{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:29:18Z","timestamp":1783351758539,"version":"3.54.6"},"reference-count":134,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Marine Drugs"],"abstract":"<jats:p>Marine-derived fungi are renowned as a source of astonishingly significant and synthetically appealing metabolites that are proven as new lead chemicals for chemical, pharmaceutical, and agricultural fields. Aspergillus sydowii is a saprotrophic, ubiquitous, and halophilic fungus that is commonly found in different marine ecosystems. This fungus can cause aspergillosis in sea fan corals leading to sea fan mortality with subsequent changes in coral community structure. Interestingly, A. sydowi is a prolific source of distinct and structurally varied metabolites such as alkaloids, xanthones, terpenes, anthraquinones, sterols, diphenyl ethers, pyrones, cyclopentenones, and polyketides with a range of bioactivities. A. sydowii has capacity to produce various enzymes with marked industrial and biotechnological potential, including \u03b1-amylases, lipases, xylanases, cellulases, keratinases, and tannases. Also, this fungus has the capacity for bioremediation as well as the biocatalysis of various chemical reactions. The current work aimed at focusing on the bright side of this fungus. In this review, published studies on isolated metabolites from A. sydowii, including their structures, biological functions, and biosynthesis, as well as the biotechnological and industrial significance of this fungus, were highlighted. More than 245 compounds were described in the current review with 134 references published within the period from 1975 to June 2023.<\/jats:p>","DOI":"10.3390\/md21080441","type":"journal-article","created":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T10:25:36Z","timestamp":1691231136000},"page":"441","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Secondary Metabolites, Biological Activities, and Industrial and Biotechnological Importance of Aspergillus sydowii"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6858-7560","authenticated-orcid":false,"given":"Sabrin","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Preparatory Year Program, Department of Chemistry, Batterjee Medical College, Jeddah 21442, Saudi Arabia"},{"name":"Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaimaa","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, British University, El Sherouk City, Cairo 11837, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baiaan","family":"Alsaadi","sequence":"additional","affiliation":[{"name":"Department of Clinical Service, Pharmaceutical Care Services, King Salman Medical City, MOH, Al Madinah Al Munawwarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Althubyani","sequence":"additional","affiliation":[{"name":"Department of Clinical Service, Pharmaceutical Care Services, King Salman Medical City, MOH, Al Madinah Al Munawwarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab","family":"Awari","sequence":"additional","affiliation":[{"name":"Pharmaceutical Care Services, King Salman Medical City, MOH, Al Madinah Al Munawwarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazem","family":"Hussein","sequence":"additional","affiliation":[{"name":"Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abrar","family":"Aljohani","sequence":"additional","affiliation":[{"name":"Pharmaceutical Care Services, Medina Cardiac Center, MOH, Al Madinah Al Munawwarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumanah","family":"Albasri","sequence":"additional","affiliation":[{"name":"Pharmacy Department, Home Health Care, MOH, Al Madinah Al Munawwarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salha","family":"Faraj","sequence":"additional","affiliation":[{"name":"Pharmacy Department, King Salman Medical City, MOH, Almadinah Almunawarah 11176, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2971-6008","authenticated-orcid":false,"given":"Gamal","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1007\/s00284-021-02533-6","article-title":"Natural Products of the Fungal Genus Humicola: Diversity, Biological Activity, and Industrial Importance","volume":"78","author":"Ibrahim","year":"2021","journal-title":"Curr. Microbiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"5108","DOI":"10.1080\/14786419.2021.1919105","article-title":"Genus Thielavia: Phytochemicals, Industrial Importance and Biological Relevance","volume":"36","author":"Ibrahim","year":"2022","journal-title":"Nat. Prod. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.fitote.2018.04.012","article-title":"Biologically Active Fungal Depsidones: Chemistry, Biosynthesis, Structural Characterization, and Bioactivities","volume":"129","author":"Ibrahim","year":"2018","journal-title":"Fitoterapia"},{"key":"ref_4","first-page":"791","article-title":"\u03b3-Butyrolactones from Aspergillus Species: Structures, Biosynthesis, and Biological Activities","volume":"12","author":"Ibrahim","year":"2017","journal-title":"Nat. Prod. Commun."