{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:09:13Z","timestamp":1790640553203,"version":"4.1.0"},"reference-count":22,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T00:00:00Z","timestamp":1598140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Since the first use of ventricular assist devices (VADs) as bridge to recovery and bridge to cardiac transplantation in the early 1990s, significant technological advances have transformed VAD implantation into a routine destination therapy. With improved survival, many patients present for cardiac surgery for conditions not directly related to their permanent mechanical circulatory support. The aim of this study was to analyze the indications and outcomes of non-cardiac surgeries (NCSs) of left ventricular assist device (LVAD) patients in tertiary center. Material and Methods: We present a single-center experience after 151 LVAD implantations in 138 consecutive patients between 2012\u20132019 who had to undergo NCS during a follow-up period of 37 +\/\u2212 23.4 months on left ventricular assist device (LVAD). Results: A total of 105 procedures was performed in 63 LVAD recipients, resulting in peri-operative mortality of 3.8%. Twenty-five (39.7%) of patients underwent multiple surgeries. We found no significant difference in cumulative survival associated with the performed surgical interventions (p = 0.469). Conclusion: We demonstrated good overall clinical outcomes in LVAD patients undergoing NCS. With acceptable peri-operative mortality, NCS can be safely performed in LVAD patients on long-term support.<\/jats:p>","DOI":"10.3390\/medicina56090424","type":"journal-article","created":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T21:28:06Z","timestamp":1598218086000},"page":"424","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is it Safe for Patients with Left Ventricular Assist Devices to Undergo Non-Cardiac Surgery?"],"prefix":"10.3390","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8245-4457","authenticated-orcid":false,"given":"Rafal","family":"Berger","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"Nemeth","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Salewski","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Sandoval Boburg","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metesh","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Glenfield Hospital, Leicester LE3 9QP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Weymann","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Zhigalov","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastian","family":"Schmack","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital of Essen, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-2996","authenticated-orcid":false,"given":"Michel Pompeu B. O.","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery at the Pronto Socorro Cardiol\u00f3gico de Pernambuco (PROCAPE), 74970-240 Recife, PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Schlensak","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4226-3004","authenticated-orcid":false,"given":"Aron-Frederik","family":"Popov","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, University Hospital of T\u00fcbingen, 72070 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/1089253213506788","article-title":"Management of patients with implanted ventricular assist devices for noncardiac surgery: A clinical review","volume":"18","author":"Hessel","year":"2014","journal-title":"Semin. 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