{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:02:45Z","timestamp":1760709765249,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:00:00Z","timestamp":1542758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["17-14-01065"],"award-info":[{"award-number":["17-14-01065"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>Four new oxysterols 1\u20134 along with previously known oxygenated sterols 5\u201314 were isolated from the sponge Inflatella sp., collected from the Sea of Okhotsk. Structures of 1\u20134 were elucidated by the detailed NMR spectroscopic and mass-spectrometric analyses as well as by comparison of the corresponding experimental data with those reported in literature. The influence of compounds 1\u201314 on the viability of neuronal Neuro2a cells treated by 6-hydroxydopamine and reactive oxygen species (ROS) formation in these cells was investigated.<\/jats:p>","DOI":"10.3390\/md16110458","type":"journal-article","created":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T09:18:25Z","timestamp":1542878305000},"page":"458","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Oxysterols from a Marine Sponge Inflatella sp. and Their Action in 6-Hydroxydopamine-Induced Cell Model of Parkinson\u2019s Disease"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4405-8496","authenticated-orcid":false,"given":"Sophia A.","family":"Kolesnikova","sequence":"first","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina G.","family":"Lyakhova","sequence":"additional","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anatoly I.","family":"Kalinovsky","sequence":"additional","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman S.","family":"Popov","sequence":"additional","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina A.","family":"Yurchenko","sequence":"additional","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentin A.","family":"Stonik","sequence":"additional","affiliation":[{"name":"G.B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC), Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia"},{"name":"School of Natural Science, Far Eastern Federal University, Sukhanova St., 8, Vladivostok 690000, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1152\/physrev.2000.80.1.361","article-title":"Oxysterols: Modulators of cholesterol metabolism and other processes","volume":"80","author":"Schroepfer","year":"2000","journal-title":"Physiol. Revs."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.freeradbiomed.2016.10.008","article-title":"Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson\u2019s disease","volume":"101","author":"Doria","year":"2016","journal-title":"Free Radic. Biol. 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