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"463","DOI":"10.5598\/imafungus.2014.05.02.10","article-title":"The Importance of Fungi and Mycology for Addressing Major Global Challenges","volume":"5","author":"Lange","year":"2014","journal-title":"IMA Fungus"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s11557-022-01856-3","article-title":"Exploring Potential of Aspergillus Sclerotiorum: Secondary Metabolites and Biotechnological Relevance","volume":"22","author":"Ibrahim","year":"2023","journal-title":"Mycol. Prog."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Ibrahim, S.R.M., Fadil, S.A., Fadil, H.A., Eshmawi, B.A., Mohamed, S.G.A., and Mohamed, G.A. (2022). Fungal Naphthalenones; Promising Metabolites for Drug Discovery: Structures, Biosynthesis, Sources, and Pharmacological Potential. Toxins, 14.","DOI":"10.3390\/toxins14020154"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Ghazawi, K.F., Fatani, S.A., Mohamed, S.G., Mohamed, G.A., and Ibrahim, S.R. (2023). Aspergillus nidulans\u2014Natural Metabolites Powerhouse: Structures, Biosynthesis, Bioactivities, and Biotechnological Potential. Fermentation, 9.","DOI":"10.3390\/fermentation9040325"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"451","DOI":"10.3390\/md16110451","article-title":"Diphenyl Ethers from a Marine-Derived Aspergillus sydowii","volume":"16","author":"Wang","year":"2018","journal-title":"Mar. Drugs"},{"key":"ref_10","first-page":"891","article-title":"A New Metabolite, 3-Carboxy-2, 4-Diphenyl-but-2-Enoic Anhydride, Produced by Aspergillus nidulans","volume":"47","author":"Hamasaki","year":"1983","journal-title":"Agric. Biol. Chem."},{"key":"ref_11","first-page":"37","article-title":"Two New Metabolites, Sydonic Acid and Hydroxysydonic Acid, from Aspergillus Sydowi","volume":"42","author":"Hamasaki","year":"1978","journal-title":"Agric. Biol. Chem."},{"key":"ref_12","first-page":"2181","article-title":"The Structure of Two New Metabolites, Emerin and Emericellin, from Aspergillus nidulans","volume":"39","author":"Ishida","year":"1975","journal-title":"Agric. Biol. Chem."},{"key":"ref_13","first-page":"1520","article-title":"Surviving in the Brine: A Multi-Omics Approach for Understanding the Physiology of the Halophile Fungus Aspergillus sydowii at Saturated NaCl Concentration","volume":"13","year":"2022","journal-title":"Front. Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1023\/A:1013145524136","article-title":"Characterization of Aspergillus sydowii (Thom Et Church), a Fungal Pathogen of Caribbean Sea Fan Corals","volume":"460","author":"Alker","year":"2001","journal-title":"Hydrobiologia"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1007\/s10600-017-2200-3","article-title":"A New Sydonic Acid Derivative from a Marine Derived-Fungus Aspergillus sydowii","volume":"53","author":"Xu","year":"2017","journal-title":"Chem. Nat. Compd."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00338-008-0387-2","article-title":"Fungi in Healthy and Diseased Sea Fans (Gorgonia Ventalina): Is Aspergillus sydowii always the Pathogen?","volume":"27","author":"Sabat","year":"2008","journal-title":"Coral Reefs"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1439-0507.2007.01458.x","article-title":"A Case of Onychomycosis due to Aspergillus sydowii Diagnosed using DNA Sequence Analysis","volume":"51","author":"Takahata","year":"2008","journal-title":"Mycoses"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Hayashi, A., Crombie, A., Lacey, E., Richardson, A.J., Vuong, D., Piggott, A.M., and Hallegraeff, G. (2016). Aspergillus sydowii Marine Fungal Bloom in Australian Coastal Waters, its Metabolites and Potential Impact on Symbiodinium Dinoflagellates. Mar. Drugs, 14.","DOI":"10.3390\/md14030059"},{"key":"ref_19","first-page":"1050","article-title":"Production, Purification and Characterization of A-Amylase of Aspergillus sydowii IMI 502692","volume":"20","author":"Adegoke","year":"2019","journal-title":"Plant Cell Biotechnol. Mol. Biol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"101453","DOI":"10.1016\/j.bcab.2019.101453","article-title":"Biotechnological Potential of a Novel Tannase-Acyl Hydrolase from Aspergillus sydowii using Waste Coir Residue: Aqueous Two-Phase System and Chromatographic Techniques","volume":"23","author":"Albuquerque","year":"2020","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"471","DOI":"10.3390\/jof7060471","article-title":"Keratinases Produced by Aspergillus Stelliformis, Aspergillus sydowii, and Fusarium Brachygibbosum Isolated from Human Hair: Yield and Activity","volume":"7","author":"Alwakeel","year":"2021","journal-title":"J. Fungi"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0232-4393(86)80063-4","article-title":"Lipases from Aspergillus Sydowi","volume":"141","author":"Elwan","year":"1986","journal-title":"Zent. F\u00fcr Mikrobiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1128\/aem.60.12.4620-4623.1994","article-title":"Purification and some Properties of a Xylanase from Aspergillus sydowii MG49","volume":"60","author":"Ghosh","year":"1994","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/14786419.2019.1629919","article-title":"New Pyrone and Cyclopentenone Derivatives from Marine-Derived Fungus Aspergillus sydowii SCSIO 00305","volume":"35","author":"Amin","year":"2021","journal-title":"Nat. Prod. Res."