{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:37:17Z","timestamp":1788316637600,"version":"build-2803163510"},"reference-count":20,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,9]],"date-time":"2020-02-09T00:00:00Z","timestamp":1581206400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Skin cancer is one of the most frequently diagnosed malignancies. The main goal of the therapeutic management is total excision with the prevention of recurrence and metastasis. The quality of life of the patients with skin cancer is affected by the morbidity risk, surgery, and cosmetic or functional aspects. The aim of this study was to evaluate the quality of life of patients with skin cancer prior to and post surgical intervention. Material and methods: We performed a prospective study on 247 patients with skin tumors. Quality of life was evaluated through an initial questionnaire that was given to all consenting patients. This was used to determine patients\u2019 mobility, selfcare, normal activities, pain, and despair, using a five-point Likert scale. The general autoperceived health state was also recorded using a 100-point scale. The study included the responses of all patients at hospital admission, after one month of surgery, and after one year of surgery. Results: In patients with squamous cell carcinoma (SCC), the general health state indicator statistically significantly decreased one month after surgery and increased at one-year follow-up. In malignant melanoma (MM) patients, mobility, selfcare, normal activities, and discomfort presented a decrease in values one year after surgery, compared to the values registered at hospital admission. In patients with basal cell carcinoma (BCC), all indicators of quality of life presented an impaired value one year after surgery, after a decreasing trend. The general health state indicator statistically significantly increased one month after surgery and after one year. Conclusions: Surgery is one of the main steps in treating skin cancer. It has a great impact on patients\u2019 quality of life because of pain andthe effect on mobility and normal activities. Skin cancers influence the quality of life of patients both psychologicallyand physically.<\/jats:p>","DOI":"10.3390\/medicina56020066","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T11:48:51Z","timestamp":1581335331000},"page":"66","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Quality of Life in Patients with Surgically Removed Skin Tumors"],"prefix":"10.3390","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9376-6774","authenticated-orcid":false,"given":"Laura","family":"R\u0103ducu","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Clinical Emergency Hospital \u201cProf. Dr. Agrippa Ionescu\u201d, 011356 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Medicine \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaida","family":"Avino","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Clinical Emergency Hospital \u201cProf. Dr. Agrippa Ionescu\u201d, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3881-4574","authenticated-orcid":false,"given":"Raluca","family":"Purnichescu Purtan","sequence":"additional","affiliation":[{"name":"Department of Mathematical Methods and Models, Faculty of Applied Sciences, University Politehnica of Bucharest, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andra-Elena","family":"Balcangiu-Stroescu","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Emergency University Hospital Bucharest, 050098 Bucharest, Romania"},{"name":"Discipline of Physiology, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, Bucharest, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Gabriela","family":"B\u0103lan","sequence":"additional","affiliation":[{"name":"Discipline of Physiology, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, Bucharest, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia","family":"Timofte","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Emergency University Hospital Bucharest, 050098 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorin","family":"Ionescu","sequence":"additional","affiliation":[{"name":"Discipline of Internal Medicine I and Nephrology, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Nephrology, Emergency University Hospital Bucharest, 050098 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian-Radu","family":"Jecan","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Clinical Emergency Hospital \u201cProf. Dr. Agrippa Ionescu\u201d, 011356 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Medicine \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.soncn.2013.06.002","article-title":"Skin cancer: An overview of epidemiology and risk factors","volume":"29","author":"Gordon","year":"2013","journal-title":"Semin. Oncol. Nurs."},{"key":"ref_2","first-page":"1138","article-title":"Patient-reported health outcomes in patients with non-melanoma skin cancer and actinic keratosis: Results from a large-scale observational study analysing effects of diagnoses and disease progression","volume":"32","author":"Novak","year":"2018","journal-title":"JEADV"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s13555-014-0049-y","article-title":"Actinic keratosis: Rationale and management","volume":"4","author":"Dodds","year":"2014","journal-title":"Dermatol. Ther."