{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T20:06:28Z","timestamp":1793736388800,"version":"4.6.1"},"reference-count":100,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T00:00:00Z","timestamp":1567382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Sexual function worsens with advancing menopause status. The most frequently reported symptoms include low sexual desire (40\u201355%), poor lubrication (25\u201330%) and dyspareunia (12\u201345%), one of the complications of genitourinary syndrome of menopause (GSM). Declining levels of sex steroids (estrogens and androgens) play a major role in the impairment of sexual response; however, psychological and relational changes related with aging and an increase in metabolic and cardiovascular comorbidities should also be taken into account. Although first-line therapeutic strategies for menopause-related sexual dysfunction aim at addressing modifiable factors, many hormonal and non-hormonal, local and systemic treatment options are currently available. Treatment should be individualized, taking into account the severity of symptoms, potential adverse effects and personal preferences.<\/jats:p>","DOI":"10.3390\/medicina55090559","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T03:06:14Z","timestamp":1567479974000},"page":"559","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":131,"title":["Sexual Health in Menopause"],"prefix":"10.3390","volume":"55","author":[{"given":"Irene","family":"Scavello","sequence":"first","affiliation":[{"name":"Andrology, Women\u2019s Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical, and Biomedical Sciences \u201cMario Serio\u201d, University of Florence, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Maseroli","sequence":"additional","affiliation":[{"name":"Andrology, Women\u2019s Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical, and Biomedical Sciences \u201cMario Serio\u201d, University of Florence, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenza","family":"Di Stasi","sequence":"additional","affiliation":[{"name":"Andrology, Women\u2019s Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical, and Biomedical Sciences \u201cMario Serio\u201d, University of Florence, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Vignozzi","sequence":"additional","affiliation":[{"name":"Andrology, Women\u2019s Endocrinology and Gender Incongruence Unit, Department of Experimental, Clinical, and Biomedical Sciences \u201cMario Serio\u201d, University of Florence, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Petraglia, F., and Fauser, B.C.J.M. 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