{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:34:47Z","timestamp":1792373687538,"version":"4.4.0"},"reference-count":25,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: Dupuytren\u2019s contracture is a chronic fibroproliferative hand disorder with a varying pattern of genetic predisposition across different regions and populations. Traumatic events have been found to have influence on the development of this illness and are likely to trigger different clinical forms of this disease. The aim of this study was to evaluate the phenomenon of development of Dupuytren\u2019s contracture (DC) following an acute injury to the hand, and to observe the incidence and clinical diversity of such cases in daily clinical practice. Materials and Methods: We collected data of patients presenting with primary Dupuytren\u2019s contracture in the Lithuanian population and evaluated the occurrence and clinical manifestation of this specific type of DC, arising following acute hand trauma. The diagnosis of DC was based on clinical signs and physical examination. Digit contractures were measured by goniometry, and the staging was done according to Tubiana classification. Injury-induced (injury-related) cases were identified using the \u201cCriteria for recognition of Dupuytren\u2019s contracture after acute injury\u201d (established by Elliot and Ragoowansi). Results: 29 (22%) of a total of 132 cases were injury-induced DCs. Twenty-six of 29 patients in this group presented with stage I\u2013II contractures. Duration of symptoms was 6 (SD 2.2) and 3.8 (SD 2.2) years in the injury-related and injury-unrelated DC groups, respectively. Mean age on the onset of symptoms in the injury-induced and non-injury-induced groups was 52 (SD 10.7) and 56 (SD 10.9), respectively. Patients from both groups expressed strong predisposition towards development of DC. Conclusions: Around one-fifth of patients seeking treatment for primary Dupuytren\u2019s contracture seemed to suffer from injury-induced Dupuytren\u2019s contracture. We noted that injury to the wrist and hand seems to trigger the development of less progressive Dupuytren\u2019s contracture in younger age. Prospective randomized studies are required to confirm our findings.<\/jats:p>","DOI":"10.3390\/medicina56070323","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T09:04:59Z","timestamp":1593507899000},"page":"323","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dupuytren\u2019s Contracture: Incidence of Injury-Induced Cases and Specific Clinical Expression"],"prefix":"10.3390","volume":"56","author":[{"given":"Gediminas","family":"Samul\u0117nas","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Lithuanian University of Health Sciences, Eiveni\u0173 str.2, LT 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rytis","family":"Rimdeika","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Lithuanian University of Health Sciences, Eiveni\u0173 str.2, LT 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u0119stutis","family":"Braziulis","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Lithuanian University of Health Sciences, Eiveni\u0173 str.2, LT 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mantas","family":"Fomkinas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Lithuanian University of Health Sciences, Eiveni\u0173 str. 2, LT 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rokas","family":"Pa\u0161kevi\u010dius","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Lithuanian University of Health Sciences, Eiveni\u0173 str. 2, LT 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,30]]},"reference":[{"key":"ref_1","unstructured":"(2020, February 05). UpToDate.com. Available online: https:\/\/www.uptodate.com\/contents\/dupuytrens-contracture."},{"key":"ref_2","unstructured":"(2020, February 05). BMJ Best Practice. Available online: https:\/\/bestpractice.bmj.com\/topics\/en-us\/983."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0140-6736(03)13871-8","article-title":"Guillaume Dupuytren and finger contractures","volume":"362","author":"Gudmundsson","year":"2003","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0895-4356(99)00145-6","article-title":"Epidemiology of Dupuytren\u2019s disease: Clinical, serological, and social assessment. The Reykjavik Study","volume":"53","author":"Gudmundsson","year":"2000","journal-title":"J. Clin. Epidemiol."},{"key":"ref_5","first-page":"695","article-title":"The prevalence of Dupuytren\u2019s disease in Norway. A study in a representative population sample of the municipality of Haugesund","volume":"138","author":"Mikkelsen","year":"1978","journal-title":"Acta Chir. Scand."