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Bu, C., Zhang, Q., Zeng, J., Cao, X., Hao, Z., Qiao, D., Cao, Y., and Xu, H. (2020). Identification of a Novel Anthocyanin Synthesis Pathway in the Fungus Aspergillus sydowii H-1. BMC Genom., 21.","DOI":"10.1186\/s12864-019-6442-2"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1080\/10286020.2022.2114464","article-title":"Two Sydowic Acid Derivatives and a Sulfonyl Metabolite from the Endophytic Fungus Aspergillus sydowii","volume":"24","author":"Chen","year":"2022","journal-title":"J. Asian Nat. Prod. Res."},{"key":"ref_27","first-page":"1053","article-title":"Structural Analysis of Sydowic Acid by X-Ray Diffraction","volume":"40","author":"Fukuyama","year":"1976","journal-title":"Agric. Biol. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1007\/s10600-017-2241-7","article-title":"Secondary Metabolites from the Marine Fungus Aspergillus sydowii","volume":"53","author":"Gao","year":"2017","journal-title":"Chem. Nat. Compd."},{"key":"ref_29","first-page":"2337","article-title":"Isolation of New Metabolites from Aspergillus Sydowi and Structure of Sydowic Acid","volume":"39","author":"Hamasaki","year":"1975","journal-title":"Agric. Biol. Chem."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0040-4039(00)71947-2","article-title":"Sydowic Acid, a New Metabolite from Aspergillus Sydowi","volume":"16","author":"Hamasaki","year":"1975","journal-title":"Tetrahedron Lett."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/ja.2011.117","article-title":"Indole Alkaloids from Marine-Derived Fungus Aspergillus sydowii SCSIO 00305","volume":"65","author":"He","year":"2012","journal-title":"J. Antibiot."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1007\/s00343-020-0049-y","article-title":"Antioxidant Bisabolane-Type Sesquiterpenoids from Algal-Derived Fungus Aspergillus sydowii EN-434","volume":"38","author":"Hu","year":"2020","journal-title":"J. Oceanol. Limnol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/mrc.4254","article-title":"New Diketopiperazine Dimer from a Filamentous Fungal Isolate of Aspergillus sydowii","volume":"53","author":"Kaur","year":"2015","journal-title":"Magn. Reson. Chem. MRC"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"669","DOI":"10.7164\/antibiotics.55.669","article-title":"A Novel Dihydroxanthenone, AGI-B4 with Inhibition of VEGF-Induced Endothelial Cell Growth","volume":"55","author":"Kim","year":"2002","journal-title":"J. Antibiot."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.fitote.2019.03.031","article-title":"Structurally Diverse Sesquiterpenoids and Polyketides from a Sponge-Associated Fungus Aspergillus sydowii SCSIO41301","volume":"135","author":"Liu","year":"2019","journal-title":"Fitoterapia"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1080\/14786419.2017.1289205","article-title":"New Metabolites from the Sponge-Derived Fungus Aspergillus sydowii J05B-7F-4","volume":"31","author":"Liu","year":"2017","journal-title":"Nat. Prod. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"6081","DOI":"10.1016\/j.tetlet.2013.08.137","article-title":"Sydowiols A\u2013C: Mycobacterium Tuberculosis Protein Tyrosine Phosphatase Inhibitors from an East China Sea Marine-Derived Fungus, Aspergillus sydowii","volume":"54","author":"Liu","year":"2013","journal-title":"Tetrahedron Lett."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.phytol.2022.09.007","article-title":"Phenol Derivatives from the Cold-Seep Fungus Aspergillus sydowii 10\u201331","volume":"52","author":"Liu","year":"2022","journal-title":"Phytochem. Lett."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.31788\/RJC.2022.1546971","article-title":"Antibacterial Compound from Marine Sponge Derived Fungus Aspergillus sydowii DC08","volume":"15","author":"Handayani","year":"2022","journal-title":"Rasayan J. Chem."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1080\/14786419.2017.1335730","article-title":"Antibacterial Constituents from Antarctic Fungus, Aspergillus sydowii SP-1","volume":"32","author":"Li","year":"2018","journal-title":"Nat. Prod. Res."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Liu, Y., Zhang, J., Li, C., Mu, X., Liu, X., Wang, L., Zhao, Y., Zhang, P., Li, X., and Zhang, X. (2019). Antimicrobial Secondary Metabolites from the Seawater-Derived Fungus Aspergillus sydowii SW9. Molecules, 24.","DOI":"10.3390\/molecules24244596"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3390\/md20070410","article-title":"Antiviral Cyclopropane Acids from Deep-Sea-Derived Fungus Aspergillus sydowii","volume":"20","author":"Niu","year":"2022","journal-title":"Mar. Drugs"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s12272-010-0401-4","article-title":"Two New Hetero-Spirocyclic \u0393-Lactam Derivatives from Marine Sediment-Derived Fungus Aspergillus Sydowi D2\u20136","volume":"33","author":"Ren","year":"2010","journal-title":"Arch. Pharm. Res."