{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:34:30Z","timestamp":1789914870709,"version":"4.0.1"},"reference-count":19,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T00:00:00Z","timestamp":1470700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Materials"],"abstract":"<jats:p>The recent scandal of poly implant prostheses (PIP), which were found in some cases to be made of non-medical grade silicone (as reported by the European Scientific Committee on Emerging and Newly Identified Health Risks), had a great social impact. Thousands of patients asked for implant removal with significant costs for public health care systems. We analysed, by a multidisciplinary approach, sixteen different breast implants after explantation by using several analytical and structural techniques, such as Fourier Transform infrared spectroscopy (FT-IR), mass spectrometry equipped by ion coupled plasma (ICP-MS), gas-chromatography (GC-MS), and tensile testing. Traces of organic (fatty acid) and inorganic (Fe, Cr, Pt, Na, and other metals) substances were found in all samples, and, even if these values are under danger threshold levels, our study results highlight the possibility of bioaccumulation and tissue contamination, implying the need for continuous medical surveillance and monitoring of material aging.<\/jats:p>","DOI":"10.3390\/ma9080678","type":"journal-article","created":{"date-parts":[[2016,8,9]],"date-time":"2016-08-09T09:14:10Z","timestamp":1470734050000},"page":"678","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Chemical and Structural Characterization of Several Mid-Term Explanted Breast Prostheses"],"prefix":"10.3390","volume":"9","author":[{"given":"Angela","family":"Amoresano","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Complesso Universitario di Monte Sant\u2019Angelo, Via Cinthia, Napoli 80100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9442-4175","authenticated-orcid":false,"given":"Luca","family":"De Stefano","sequence":"additional","affiliation":[{"name":"CNR-IMM, Istituto per la Microelettronica e Microsistemi, Unit\u00e0 di Napoli, Via P. Castellino 111, Napoli 80131, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Rea","sequence":"additional","affiliation":[{"name":"CNR-IMM, Istituto per la Microelettronica e Microsistemi, Unit\u00e0 di Napoli, Via P. Castellino 111, Napoli 80131, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Pane","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Complesso Universitario di Monte Sant\u2019Angelo, Via Cinthia, Napoli 80100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Birolo","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Complesso Universitario di Monte Sant\u2019Angelo, Via Cinthia, Napoli 80100, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Schonauer","sequence":"additional","affiliation":[{"name":"Dipartimento di Patologia Sistematica, University of Napoli \u201cFederico II\u201d, Via S. Pansini 5, Napoli 80131, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,8,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"480e","DOI":"10.1097\/PRS.0b013e3182818a00","article-title":"Rupture of Poly Implant Prothese SiliconeBreast Implants: An Implant Retrieval Study","volume":"4","author":"Swarts","year":"2013","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1097\/PRS.0b013e3182827605","article-title":"The Impact of Poly Implant Prothese Fraud on Breast Cancer Patients: A Report by the Institut Curie","volume":"4","author":"Reyal","year":"2013","journal-title":"Plast. Reconstr. 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Chem."}],"container-title":["Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1996-1944\/9\/8\/678\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:28:04Z","timestamp":1760210884000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1996-1944\/9\/8\/678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,9]]},"references-count":19,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,8]]}},"alternative-id":["ma9080678"],"URL":"https:\/\/doi.org\/10.3390\/ma9080678","relation":{},"ISSN":["1996-1944"],"issn-type":[{"value":"1996-1944","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,9]]}}}