{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T04:50:32Z","timestamp":1773809432326,"version":"3.50.1"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,14]],"date-time":"2020-02-14T00:00:00Z","timestamp":1581638400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: Performing physical exercise after a colorectal cancer diagnosis is associated with lower mortality related to the tumor itself. In order to improve physical recovery after elective surgery, there are no specific exercise protocols after discharge from the hospital. The purpose of this study is to show the preliminary results of an exercise program after colorectal cancer surgery. Materials and Methods: Six patients with non-metastatic colorectal adenocarcinoma addressed to respective laparoscopic were randomly assigned to a mixed supervised\/home-based exercise program for six months and compared to a control group without exercise. To assess the effectiveness of the program, functional and body composition parameters were evaluated. Results: Three months after surgery, the exercise group increased flexibility (p &lt;0.01, ES = 0.33), strength of lower limbs (p &lt;0.01, ES = 0.42) and aerobic capacity (p &lt;0.01, ES = 0.28). After surgery, the six patients experienced a significant reduction in body mass index (BMI) and free fat mass. More specifically, fat mass reached the lowest values, with a concomitant increase in cell mass after six months (p &lt;0.01, ES = 0.33). This did not occur in the control group. Conclusions: Colorectal cancer treatment induces a reduction in physical function, particularly during the first six months after treatment. A mixed exercise approach appears promising in countering this process after colorectal cancer surgery.<\/jats:p>","DOI":"10.3390\/medicina56020078","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T10:10:25Z","timestamp":1582020625000},"page":"78","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Preliminary Results of an Exercise Program After Laparoscopic Resective Colorectal Cancer Surgery in Non-Metastatic Adenocarcinoma: A Pilot Study of a Randomized Control Trial"],"prefix":"10.3390","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8842-0354","authenticated-orcid":false,"given":"Gabriele","family":"Mascherini","sequence":"first","affiliation":[{"name":"Sport and Exercise Medicine Unit, Dipartimento di Medicina Sperimentale e Clinica, Universit\u00e0 degli Studi di Firenze, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Novella","family":"Ringressi","sequence":"additional","affiliation":[{"name":"Multidisciplinary Oncology Group, Dipartimento di Medicina Sperimentale e Clinica, Universit\u00e0 degli Studi di Firenze, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0517-9110","authenticated-orcid":false,"given":"Jorge","family":"Castizo-Olier","sequence":"additional","affiliation":[{"name":"Tecno Campus Matar\u00f3-Maresme, EscuelaSuperior de Ciencias de la Salud, 08302 Matar\u00f3, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4100-8765","authenticated-orcid":false,"given":"Georgian","family":"Badicu","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Special Motricity, Faculty of Physical Education and Mountain Sports, Transilvania University of Brasov, 500068 Brasov, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3463-6643","authenticated-orcid":false,"given":"Alfredo","family":"Irurtia","sequence":"additional","affiliation":[{"name":"Departament de la Presid\u00e8ncia, InstitutNacional d\u2019Educaci\u00f3F\u00edsica de Catalunya (INEFC), 08038 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2981-0424","authenticated-orcid":false,"given":"Laura","family":"Stefani","sequence":"additional","affiliation":[{"name":"Sport and Exercise Medicine Unit, Dipartimento di Medicina Sperimentale e Clinica, Universit\u00e0 degli Studi di Firenze, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2054-8650","authenticated-orcid":false,"given":"Giorgio","family":"Galanti","sequence":"additional","affiliation":[{"name":"Sport and Exercise Medicine Unit, Dipartimento di Medicina Sperimentale e Clinica, Universit\u00e0 degli Studi di Firenze, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2963-4085","authenticated-orcid":false,"given":"Antonio","family":"Taddei","sequence":"additional","affiliation":[{"name":"Multidisciplinary Oncology Group, Dipartimento di Medicina Sperimentale e Clinica, Universit\u00e0 degli Studi di Firenze, 50134 Firenze, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,14]]},"reference":[{"key":"ref_1","unstructured":"AIOM, AIRTUM (2019, November 04). 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