{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T15:45:58Z","timestamp":1773243958495,"version":"3.50.1"},"reference-count":53,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T00:00:00Z","timestamp":1599177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: Anatomical dissection is an indispensable means of acquiring knowledge about the variability of the human body. We detected the co-existence of several arterial variations within one female anatomic specimen during routine anatomical dissection. The aim of this study was to evaluate if this status is a regular pattern in any of other vertebrates. Materials and Methods: Besides of a meticulous anatomic dissection, we performed a literature review concerning the frequency, the phylogenesis, and ontogenesis of all of these variations. Results: Exceptionally, the middle colic artery arose from an extraordinarily divided celiac trunk. The kidneys received three polar arteries. On the left side, a corona mortis replaced the obturator artery. The aortic arch gave rise to a bicarotid trunk, and the right subclavian artery originated and coursed as a typical lusorial artery leading to a non-recurrent laryngeal nerve on the right side. Furthermore, variations of the branches of the thyrocervical trunk were found to be present. Extraordinarily, in their cervical portion both internal carotid arteries gave rise to two arteries each. All of these variations developed within two to three weeks, around the sixth week of gestation. It was not possible to ascribe all or even one of the variations to a singular species of vertebrates. Conclusion: Apparently, arterial variations are frequently a result of random development. Medical professionals must always be aware of anatomical variations; the absence of such awareness would create major difficulties during surgery. The present case confirms the relevance of anatomical dissection, particularly for medical students.<\/jats:p>","DOI":"10.3390\/medicina56090449","type":"journal-article","created":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T11:24:24Z","timestamp":1599218664000},"page":"449","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A Phylogenetic and Ontogenetic Perspective of the Unique Accumulation of Arterial Variations in One Human Anatomic Specimen"],"prefix":"10.3390","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8015-0740","authenticated-orcid":false,"given":"Bettina","family":"Pretterklieber","sequence":"first","affiliation":[{"name":"Division of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, A-1090 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2570-2730","authenticated-orcid":false,"given":"Michael L.","family":"Pretterklieber","sequence":"additional","affiliation":[{"name":"Division of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, A-1090 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1002\/ca.21197","article-title":"Thoughts on human variations","volume":"24","author":"Bergmann","year":"2011","journal-title":"Clin. Anat."},{"key":"ref_2","unstructured":"Bergmann, R.A., Afifi, A.K., and Miyauchi, R. (2018). Illustrated Encyclopedia of Human Anatomic Variation, University of Iowa."},{"key":"ref_3","first-page":"1","article-title":"Congenital anomalies of the arteries and veins of the human body with bibliography","volume":"22","author":"Poynter","year":"1922","journal-title":"Univ. Stud. Univ. Nebraska"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Lippert, H., and Pabst, R. (1985). Arterial Variations in Man. Classification and Frequency, J. F. Bergmann Verlag.","DOI":"10.1007\/978-3-642-80508-0"},{"key":"ref_5","unstructured":"Michels, N.A. (1955). Blood Supply and Anatomy of the Upper Abdominal Organs, Lippincott."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/ca.980080408","article-title":"Anomalous origins of colic arteries","volume":"8","year":"1995","journal-title":"Clin. Anat."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s00276-006-0081-4","article-title":"A singular pancreatico-colic artery: Anatomical report and clinical implications","volume":"28","author":"Barberini","year":"2006","journal-title":"Surg. Radiol. Anat."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1159\/000144446","article-title":"Variet\u00e4t des Truncus coeliacus und seiner Anastomosen mit der Arteria mesenterica superior","volume":"92","author":"Feigl","year":"1975","journal-title":"Acta Anat."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1007\/s00247-010-1727-2","article-title":"Replaced middle colic artery originating from the coeliac trunk","volume":"40","author":"Maleux","year":"2010","journal-title":"Pediatr. Radiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1002\/ca.20589","article-title":"Anomalous middle colic artery originating from common hepatic arery: A case report","volume":"21","author":"Wadhwa","year":"2008","journal-title":"Clin. Anat."