{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:58:21Z","timestamp":1790049501746,"version":"4.0.1"},"reference-count":18,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>A dichloromethane extract of the soft coral Rhytisma fulvum fulvum collected in Madagascar afforded a novel compound possessing an unprecedented pentacyclic skeleton, bisdioxycalamenene (1), as well as seven known sesquiterpenes. The structures of the compounds were elucidated using 1D and 2D NMR techniques, as well as high-resolution mass spectrometry. The absolute configuration of 1 was determined using X-ray diffraction analysis and anomalous dispersion effects. The structure elucidation and a possible biogenesis of the compound are discussed.<\/jats:p>","DOI":"10.3390\/md14020041","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T11:29:39Z","timestamp":1455881379000},"page":"41","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum"],"prefix":"10.3390","volume":"14","author":[{"given":"Yuval","family":"Trifman","sequence":"first","affiliation":[{"name":"School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Aknin","sequence":"additional","affiliation":[{"name":"Laboratory of Chemistry of Natural Substances and Food Sciences, Faculty of Science and Technology, University of Reunion Island, 15 Avenue Rene\u0301 Cassin, CS 92003, 97744 Saint-Denis Cedex 9, La Reunion, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Gauvin-Bialecki","sequence":"additional","affiliation":[{"name":"Laboratory of Chemistry of Natural Substances and Food Sciences, Faculty of Science and Technology, University of Reunion Island, 15 Avenue Rene\u0301 Cassin, CS 92003, 97744 Saint-Denis Cedex 9, La Reunion, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehuda","family":"Benayahu","sequence":"additional","affiliation":[{"name":"Department of Zoology, George S. 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