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and microorganisms. These microbial inhabitants of mangrove habitats have emerged as a pivotal resource for antimicrobials and a plethora of pharmaceutically valuable compounds, spanning enzymes, antineoplastic agents, pesticides, immunosuppressants, and immunomodulators. This review delves into the recent landscape (January 2021 to May 2024, according to the time of publication) of novel secondary metabolites isolated from mangrove-associated microorganisms, analyzing 41 microbial strains that collectively yielded 165 distinct compounds. Our objective is to assess the productivity and potential of natural products derived from microbial populations within mangrove ecosystems in recent times. Notably, fungi stand out as the preeminent contributors to the emergence of these novel natural products, underscoring their pivotal role in the bioprospecting endeavors within these unique environments.<\/jats:p>","DOI":"10.3390\/md22080372","type":"journal-article","created":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T12:40:07Z","timestamp":1723812007000},"page":"372","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["New Secondary Metabolites of Mangrove-Associated Strains"],"prefix":"10.3390","volume":"22","author":[{"given":"Yunxia","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Pediatric Intensive Care Medicine, Hainan Women and Children\u2019s Medical Center, Haikou 570206, China"},{"name":"Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimin","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingmi","family":"Xiong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liman","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fandong","family":"Kong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Intensive Care Medicine, Hainan Women and Children\u2019s Medical Center, Haikou 570206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13213-012-0442-7","article-title":"Biodiversity and biotechnological potential of microorganisms from mangrove ecosystems: A review","volume":"63","author":"Thatoi","year":"2013","journal-title":"Ann. 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