{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:21:22Z","timestamp":1790713282598,"version":"4.1.0"},"reference-count":30,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:00:00Z","timestamp":1564531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: Tumor-related vertebral compression fractures often result in severe back pain as well as progressive neurologic impairment and additional morbidities. The fixation of these fractures is essential to obtain good pain relief and to improve the patients\u2019 quality of life. Thus far, several spine implants have been developed and studied. The aims of this review were to describe the implants and the techniques proposed to treat cancer-related vertebral compression fractures and to compile their safety and efficacy results. Materials and Methods: A systematic MEDLINE\/PubMed literature search was performed, time period included articles published between January 2000 and March 2019. Original articles were selected based on their clinical relevance. Results: Four studies of interest and other cited references were analyzed. These studies reported significant pain and function improvement as well as kyphotic angle and vertebral height restoration and maintain for every implant and technique investigated. Conclusions: Although good clinical performance is reported on these devices, the small numbers of studies and patients investigated draw the need for further larger evaluation before drawing a definitive treatment decision tree to guide physicians managing patients presenting with neoplastic vertebral compression fracture.<\/jats:p>","DOI":"10.3390\/medicina55080426","type":"journal-article","created":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T11:37:07Z","timestamp":1564573027000},"page":"426","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Innovative Spine Implants for Improved Augmentation and Stability in Neoplastic Vertebral Compression Fracture"],"prefix":"10.3390","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1058-0884","authenticated-orcid":false,"given":"Francois H.","family":"Cornelis","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, Department of Radiology, Tenon Hospital, 4 rue de la Chine, 75020 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quentin","family":"Joly","sequence":"additional","affiliation":[{"name":"Hyprevention, Clinical Research, 33604 Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maud","family":"Nouri-Neuville","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Department of Radiology, Tenon Hospital, 4 rue de la Chine, 75020 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Ben-Ammar","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Department of Radiology, Tenon Hospital, 4 rue de la Chine, 75020 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Kastler","sequence":"additional","affiliation":[{"name":"Department of Adult Radiology, Necker University Hospital, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Kastler","sequence":"additional","affiliation":[{"name":"Neuroradiology and MRI unit, Grenoble University Hospital, 38700 La Tronche, France"},{"name":"University of Grenoble Alpes, Grenoble Institute des Neurosciences, Inserm, U1216 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Amoretti","sequence":"additional","affiliation":[{"name":"Department of Radiology, Centre Hospitalier Universitaire de Nice, H\u00f4pital Pasteur 2, 30 Voie Romaine, 06000 Nice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Hauger","sequence":"additional","affiliation":[{"name":"Department of Radiology, Centre Hospitalier Universitaire de Bordeaux, 33000 Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,7,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4184\/asj.2014.8.5.605","article-title":"Compression fractures and impact on US healthcare resource utilization","volume":"8","author":"Hazzard","year":"2014","journal-title":"Asian Spine J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.otsr.2016.01.024","article-title":"Severe pathological fractures caused by vertebral hemangiomas with posterior decompression, bone cement augmentation and internal fixation","volume":"102","author":"Li","year":"2016","journal-title":"Orthop. 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