},{"key":"ref_11","first-page":"363","article-title":"The middle colic artery originating from the coeliac trunk","volume":"63","author":"Yildirim","year":"2004","journal-title":"Folia Morphol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s12565-017-0401-2","article-title":"Anomalous inferior mesenteric artery supplying the ascending, transverse, descending, and sigmoid colons","volume":"93","author":"Abe","year":"2018","journal-title":"Anat. Sci. Int."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s00276-012-0987-y","article-title":"A middle mesenteric artery","volume":"34","author":"Milnerowicz","year":"2012","journal-title":"Surg. Radiol. Anat."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/BF01627894","article-title":"Middle mesenteric artery: An anomalous origin of a middle colic artery","volume":"15","author":"Yoshida","year":"1993","journal-title":"Surg. Radiol. Anat."},{"key":"ref_15","unstructured":"Quain, R. (1844). The Anatomy of the Arteries of the Human Body and Its Applications to Pathology and Operative Surgery, Taylor and Walton."},{"key":"ref_16","unstructured":"Adachi, B. (1928). Das Arteriensystem der Japaner, Maruzen."},{"key":"ref_17","first-page":"564","article-title":"Beitrag zu den Variationen der Oberbaucharterien","volume":"64","author":"Scharizer","year":"1952","journal-title":"Wien. Klin. Wochenschr."},{"key":"ref_18","unstructured":"Haller, A.V. (1747). Iconum Anatomicarum Partium Corporis Humani. Fasc. 3, Vandenhoeck."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00000658-191702000-00006","article-title":"A composite study of the coeliac axis artery","volume":"65","author":"Lipshutz","year":"1917","journal-title":"Ann. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.aanat.2013.06.003","article-title":"Variations in the anatomy of the celiac trunk: A systematic review and clinical implications","volume":"195","author":"Panagouli","year":"2013","journal-title":"Ann. Anat."},{"key":"ref_21","unstructured":"Henle, J. (1868). Handbuch der Gef\u00e4sslehre des Menschen. Handbuch der Systematischen Anatomie des Menschen, Friedrich Vieweg und Sohn."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF02300762","article-title":"\u00dcber die Variet\u00e4ten der Arteria coeliaca und deren Entwicklung","volume":"25","author":"Tandler","year":"1904","journal-title":"Anatomische Hefte"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00276-012-0989-9","article-title":"Absence of the celiac trunk: Case report using MDCT angiography","volume":"34","author":"Matusz","year":"2012","journal-title":"Surg. Radiol. Anat."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0940-9602(11)80141-X","article-title":"A rare case of absence of the celiac trunk: The left gastric, the splenic, the common hepatic and the superior mesenteric arteries arising independently from the abdominal aorta","volume":"177","author":"Yamaki","year":"1995","journal-title":"Ann. Anat."},{"key":"ref_25","first-page":"185","article-title":"\u00dcber eine Anastomose zwischen den St\u00e4mmen der Art. coeliaca und der Art. mesenterica superior","volume":"32","year":"1904","journal-title":"Gegenbaurs Morphol. Jahrb."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/BF02118337","article-title":"Untersuchungen \u00fcber den anastomotischen Kanal zwischen der Arteria coeliaca und mesenterica superior und damit in Zusammenhang stehende Fragen","volume":"107","author":"Schlyvitch","year":"1937","journal-title":"Z. Anat. Entwicklungsgesch."},{"key":"ref_27","first-page":"427","article-title":"\u00dcber eine Anastomose zwischen dem Truncus coeliacus, der Arteria mesenterica superior und der Arteria mesenterica inferior mit anderen Variet\u00e4ten der unpaarigen und paarigen \u00c4ste der Bauchaorta bei einem Individuum","volume":"119","author":"Zwerina","year":"1966","journal-title":"Anat. Anz."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.aanat.2005.02.011","article-title":"A rare variation of the coeliac trunk","volume":"187","author":"Uysal","year":"2005","journal-title":"Ann. Anat."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.aanat.2006.11.013","article-title":"A common celiacomesenteric trunk, and a brief review of the literature","volume":"189","author":"Yi","year":"2007","journal-title":"Ann. Anat."},{"key":"ref_30","first-page":"217","article-title":"Hepato-gastric and spleno-mesenteric arterial trunks: Anatomical variation report and review of literature","volume":"118","author":"Mariani","year":"2013","journal-title":"Ital. J. Anat. Embryol."},{"key":"ref_31","first-page":"385","article-title":"Zur Morphologie der Mesenterialbildungen am Darmkanal der Wirbelthiere. I. Theil. Amphibien und Reptilien","volume":"18","author":"Klaatsch","year":"1892","journal-title":"Gegenbaurs Morphol. Jahrb."},{"key":"ref_32","first-page":"609","article-title":"Zur Morphologie der Mesenterialbildungen am Darmkanal der Wirbelthiere. II. Theil. S\u00e4ugethiere","volume":"18","author":"Klaatsch","year":"1892","journal-title":"Gegenbaurs Morphol. Jahrb."