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Avil\u00e9s Izquierdo, J.A., Molina L\u00f3pez, I., Sobrini Morillo, P., M\u00e1rquez Rodas, I., and Mercader Cidoncha, E. (2019). Utility of PET\/CT in patients with stage I\u2013III melanoma. Clin. Transl. Oncol.","DOI":"10.1007\/s12094-019-02252-2"},{"key":"ref_5","first-page":"e420","article-title":"Longterm quality of life after oncologic surgery and microvascular free flap reconstruction in patients with oral squamous cell carcinoma","volume":"21","author":"Peisker","year":"2016","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1007\/s11136-017-1532-6","article-title":"Comparison of quality of life among long-term melanoma survivors and non-melanoma controls: A cross-sectional study","volume":"26","author":"Vogel","year":"2017","journal-title":"Qual. Life Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s13187-018-1368-y","article-title":"Quality of life in patients with non-melanoma skin cancer: Implications for healthcare education services and supports","volume":"34","author":"Abedini","year":"2019","journal-title":"J. Cancer Educ."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1001\/jamainternmed.2016.5008","article-title":"Skin Cancer-The Importance of Prevention","volume":"176","author":"Linos","year":"2016","journal-title":"JAMA Intern. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Fahradyan, A., Howell, A.C., Wolfswinkel, E.M., Tsuha, M., Sheth, P., and Wong, A.K. (2017). Updates on the Management of Non-Melanoma Skin Cancer (NMSC). Healthcare, 5.","DOI":"10.3390\/healthcare5040082"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/ajd.12205","article-title":"Quality of life in non-melanoma skin cancer","volume":"56","author":"Gaulin","year":"2015","journal-title":"Australas. J. Dermatol."},{"key":"ref_11","first-page":"11","article-title":"Relationship between visibility of skin condition and quality of life","volume":"52","author":"Fessa","year":"2011","journal-title":"Australas. J. Dermatol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0039-6109(02)00205-0","article-title":"Surgical treatment of malignant melanoma","volume":"83","author":"Essner","year":"2003","journal-title":"Surg. Clin. N. Am."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.37358\/RC.18.10.6644","article-title":"Nefopam and its role in modulating acute and chronic pain","volume":"69","author":"Tiglis","year":"2018","journal-title":"Rev. Chim. (Bucharest)"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"408","DOI":"10.31925\/farmacia.2018.3.4","article-title":"New approaches and perspectives for the pharmacological treatment of arterial hypertension","volume":"66","author":"Diaconu","year":"2018","journal-title":"Farmacia"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.37358\/RC.18.11.6695","article-title":"Diabetic nephropathy: A concise assessment of the causes, risk factors and implications in diabetic patients","volume":"69","author":"Tanasescu","year":"2018","journal-title":"Rev. Chim. (Bucharest)"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"354","DOI":"10.37358\/RC.18.2.6106","article-title":"A rare case of a lower lip merkel cell carcinoma diagnosis and treatment","volume":"69","author":"Raducu","year":"2018","journal-title":"Rev. Chim. (Bucharest)"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.37358\/RC.17.9.5834","article-title":"Use of polyhexanidine in treating chronic wounds","volume":"68","author":"Raducu","year":"2017","journal-title":"Rev. Chim. (Bucharest)"},{"key":"ref_18","first-page":"525","article-title":"Skin cancer and quality of life: Assessment with the dermatology life quality index","volume":"30","author":"Rhee","year":"2004","journal-title":"Dermatol. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1111\/jdv.15487","article-title":"Quality of life measurement in skin cancer patients: Literature review and position paper of the european academy of dermatology and venereology task forces on quality of life and patient oriented outcomes, melanoma and non-melanoma skin cancer","volume":"33","author":"Chernyshov","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1046\/j.1087-0024.2003.09118.x","article-title":"A quality-of-life study in high-risk (thickness\u2009\u2265\u20092 mm) cutaneous melanoma patients in a randomized trial of 1-cm versus 3-cm surgical excision margins","volume":"9","author":"Nolan","year":"2004","journal-title":"J. Investig. Dermatol. Symp. Proc."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/2\/66\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T08:56:09Z","timestamp":1760172969000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/2\/66"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,9]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2]]}},"alternative-id":["medicina56020066"],"URL":"https:\/\/doi.org\/10.3390\/medicina56020066","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,9]]}}}