},{"key":"ref_6","first-page":"57","article-title":"Contractions of the fingers and toes; their varieties, pathology and treatment","volume":"2","author":"Anderson","year":"1891","journal-title":"Lancet"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/J.JHSB.2004.08.002","article-title":"Dupuytren\u2019s disease secondary to acute injury, infection or operation distal to the elbow in the ipsilateral upper limb a historical review","volume":"30B","author":"Elliot","year":"2005","journal-title":"J. Hand Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.5694\/j.1326-5377.1968.tb29164.x","article-title":"Dupuytren\u2019s contracture and specific injury","volume":"1","author":"Hueston","year":"1968","journal-title":"Med. J. Aust."},{"key":"ref_9","unstructured":"McFarlane, R.M., McGrouther, D.A., and Flint, M.H. (1990). A single injury to the hand. Dupuytren\u2019s Disease: Biology and Treatment, Churchill Livingstone."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/occmed\/42.3.155","article-title":"Vibration white finger and Dupuytren\u2019s contracture: Are they related?","volume":"42","author":"Thomas","year":"1992","journal-title":"Occup. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/(SICI)1097-0274(199605)29:5<521::AID-AJIM12>3.0.CO;2-2","article-title":"Can Dupuytren\u2019s contracture be work-related: Review of the evidence","volume":"29","author":"Liss","year":"1998","journal-title":"Am. J. Indust. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0190-9622(99)70415-9","article-title":"Development of Peyronie\u2019s and Dupuytren\u2019s diseases in an individual after single episodes of trauma: A case report and review of the literature","volume":"41","author":"Connelly","year":"1999","journal-title":"J. Am. Acad. Derm."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1136\/bjsm.2004.015792","article-title":"Can rock climbing lead to Dupuytren\u2019s disease?","volume":"39","author":"Logan","year":"2005","journal-title":"Br. J. Sports Med."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Descatha, A., Jauffret, P., Chastang, J.F., Roquelaure, Y., and Leclerc, A. (2011). Should we consider Dupuytren\u2019s contracture as work-related? A review and meta-analysis of an old debate. BMC Musculoskelet. Disord., 12.","DOI":"10.1186\/1471-2474-12-96"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/ajim.20542","article-title":"Dupuytren\u2019s disease: Personal factors and occupational exposure","volume":"5","author":"Lucas","year":"2008","journal-title":"Am. J. Ind. Med."},{"key":"ref_16","unstructured":"Hueston, J.T., and Tubiana, R. (1974). The relationship of trauma and Dupuytren\u2019s contracture. Dupuytren\u2019s Disease, Grune & Stratton."},{"key":"ref_17","first-page":"116","article-title":"Dupuytren\u2019s contracture. The aetiological role of trauma","volume":"5","author":"Zachariae","year":"1971","journal-title":"Scand. J. Plast. Reconstr. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jhsb.2003.08.012","article-title":"The role of manual occupation in the aetiology of Dupuytren\u2019s disease in men in England and Wales","volume":"29","author":"Khan","year":"2001","journal-title":"J. Hand Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/J.JHSB.2005.08.004","article-title":"Non-Dupuytren\u2019s disease of the palmar fascia","volume":"30B","author":"Rayan","year":"2005","journal-title":"J. Hand Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/J.JHSE.2007.06.005","article-title":"Dupuytren\u2019s disease following acute injury in Japanese patients: Dupuytren\u2019s disease or not?","volume":"32","author":"Abe","year":"2007","journal-title":"J. Hand Surg. Eur."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.hcl.2018.03.002","article-title":"Risk factors, Disease Associations, and Dupuytren Diathesis","volume":"34","author":"Hindocha","year":"2018","journal-title":"Hand Clin."},{"key":"ref_22","first-page":"66","article-title":"Manual labor and Dupuytren disease. The results of a computerized survey in the field of iron metallurgy","volume":"2","author":"Wagner","year":"1983","journal-title":"Ann. Chir. Main."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0266-7681(96)80050-7","article-title":"Dupuytren\u2019s disease occurring after a surgical injury to the hand","volume":"21B","author":"Lanzetta","year":"1996","journal-title":"J. Hand Surg. Eur. Vol."},{"key":"ref_24","first-page":"38","article-title":"Manifestation of Dupuytren nodules following fracture of the distal radius","volume":"47","author":"Wichelhaus","year":"2015","journal-title":"Handchir. Mikrochir. Plast. Chir."},{"key":"ref_25","first-page":"1211","article-title":"Trauma as a Possible Cause of Duouytren\u2019s Disease","volume":"173","author":"Klingenberg","year":"2011","journal-title":"Ugeskr. Laeger."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/7\/323\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:44:50Z","timestamp":1760175890000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/7\/323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":25,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7]]}},"alternative-id":["medicina56070323"],"URL":"https:\/\/doi.org\/10.3390\/medicina56070323","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,30]]}}}