{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:31:17Z","timestamp":1777523477538,"version":"3.51.4"},"reference-count":43,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2019,7,21]],"date-time":"2019-07-21T00:00:00Z","timestamp":1563667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: The aim of the study was to assess whether there were differences between apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) and diffusion-weighted imaging with background body signal suppression (DWIBS) sequences in non-prepared and prepared bowels before and after preparation with an enteric hyperosmolar agent, to assess whether ADC measurements have the potential to avoid bowel preparation and whether ADC-DWIBS has advantages over ADC-DWI. Materials and Methods: 106 adult patients without evidence of inflammatory bowel disease (IBD) underwent magnetic resonance (MR) enterography before and after bowel preparation. ADC-DWI and ADC-DWIBS values were measured in the intestinal and colonic walls demonstrating high signal intensity (SI) at DWI tracking images of b = 800 s\/mm2 before and after preparation. Results: There were significant difference (p &lt; 0.0001) in both ADC-DWI and ADC-DWIBS results between non-prepared and prepared jejunum for DWI being 1.09 \u00d7 10\u22123 mm2\/s and 1.76 \u00d7 10\u22123 mm2\/s, respectively, and for DWIBS being 0.91 \u00d7 10\u22123 mm2\/s and 1.75 \u00d7 10\u22123 mm2\/s, respectively. Both ADC-DWI and DWIBS also showed significant difference between non-prepared and prepared colon (p &lt; 0.0001), with DWI values 1.41 \u00d7 10\u22123 mm2\/s and 2.13 \u00d7 10\u22123 mm2\/s, and DWIBS\u20141.01 \u00d7 10\u22123 mm2\/s and 2.04 \u00d7 10\u22123 mm2\/s, respectively. No significant difference between ADC-DWI and ADC-DWIBS was found in prepared jejunum (p = 0.84) and prepared colon (p = 0.58), whereas a significant difference was found in non-prepared jejunum and non-prepared colon (p = 0.0001 in both samples). Conclusions: ADC between DWI and DWIBS does not differ in prepared bowel walls but demonstrates a difference in non-prepared bowel. ADC in non-prepared bowel is lower than in prepared bowel and possible overlap with the ADC range of IBD is possible in non-prepared bowel. ADC-DWIBS has no advantage over ADC-DWI in regard to IBD assessment.<\/jats:p>","DOI":"10.3390\/medicina55070394","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T02:55:37Z","timestamp":1563764137000},"page":"394","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences"],"prefix":"10.3390","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9425-7568","authenticated-orcid":false,"given":"Ilze","family":"Apine","sequence":"first","affiliation":[{"name":"Children Clinical University Hospital, LV-1004 Riga, Latvia"},{"name":"Department of Diagnostic Radiology, Riga Stradin\u2019s University, LV-1038 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monta","family":"Baduna","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Riga Stradin\u2019s University, LV-1038 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinis","family":"Pitura","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Riga Stradin\u2019s University, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juris","family":"Pokrotnieks","sequence":"additional","affiliation":[{"name":"Department of Internal Diseases, Riga Stradin\u2019s University, LV-1038 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaida","family":"Krumina","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Riga Stradin\u2019s University, LV-1038 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.gastro.2011.10.001","article-title":"Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases with Time, Based on Systematic Review","volume":"142","author":"Molodecky","year":"2012","journal-title":"Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"786802","DOI":"10.1155\/2015\/786802","article-title":"MRI for Crohn\u2019s Disease: Present and Future","volume":"2015","author":"Yoon","year":"2015","journal-title":"Biomed. 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