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1007\/BF02980236","article-title":"Two New Metabolites with Cytotoxicities from Deep-Sea Fungus, Aspergillus Sydowi YH11-2","volume":"30","author":"Tian","year":"2007","journal-title":"Arch. Pharm. Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/ja.2014.39","article-title":"Antimicrobial and Antiviral Sesquiterpenoids from Sponge-Associated Fungus, Aspergillus sydowii ZSDS1-F6","volume":"67","author":"Wang","year":"2014","journal-title":"J. Antibiot."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3390\/md15060191","article-title":"Asperentin B, a New Inhibitor of the Protein Tyrosine Phosphatase 1B","volume":"15","author":"Wiese","year":"2017","journal-title":"Mar. Drugs"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Yang, X., Yu, H., Ren, J., Cai, L., Xu, L., and Liu, L. (2023). Sulfoxide-Containing Bisabolane Sesquiterpenoids with Antimicrobial and Nematicidal Activities from the Marine-Derived Fungus Aspergillus sydowii LW09. J. Fungi, 9.","DOI":"10.3390\/jof9030347"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1021\/np700737g","article-title":"Cytotoxic Alkaloids and Antibiotic Nordammarane Triterpenoids from the Marine-Derived Fungus Aspergillus Sydowi","volume":"71","author":"Zhang","year":"2008","journal-title":"J. Nat. Prod."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ijbiomac.2020.01.176","article-title":"Enhanced Removal of Trichlorfon and Cd (II) from Aqueous Solution by Magnetically Separable Chitosan Beads Immobilized Aspergillus sydowii","volume":"148","author":"Zhang","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_50","first-page":"1751","article-title":"Amplified Antibiotic Potency of Two Different Drugs Combined with Biosynthesized AgNPs from Aspergillus sydowii Isolated from Sand Dunes","volume":"6","author":"Nayak","year":"2014","journal-title":"Int. J. Pharm. Tech. Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"123813","DOI":"10.1016\/j.colsurfa.2019.123813","article-title":"Enahanced Biosorption of Cu (II) by Magnetic Chitosan Microspheres Immobilized Aspergillus sydowii (MCMAs) from Aqueous Solution","volume":"581","author":"Zhang","year":"2019","journal-title":"Colloids Surf. Physicochem. Eng. Asp."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/ep.11949","article-title":"Exploration on Green Synthesis of Gold Nanoparticles by a Marine-derived Fungus Aspergillus sydowii","volume":"34","author":"Vala","year":"2015","journal-title":"Environ. Prog. Sustain. Energy"},{"key":"ref_53","first-page":"927","article-title":"Two New Cyclopentanoids from the Endophytic Fungus Aspergillus sydowii Associated with the Marine Alga Acanthophora Spicifera","volume":"1","author":"Teuscher","year":"2006","journal-title":"Nat. Prod. Commun."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1016\/j.bmc.2013.04.004","article-title":"An Epigenetic Modifier Enhances the Production of Anti-Diabetic and Anti-Inflammatory Sesquiterpenoids from Aspergillus sydowii","volume":"21","author":"Chung","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1080\/14786419.2018.1519561","article-title":"Secondary Metabolites Isolated from the Deep Sea-Derived Fungus Aspergillus sydowii C1-S01-A7","volume":"33","author":"Wang","year":"2019","journal-title":"Nat. Prod. Res."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1021\/np200374j","article-title":"Sesquiterpene and Xanthone Derivatives from the Sea Fan-Derived Fungus Aspergillus sydowii PSU-F154","volume":"74","author":"Trisuwan","year":"2011","journal-title":"J. Nat. Prod."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"104420","DOI":"10.1016\/j.bioorg.2020.104420","article-title":"Phenolic Bisabolane and Cuparene Sesquiterpenoids with Anti-Inflammatory Activities from the Deep-Sea-Derived Aspergillus sydowii MCCC 3A00324 Fungus","volume":"105","author":"Niu","year":"2020","journal-title":"Bioorg. Chem."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12934-021-01527-0","article-title":"Inducing Secondary Metabolite Production of Aspergillus sydowii through Microbial Co-Culture with Bacillus Subtilis","volume":"20","author":"Sun","year":"2021","journal-title":"Microb. Cell Factories"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1007\/s00248-022-02029-1","article-title":"Biosynthetic Profile in the Co-Culture of Aspergillus sydowii and Bacillus Subtilis to Produce Novel Benzoic Derivatives","volume":"85","author":"Sun","year":"2022","journal-title":"Microb. Ecol."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Niu, S., Yang, L., Chen, T., Hong, B., Pei, S., Shao, Z., and Zhang, G. (2020). New Monoterpenoids and Polyketides from the Deep-Sea Sediment-Derived Fungus Aspergillus sydowii MCCC 3A00324. Mar. Drugs, 18.","DOI":"10.3390\/md18110561"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Huang, Q., Wang, Y., Wu, H., Yuan, M., Zheng, C., and Xu, H. (2021). Xanthone Glucosides: Isolation, Bioactivity and Synthesis. Molecules, 26.","DOI":"10.3390\/molecules26185575"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Badiali, C., Petruccelli, V., Brasili, E., and Pasqua, G. (2023). Xanthones: Biosynthesis and Trafficking in Plants, Fungi and Lichens. Plants, 12.","DOI":"10.3390\/plants12040694"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.phytol.2013.03.012","article-title":"Xanthone Derivatives from Aspergillus sydowii, an Endophytic Fungus from the Liverwort Scapania Ciliata S. Lac and their Immunosuppressive Activities","volume":"6","author":"Song","year":"2013","journal-title":"Phytochem. Lett."