{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:49:53Z","timestamp":1760233793180,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Pregnancy and the postpartum period represent a condition characterized by a thrombotic predisposition. The majority of pregnant women do not face acute or severe thrombotic events. In general, mild inconveniences such as leg swelling or moderately painful thrombotic events (phlebitis) are encountered. However, when pregnancy is associated with inherited or acquired deficits that affect homeostasis, the risk of acute or even life-threatening events can increase significantly. The major consequence is the loss of the fetus or the venous thromboembolism that endangers the mother\u2019s life. Venous thromboembolism is caused by deep vein thrombosis, therefore timely detection and especially the assessment of the extent of the thrombotic event are crucial. In this paper we have summarized the most important paraclinical investigations. The study emphasizes the importance of selecting the methods of investigation. The right choice allows establishing a correct diagnosis and individualizing the treatment.<\/jats:p>","DOI":"10.3390\/medicina57020160","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T16:12:10Z","timestamp":1613146330000},"page":"160","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Serological Parameters and Vascular Investigation for a Better Assessment in DVT during Pregnancy\u2014A Systematic Review"],"prefix":"10.3390","volume":"57","author":[{"given":"Catalina","family":"Filip","sequence":"first","affiliation":[{"name":"Saint Spiridon University Hospital, Vascular Surgery Clinic, Independence Boulevard no. 1, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetra Gabriela","family":"Socolov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Albu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiana","family":"Filip","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana","family":"Serban","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu Florin","family":"Popa","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S309","DOI":"10.21037\/cdt.2017.10.08","article-title":"Deep venous thrombosis in pregnancy: Incidence, pathogenesis and endovascular management","volume":"7","author":"Devis","year":"2017","journal-title":"Cardivasc. Diagn. Ther."},{"key":"ref_2","first-page":"394","article-title":"Acute deep vein thrombosis (DVT); Evolving treatment strategies and endovascular therapy","volume":"92","author":"Conklin","year":"2009","journal-title":"Rhode Isl. Med. 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