{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:44:46Z","timestamp":1791319486442,"version":"4.3.1"},"reference-count":71,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Seasonal allergic rhinoconjunctivitis (SAR) affects millions of people worldwide, particularly in childhood and adolescence. Pollen food allergy syndrome (PFAS) is a common adverse reaction occurring few minutes after the consumption of vegetable foods in patients with pollen-induced SAR. PFAS has rarely been investigated in the pediatric population, as it has been mainly examined as an adult disease. Recent studies suggested that PFAS might be more frequent in childhood than previously recognized. The present review aims to give an overview of the epidemiology, pathophysiology, diagnosis, management and prognosis of PFAS in children with SAR-induced by pollens.<\/jats:p>","DOI":"10.3390\/medicina55100641","type":"journal-article","created":{"date-parts":[[2019,9,27]],"date-time":"2019-09-27T03:03:15Z","timestamp":1569553395000},"page":"641","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Pollen-Food Allergy Syndrome: A not so Rare Disease in Childhood"],"prefix":"10.3390","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2145-3776","authenticated-orcid":false,"given":"Carla","family":"Mastrorilli","sequence":"first","affiliation":[{"name":"Pediatric and Emergency Operative Unit, Policlinic Consortium University Hospital-Pediatric Hospital \u201cGiovanni XXIII\u201d, 70126 Bari, Italy"},{"name":"Pediatric Clinic, University Children\u2019s Hospital, Medicine and Surgery Department, University of Parma, 43100 Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Cardinale","sequence":"additional","affiliation":[{"name":"Pediatric and Emergency Operative Unit, Policlinic Consortium University Hospital-Pediatric Hospital \u201cGiovanni XXIII\u201d, 70126 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8243-9727","authenticated-orcid":false,"given":"Arianna","family":"Giannetti","sequence":"additional","affiliation":[{"name":"Pediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Caffarelli","sequence":"additional","affiliation":[{"name":"Pediatric Clinic, University Children\u2019s Hospital, Medicine and Surgery Department, University of Parma, 43100 Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1111\/all.12666","article-title":"Position paper of the EAACI: Food allergy due to immunological cross-reactions with common inhalant allergens","volume":"70","author":"Werfel","year":"2015","journal-title":"Allergy"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.anai.2009.11.007","article-title":"Oral allergy syndrome: A clinical, diagnostic, and therapeutic challenge","volume":"104","author":"Webber","year":"2010","journal-title":"Ann. 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