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"3872","DOI":"10.1080\/14786419.2021.1892673","article-title":"Two New Pyrone Derivatives from the Mangrove-Derived Endophytic Fungus Aspergillus sydowii# 2B","volume":"36","author":"Wang","year":"2022","journal-title":"Nat. Prod. Res."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"4936","DOI":"10.1080\/14786419.2021.1913587","article-title":"Acremolin D, a New Acremolin Alkaloid from the Deep-Sea Sediment Derived Aspergillus sydowii Fungus","volume":"36","author":"Niu","year":"2022","journal-title":"Nat. Prod. Res."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1021\/np100568w","article-title":"N-Hydroxypyridones, Phenylhydrazones, and a Quinazolinone from Isaria Farinosa","volume":"74","author":"Ma","year":"2011","journal-title":"J. Nat. Prod."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/ja.2015.55","article-title":"Sydoxanthone C and Acremolin B Produced by Deep-Sea-Derived Fungus Aspergillus Sp. SCSIO Ind09F01","volume":"68","author":"Tian","year":"2015","journal-title":"J. Antibiot."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Gupta, R.C. (2011). Reproductive and Developmental Toxicology, CRC Press.","DOI":"10.1016\/B978-0-12-382032-7.10080-3"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.phytol.2018.04.023","article-title":"New Citrinin Analogues Produced by Coculture of the Marine Algal-Derived Endophytic Fungal Strains Aspergillus sydowii EN-534 and Penicillium Citrinum EN-535","volume":"25","author":"Yang","year":"2018","journal-title":"Phytochem. Lett."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"5993","DOI":"10.3390\/md12125993","article-title":"Three New Asperentin Derivatives from the Algicolous Fungus Aspergillus Sp. F00785","volume":"12","author":"Tang","year":"2014","journal-title":"Mar. Drugs"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1007\/s11426-016-0233-1","article-title":"Attractive Natural Products with Strained Cyclopropane and\/Or Cyclobutane Ring Systems","volume":"59","author":"Fan","year":"2016","journal-title":"Sci. China Chem."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Burmud\u017eija, A.Z., Mu\u0161kinja, J.M., Kosani\u0107, M.M., Rankovi\u0107, B.R., Novakovi\u0107, S.B., \u0110or\u0111evi\u0107, S.B., Stanojkovi\u0107, T.P., Baski\u0107, D.D., and Ratkovi\u0107, Z.R. (2017). Cytotoxic and Antimicrobial Activity of Dehydrozingerone based Cyclopropyl Derivatives. Chem. Biodiver., 14.","DOI":"10.1002\/cbdv.201700077"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1039\/D1NP00065A","article-title":"Biosynthesis of Cyclopropane in Natural Products","volume":"39","author":"Ma","year":"2022","journal-title":"Nat. Prod. Rep."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Lee, Y., Yoon, Y., Yoon, H., Park, H., Song, S., and Yeum, K. (2017). Dietary Anthocyanins Against Obesity and Inflammation. Nutrients, 9.","DOI":"10.3390\/nu9101089"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"4713","DOI":"10.2147\/IDR.S290835","article-title":"Antimicrobial Stewardship: Fighting Antimicrobial Resistance and Protecting Global Public Health","volume":"13","author":"Majumder","year":"2020","journal-title":"Infect. Drug Resist."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Coque, T.M., Cant\u00f3n, R., P\u00e9rez-Cobas, A.E., Fern\u00e1ndez-de-Bobadilla, M.D., and Baquero, F. (2023). Antimicrobial Resistance in the Global Health Network: Known Unknowns and Challenges for Efficient Responses in the 21st Century. Microorganisms, 11.","DOI":"10.3390\/microorganisms11041050"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"28","DOI":"10.7324\/JAPS.2020.104005","article-title":"Antimicrobial and Cytotoxic Activities of Marine Sponge-Derived Fungal Extracts Isolated from Dactylospongia sp.","volume":"10","author":"Sandrawati","year":"2020","journal-title":"J. Appl. Pharm. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"114189","DOI":"10.1016\/j.ejmech.2022.114189","article-title":"Influenza-Existing Drugs and Treatment Prospects","volume":"232","author":"Sarker","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1002\/med.21707","article-title":"Development of Anti-influenza Agents from Natural Products","volume":"40","author":"Zhang","year":"2020","journal-title":"Med. Res. Rev."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nature05482","article-title":"Mechanisms Linking Obesity to Insulin Resistance and Type 2 Diabetes","volume":"444","author":"Kahn","year":"2006","journal-title":"Nature"},{"key":"ref_81","first-page":"85","article-title":"Molecular Mechanisms of Insulin-Stimulated Glucose Uptake in Adipocytes","volume":"28","author":"Ducluzeau","year":"2002","journal-title":"Diabetes Metab."