{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:00:28Z","timestamp":1792087228893,"version":"4.4.0"},"reference-count":280,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["Ref. ED431G2019\/06"],"award-info":[{"award-number":["Ref. ED431G2019\/06"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002847","name":"Ministerio de Educaci\u00f3n, Gobierno de Chile","doi-asserted-by":"publisher","award":["1180571"],"award-info":[{"award-number":["1180571"]}],"id":[{"id":"10.13039\/501100002847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>Phenolic compounds from marine organisms are far less studied than those from terrestrial sources since their structural diversity and variability require powerful analytical tools. However, both their biological relevance and potential properties make them an attractive group deserving increasing scientific interest. The use of efficient extraction and, in some cases, purification techniques can provide novel bioactives useful for food, nutraceutical, cosmeceutical and pharmaceutical applications. The bioactivity of marine phenolics is the consequence of their enzyme inhibitory effect and antimicrobial, antiviral, anticancer, antidiabetic, antioxidant, or anti-inflammatory activities. This review presents a survey of the major types of phenolic compounds found in marine sources, as well as their reputed effect in relation to the occurrence of dietary and lifestyle-related diseases, notably type 2 diabetes mellitus, obesity, metabolic syndrome, cancer and Alzheimer\u2019s disease. In addition, the influence of marine phenolics on gut microbiota and other pathologies is also addressed.<\/jats:p>","DOI":"10.3390\/md18100501","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T09:41:01Z","timestamp":1601458861000},"page":"501","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":136,"title":["Bioactive Properties of Marine Phenolics"],"prefix":"10.3390","volume":"18","author":[{"given":"Raquel","family":"Mateos","sequence":"first","affiliation":[{"name":"Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), Spanish National Research Council (CSIC), Jos\u00e9 Antonio Nov\u00e1is 10, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1278-7782","authenticated-orcid":false,"given":"Jos\u00e9 Ricardo","family":"P\u00e9rez-Correa","sequence":"additional","affiliation":[{"name":"Department of Chemical and Bioprocess Engineering, Pontificia Universidad Cat\u00f3lica de Chile, Macul, Santiago 7810000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herminia","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"CINBIO, Department of Chemical Engineering, Faculty of Sciences, Campus Ourense, Universidade de Vigo, As Lagoas, 32004 Ourense, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1080\/00318884.2019.1640533","article-title":"Seaweeds as nutraceuticals for health and nutrition","volume":"58","author":"Shannon","year":"2019","journal-title":"Phycologia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"18107","DOI":"10.1007\/s11356-015-4907-7","article-title":"Induced production of brominated aromatic compounds in the alga Ceramium tenuicorne","volume":"22","author":"Dahlgren","year":"2015","journal-title":"Environ. 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