some of the newer and emerging biomedical applications using extreme wetting surfaces. Current challenges and future prospects of the surfaces for potential biomedical applications are also addressed.<\/jats:p>","DOI":"10.3390\/ma9020116","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T11:29:39Z","timestamp":1455881379000},"page":"116","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":122,"title":["Bio-Inspired Extreme Wetting Surfaces for Biomedical Applications"],"prefix":"10.3390","volume":"9","author":[{"given":"Sera","family":"Shin","sequence":"first","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungmok","family":"Seo","sequence":"additional","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heetak","family":"Han","sequence":"additional","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subin","family":"Kang","sequence":"additional","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyunchul","family":"Kim","sequence":"additional","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8269-0257","authenticated-orcid":false,"given":"Taeyoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Nanobio Device Laboratory, School of Electrical and Electronic Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-Gu, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.nantod.2011.02.002","article-title":"Bio-inspired design of multiscale structures for function integration","volume":"6","author":"Liu","year":"2011","journal-title":"Nano Today"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"11217","DOI":"10.1039\/c2sm26517f","article-title":"Recent developments in superhydrophobic surfaces with unique structural and functional properties","volume":"8","author":"Zhang","year":"2012","journal-title":"Soft Matter"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1039\/C1SM07003G","article-title":"Extreme wettability and tunable adhesion: Biomimicking beyond nature?","volume":"8","author":"Liu","year":"2012","journal-title":"Soft Matter"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jcis.2013.12.019","article-title":"Anti-fouling properties of microstructured surfaces bio-inspired by rice leaves and butterfly wings","volume":"419","author":"Bixler","year":"2014","journal-title":"J. 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