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1161\/CIRCULATIONAHA.107.721860","article-title":"Myocardial Lipid Accumulation in the Diabetic Heart","volume":"116","author":"Ruberg","year":"2007","journal-title":"Circulation"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4102\/jsava.v71i4.729","article-title":"Nematode Parasites of Vertebrates: Their Development and Transmission, RC Anderson: Book Review","volume":"71","author":"Krecek","year":"2000","journal-title":"J. S. Afr. Vet. Assoc."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1186\/s13071-019-3537-1","article-title":"An Appraisal of Natural Products Active Against Parasitic Nematodes of Animals","volume":"12","author":"Sleebs","year":"2019","journal-title":"Parasites Vectors"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1590\/S1517-83822010000400004","article-title":"Application of Microbial A-Amylase in Industry-A Review","volume":"41","author":"Souza","year":"2010","journal-title":"Braz. J. Microbiol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"576872","DOI":"10.4061\/2010\/576872","article-title":"Economic Analysis of the Production of Amylases and Other Hydrolases by Aspergillus Awamori in Solid-State Fermentation of Babassu Cake","volume":"2010","author":"Castro","year":"2010","journal-title":"Enzym. Res."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Hareeri, R.H., Aldurdunji, M.M., Abdallah, H.M., Alqarni, A.A., Mohamed, S.G., Mohamed, G.A., and Ibrahim, S.R. (2022). Aspergillus Ochraceus: Metabolites, Bioactivities, Biosynthesis, and Biotechnological Potential. Molecules, 27.","DOI":"10.3390\/molecules27196759"},{"key":"ref_88","first-page":"acmi000112","article-title":"Accelerating the Sustainable Development Goals through Microbiology: Some Efforts and Opportunities","volume":"2","author":"Fagunwa","year":"2020","journal-title":"Access Microbiol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.egypro.2017.07.269","article-title":"AgroCycle\u2013developing a Circular Economy in Agriculture","volume":"123","author":"Toop","year":"2017","journal-title":"Energy Procedia"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/ppp3.10222","article-title":"The Emerging Threat of Human-use Antifungals in Sustainable and Circular Agriculture Schemes","volume":"3","author":"Sallach","year":"2021","journal-title":"Plants People Planet"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jes.2016.08.023","article-title":"Biodegradation of Polycyclic Aromatic Hydrocarbons (PAHs) by Fungal Enzymes: A Review","volume":"51","author":"Kadri","year":"2017","journal-title":"J. Environ. Sci."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.biortech.2014.08.036","article-title":"Evaluation of the Efficiency of Trametes Hirsuta for the Removal of Multiple Pharmaceutical Compounds Under Low Concentrations Relevant to the Environment","volume":"171","author":"Haroune","year":"2014","journal-title":"Bioresour. Technol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.3389\/fmicb.2017.01792","article-title":"Overview on the Biochemical Potential of Filamentous Fungi to Degrade Pharmaceutical Compounds","volume":"8","author":"Aranda","year":"2017","journal-title":"Front. Microbiol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.biortech.2019.02.002","article-title":"First Demonstration that Ascomycetous Halophilic Fungi (Aspergillus sydowii and Aspergillus destruens) are Useful in Xenobiotic Mycoremediation Under High Salinity Conditions","volume":"279","author":"Aranda","year":"2019","journal-title":"Bioresour. Technol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"9347","DOI":"10.1038\/s41598-021-88525-9","article-title":"Genome Sequence Analysis of Deep Sea Aspergillus sydowii BOBA1 and Effect of High Pressure on Biodegradation of Spent Engine Oil","volume":"11","author":"Manisha","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.marpolbul.2017.10.023","article-title":"Biodegradation of Anthracene and several PAHs by the Marine-Derived Fungus Cladosporium Sp. CBMAI 1237","volume":"129","author":"Birolli","year":"2018","journal-title":"Mar. Pollut. Bull."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bcab.2014.06.002","article-title":"Biotransformation of Dieldrin by the Marine Fungus Penicillium Miczynskii CBMAI 930","volume":"4","author":"Birolli","year":"2015","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"109756","DOI":"10.1016\/j.ecoenv.2019.109756","article-title":"Bioremediation of Cadmium-Trichlorfon Co-Contaminated Soil by Indian Mustard (Brassica Juncea) Associated with the Trichlorfon-Degrading Microbe Aspergillus sydowii: Related Physiological Responses and Soil Enzyme Activities. Ecotoxicol","volume":"188","author":"Zhang","year":"2020","journal-title":"Environ. Saf."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s12011-016-0683-6","article-title":"Cadmium Concentration in Mother\u2019s Blood, Milk, and Newborn\u2019s Blood and its Correlation with Fatty Acids, Anthropometric Characteristics, and Mother\u2019s Smoking Status","volume":"174","author":"Olszowski","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"4280","DOI":"10.1021\/acs.jafc.6b00909","article-title":"Biodegradation of the Organophosphate Trichlorfon and its Major Degradation Products by a Novel Aspergillus sydowii PA F-2","volume":"64","author":"Tian","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"260","DOI":"10.4172\/1948-5948.1000154","article-title":"Growth Assessment of Marine-Derived Fungi in the Presence of Esfenvalerate and its Main Metabolites","volume":"6","author":"Birolli","year":"2014","journal-title":"J. Microb. Biochem. Technol."