{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T02:09:59Z","timestamp":1782698999716,"version":"3.54.5"},"reference-count":59,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2018,5,12]],"date-time":"2018-05-12T00:00:00Z","timestamp":1526083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>This review focuses on marine compounds with anti-prostate cancer properties. Marine species are unique and have great potential for the discovery of anticancer drugs. Marine sources are taxonomically diverse and include bacteria, cyanobacteria, fungi, algae, and mangroves. Marine-derived compounds, including nucleotides, amides, quinones, polyethers, and peptides are biologically active compounds isolated from marine organisms such as sponges, ascidians, gorgonians, soft corals, and bryozoans, including those mentioned above. Several compound classes such as macrolides and alkaloids include drugs with anti-cancer mechanisms, such as antioxidants, anti-angiogenics, antiproliferatives, and apoptosis-inducing drugs. Despite the diversity of marine species, most marine-derived bioactive compounds have not yet been evaluated. Our objective is to explore marine compounds to identify new treatment strategies for prostate cancer. This review discusses chemically and pharmacologically diverse marine natural compounds and their sources in the context of prostate cancer drug treatment.<\/jats:p>","DOI":"10.3390\/md16050160","type":"journal-article","created":{"date-parts":[[2018,5,14]],"date-time":"2018-05-14T02:57:20Z","timestamp":1526266640000},"page":"160","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Investigation of the Anti-Prostate Cancer Properties of Marine-Derived Compounds"],"prefix":"10.3390","volume":"16","author":[{"given":"Meiqi","family":"Fan","sequence":"first","affiliation":[{"name":"Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Nath","sequence":"additional","affiliation":[{"name":"Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujiao","family":"Tang","sequence":"additional","affiliation":[{"name":"Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea"},{"name":"School of Bio-Science and Food Engineering, Changchun University of Science and Technology, Changchun 130-600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trishna","family":"Debnath","sequence":"additional","affiliation":[{"name":"Department of Food Science and Biotechnology, Dongguk University, Goyang 10326, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Ju","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Physical Education, College of Education, Daegu Catholic University, Gyeongsan 38430, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4832-6427","authenticated-orcid":false,"given":"Eun-Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,5,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1055\/s-0034-1383001","article-title":"Exploring marine resources for bioactive compounds","volume":"80","author":"Kiuru","year":"2014","journal-title":"Planta Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1128\/MMBR.05024-11","article-title":"Biochemistry and evolution of anaerobic energy metabolism in eukaryotes","volume":"76","author":"Mentel","year":"2012","journal-title":"Microbiol. 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