},{"key":"ref_33","first-page":"639","article-title":"\u00dcber die Entwicklung, Wanderung und Variation der Bauchaortenzweige bei den Wirbeltieren","volume":"16","author":"Broman","year":"1908","journal-title":"Ergeb. Anat. Entwicklungsgesch."},{"key":"ref_34","unstructured":"Keibel, F., and Mall, F.P. (1912). The development of the blood, the vascular system, and the spleen. Manual of Human Embryology, Lippincott."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/BF02593640","article-title":"Die Entwicklung der Form des Magendarmkanales beim Menschen","volume":"64","author":"Pernkopf","year":"1922","journal-title":"Z. Anat. Entwicklungsgesch."},{"key":"ref_36","unstructured":"O\u2019Rahilly, R., and M\u00fcller, F. (1996). Human Embryology & Teratology, Wiley-Liss. [2nd ed.]."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/BF02109984","article-title":"Zur Entwickelungsgeschichte der menschlichen Darmarterien","volume":"23","author":"Tandler","year":"1903","journal-title":"Anatomische Hefte"},{"key":"ref_38","first-page":"1403","article-title":"Morphological variability of arterial sources of the renal polar parenchyma and its clinical importance","volume":"56","author":"Zahoi","year":"2015","journal-title":"Rom. J. Morphol. Embryol."},{"key":"ref_39","unstructured":"Haller, A.V. (1749). Iconum Anatomicarum Partium Corporis Humani. Fasc. 4, Vandenhoeck."},{"key":"ref_40","first-page":"563","article-title":"Das Arteriensystem","volume":"Volume 6","author":"Bolk","year":"1933","journal-title":"Handbuch der Vergleichenden Anatomie der Wirbeltiere"},{"key":"ref_41","unstructured":"Ellenberger, W., and Baum, H. (1926). Handbuch der vergleichenden Anatomie der Haustiere, Springer. [16th ed.]."},{"key":"ref_42","first-page":"136","article-title":"Variations pertaining to the aortic arches and their branches; with comments on surgically important types","volume":"31","author":"Liechty","year":"1957","journal-title":"Q. Bull. Northwest Univ. Med. Sch."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00276-016-1796-5","article-title":"The aberrant right subclavian artery: Cadaveric study and literature review","volume":"39","author":"Natsis","year":"2017","journal-title":"Surg. Radiol. Anat."},{"key":"ref_44","first-page":"229","article-title":"Arterial anomalies pertaining to the aortic arches and the branches arising from them","volume":"16","author":"Poynter","year":"1916","journal-title":"Univ. Stud. Univ. Nebraska"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.surg.2015.12.021","article-title":"The nonrecurrent laryngeal nerve: A clinical anatomic mapping with regard to intraoperative neuromonitoring","volume":"160","author":"Konschake","year":"2016","journal-title":"Surgery"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/ahe.12202","article-title":"Bicarotid Trunk in the Domestic Cat","volume":"45","author":"More","year":"2016","journal-title":"Anat. Histol. Embryol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Dauber, W. (2007). Pocket atlas of Human Anatomy Founded by Heinz Feneis, Thieme. [5th ed.].","DOI":"10.1055\/b-005-148848"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/BF00305554","article-title":"The human thyrocervical trunk: Configuration and variability reinvestigated","volume":"163","author":"Lischka","year":"1982","journal-title":"Anat. Embryol."},{"key":"ref_49","first-page":"1","article-title":"Zur vergleichenden Anatomie der Kopfarterien bei den Mammalia","volume":"67","author":"Tandler","year":"1898","journal-title":"Denkschr. Kaiser. Akad. Wiss."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Lasjaunias, P., and Berenstein, A. (1987). Surgical Neuroangiography. Vol. 1 Functional Anatomy of craniofacial Arteries, Springer.","DOI":"10.1007\/978-3-642-71185-5_1"},{"key":"ref_51","first-page":"47","article-title":"Transformation of the aortic arc system during the development of the human embryo","volume":"68","author":"Congdon","year":"1922","journal-title":"Contrib. Embryol."},{"key":"ref_52","first-page":"696","article-title":"Entwickelungsgeschichte des Gef\u00e4sssystems","volume":"1","author":"Hochstetter","year":"1891","journal-title":"Ergeb. Anat. Entwicklungsgesch."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10029-015-1444-8","article-title":"Corona mortis: In vivo anatomical knowledge and the risk of injury in totally extraperitoneal inguinal hernia repair","volume":"20","author":"Ates","year":"2016","journal-title":"Hernia"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/9\/449\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:06:50Z","timestamp":1760177210000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/56\/9\/449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,4]]},"references-count":53,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,9]]}},"alternative-id":["medicina56090449"],"URL":"https:\/\/doi.org\/10.3390\/medicina56090449","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,4]]}}}