},{"key":"ref_102","first-page":"133","article-title":"Biodegradation of Chlorpyrifos by Whole Cells of Marine-Derived Fungi Aspergillus sydowii and Trichoderma sp.","volume":"7","author":"Alvarenga","year":"2015","journal-title":"J. Microb. Biochem. Technol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"112185","DOI":"10.1016\/j.marpolbul.2021.112185","article-title":"Biodegradation Pathway of the Organophosphate Pesticides Chlorpyrifos, Methyl Parathion and Profenofos by the Marine-Derived Fungus Aspergillus sydowii CBMAI 935 and its Potential for Methylation Reactions of Phenolic Compounds","volume":"166","author":"Soares","year":"2021","journal-title":"Mar. Pollut. Bull."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.chemosphere.2014.05.069","article-title":"Biodegradation of Methyl Parathion by Whole Cells of Marine-Derived Fungi Aspergillus sydowii and Penicillium Decaturense","volume":"117","author":"Alvarenga","year":"2014","journal-title":"Chemosphere"},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Mohamed, G.A., and Ibrahim, S.R.M. (2021). Untapped Potential of Marine-Associated Cladosporium Species: An Overview on Secondary Metabolites, Biotechnological Relevance, and Biological Activities. Mar Drugs, 19.","DOI":"10.3390\/md19110645"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s11557-021-01704-w","article-title":"Biologically Active Secondary Metabolites and Biotechnological Applications of Species of the Family Chaetomiaceae (Sordariales): An Updated Review from 2016 to 2021","volume":"20","author":"Ibrahim","year":"2021","journal-title":"Mycol. Prog."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Cong, B., Wang, N., Liu, S., Liu, F., Yin, X., and Shen, J. (2017). Isolation, Characterization and Transcriptome Analysis of a Novel Antarctic Aspergillus sydowii Strain MS-19 as a Potential Lignocellulosic Enzyme Source. BMC Microbiol., 17.","DOI":"10.1186\/s12866-017-1028-0"},{"key":"ref_108","doi-asserted-by":"crossref","unstructured":"Ibrahim, S.R., Choudhry, H., Asseri, A.H., Elfaky, M.A., Mohamed, S.G., and Mohamed, G.A. (2022). Stachybotrys Chartarum\u2014A Hidden Treasure: Secondary Metabolites, Bioactivities, and Biotechnological Relevance. J. Fungi, 8.","DOI":"10.3390\/jof8050504"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.3389\/fmicb.2020.573482","article-title":"Aspergillus sydowii: Genome Analysis and Characterization of Two Heterologous Expressed, Non-Redundant Xylanases","volume":"11","author":"Brandt","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s12010-007-8108-9","article-title":"Purification and Biochemical Characterization of Two Xylanases from Aspergillus sydowii SBS 45","volume":"149","author":"Nair","year":"2008","journal-title":"Appl. Biochem. Biotechnol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s40643-021-00447-6","article-title":"Current Perspective on Production and Applications of Microbial Cellulases: A Review","volume":"8","author":"Bhardwaj","year":"2021","journal-title":"Bioresour. Bioprocess."},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Ejaz, U., Sohail, M., and Ghanemi, A. (2021). Cellulases: From Bioactivity to a Variety of Industrial Applications. Biomimetics, 6.","DOI":"10.3390\/biomimetics6030044"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ibiod.2012.12.002","article-title":"Production of Cellulase by a Newly Isolated Strain of Aspergillus sydowii and its Optimization Under Submerged Fermentation","volume":"78","author":"Matkar","year":"2013","journal-title":"Int. Biodeterior. Biodegrad."},{"key":"ref_114","doi-asserted-by":"crossref","unstructured":"Ibrahim, S.R.M., Sirwi, A., Eid, B.G., Mohamed, S.G.A., and Mohamed, G.A. (2021). Bright Side of Fusarium Oxysporum: Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology. J. Fungi, 7.","DOI":"10.3390\/jof7110943"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.ijbiomac.2020.03.116","article-title":"Comprehensive Insights into Microbial Keratinases and their Implication in various Biotechnological and Industrial Sectors: A Review","volume":"154","author":"Hassan","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1080\/07388551.2016.1185388","article-title":"Microbial Keratinases: Industrial Enzymes with Waste Management Potential","volume":"37","author":"Verma","year":"2017","journal-title":"Crit. Rev. Biotechnol."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Sharma, S., and Gupta, A. (2016). Sustainable Management of Keratin Waste Biomass: Applications and Future Perspectives. Braz. Arch. Biol. Technol., 59.","DOI":"10.1590\/1678-4324-2016150684"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/anie.202006648","article-title":"Biocatalysis: Enzymatic Synthesis for Industrial Applications","volume":"60","author":"Wu","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1007\/s10126-010-9302-2","article-title":"Marine Fungi Aspergillus sydowii and Trichoderma Sp. Catalyze the Hydrolysis of Benzyl Glycidyl Ether","volume":"13","author":"Martins","year":"2011","journal-title":"Mar. Biotechnol."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10126-015-9610-7","article-title":"Biohydroxylation of (-)-ambrox\u00ae, (-)-sclareol, and (+)-sclareolide by whole cells of Brazilian marine-derived fungi","volume":"17","author":"Martins","year":"2015","journal-title":"Mar. Biotechnol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"101546","DOI":"10.1016\/j.bcab.2020.101546","article-title":"Cascate Reactions of Progesterone by Mycelia and Culture Broth from Marine-Derived Fungus Aspergillus sydowii CBMAI 935","volume":"25","author":"Porto","year":"2020","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/10242422.2021.1956909","article-title":"Regioselective and Chemoselective Biotransformation of 2\u2032-Hydroxychalcone Derivatives by Marine-Derived Fungi","volume":"41","author":"Nitschke","year":"2023","journal-title":"Biocatal. Biotransform."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1007\/s10126-013-9534-z","article-title":"Biotransformation of Methylphenylacetonitriles by Brazilian Marine Fungal Strain Aspergillus sydowii CBMAI 934: Eco-Friendly Reactions","volume":"16","author":"Seleghim","year":"2014","journal-title":"Mar. Biotechnol."},{"key":"ref_124","doi-asserted-by":"crossref","unstructured":"Zhou, B., Ma, C., Zheng, C., Xia, T., Ma, B., and Liu, X. (2020). 3-Methylxanthine Production through Biodegradation of Theobromine by Aspergillus sydowii PT-2. BMC Microbiol., 20.","DOI":"10.1186\/s12866-020-01951-z"},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1002\/chir.23078","article-title":"Enantioselective Ene-reduction of E-2-cyano-3-(Furan-2-yl) Acrylamide by Marine and Terrestrial Fungi and Absolute Configuration of (R)-2-cyano-3-(Furan-2-yl) Propanamide Determined by Calculations of Electronic Circular Dichroism (ECD) Spectra","volume":"31","author":"Jimenez","year":"2019","journal-title":"Chirality"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.bcab.2018.08.003","article-title":"Synthesis of A-Chloroacetophenones with NH4Cl\/Oxone\u00ae in Situ Followed by Bioreduction with Whole Cells of Marine-Derived Fungi","volume":"16","author":"Morais","year":"2018","journal-title":"Biocatal. Agric. Biotechnol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s10126-009-9241-y","article-title":"Biotransformation of A-Bromoacetophenones by the Marine Fungus Aspergillus sydowii","volume":"12","author":"Rocha","year":"2010","journal-title":"Mar. Biotechnol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1080\/10242422.2017.1352585","article-title":"Stereoselective Reduction of 2-Azido-1-Phenylethanone Derivatives by Whole Cells of Marine-Derived Fungi Applied to Synthesis of Enantioenriched \u0392-Hydroxy-1, 2, 3-Triazoles","volume":"35","author":"Alvarenga","year":"2017","journal-title":"Biocatal. Biotransform."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s10126-011-9419-y","article-title":"Stereoselective Bioreduction of 1-(4-Methoxyphenyl) Ethanone by Whole Cells of Marine-Derived Fungi","volume":"14","author":"Rocha","year":"2012","journal-title":"Mar. Biotechnol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/wnan.1363","article-title":"Engineering Tailored Nanoparticles with Microbes: Quo Vadis?","volume":"8","author":"Prasad","year":"2016","journal-title":"Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jab.2017.03.004","article-title":"Microbial Synthesis of Nanoparticles and their Potential Applications in Biomedicine","volume":"15","author":"Fariq","year":"2017","journal-title":"J. Appl. Biomed."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.5897\/AJB2015.14527","article-title":"A Review on Marine Based Nanoparticles and their Potential Applications","volume":"14","author":"Singh","year":"2015","journal-title":"Afr. J. Biotechnol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.colsurfb.2014.05.027","article-title":"Biosynthesis of Nanoparticles using Microbes\u2014A Review","volume":"121","author":"Hulkoti","year":"2014","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"10356","DOI":"10.1038\/s41598-021-89854-5","article-title":"Fungus-Mediated Green Synthesis of Nano-Silver using Aspergillus sydowii and its Antifungal\/Antiproliferative Activities","volume":"11","author":"Wang","year":"2021","journal-title":"Sci. Rep."}],"container-title":["Marine Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-3397\/21\/8\/441\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:26:27Z","timestamp":1760127987000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-3397\/21\/8\/441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,5]]},"references-count":134,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["md21080441"],"URL":"https:\/\/doi.org\/10.3390\/md21080441","relation":{},"ISSN":["1660-3397"],"issn-type":[{"value":"1660-3397","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,5]]}}}