{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:10:19Z","timestamp":1790129419987,"version":"4.0.1"},"reference-count":41,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T00:00:00Z","timestamp":1614816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: The potential role of lung ultrasound (LUS) in characterizing lung involvement in Coronavirus disease 2019 (COVID-19) is still debated. The aim of the study was to estimate sensitivity of admission LUS for the detection of SARS-CoV-2 lung involvement using Chest-CT (Computed Tomography) as reference standard in order to assess LUS usefulness in ruling out COVID-19 pneumonia in the Emergency Department (ED). Methods: Eighty-two patients with confirmed COVID-19 and signs of lung involvement on Chest-CT were consecutively admitted to our hospital and recruited in the study. Chest-CT and LUS examination were concurrently performed within the first 6\u201312h from admission. Sensitivity of LUS was calculated using CT findings as a reference standard. Results: Global LUS sensitivity in detecting COVID-19 pulmonary lesions was 52%. LUS sensitivity ranged from 8% in case of focal and sporadic ground-glass opacities (mild disease), to 52% for a crazy-paving pattern (moderate disease) and up to 100% in case of extensive subpleural consolidations (severe disease), although LUS was not always able to detect all the consolidations assessed at Chest-CT. LUS sensitivity was higher in detecting a typical Chest-CT pattern (60%) and abnormalities showing a middle-lower zone predominance (79%). Conclusions: As admission LUS may result falsely negative in most cases, it should not be considered as a reliable imaging tool in ruling out COVID-19 pneumonia in patients presenting in ED. It may at least represent an expanded clinical evaluation that needs integration with other diagnostic tests (e.g., nasopharyngeal swab, Chest-CT).<\/jats:p>","DOI":"10.3390\/medicina57030236","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T21:58:07Z","timestamp":1614895087000},"page":"236","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Low Sensitivity of Admission Lung US Compared to Chest CT for Diagnosis of Lung Involvement in a Cohort of 82 Patients with COVID-19 Pneumonia"],"prefix":"10.3390","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-7403","authenticated-orcid":false,"given":"Carla Maria Irene","family":"Quarato","sequence":"first","affiliation":[{"name":"COVID-19 Center, Policlinico \u201cRiuniti\u201d di Foggia, Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, 71100 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3932-3803","authenticated-orcid":false,"given":"Antonio","family":"Mirijello","sequence":"additional","affiliation":[{"name":"COVID-19 Unit, Department of Medical Sciences, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donato","family":"Lacedonia","sequence":"additional","affiliation":[{"name":"COVID-19 Center, Policlinico \u201cRiuniti\u201d di Foggia, Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, 71100 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Russo","sequence":"additional","affiliation":[{"name":"COVID-19 Center, Intensive Care Unit, Department of Emergency Medicine and Critical Care, IRCCS Fondazione Casa Sollievo Della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Maria","family":"Maggi","sequence":"additional","affiliation":[{"name":"COVID-19 Center, Emergency Medicine Unit, Department of Emergency Medicine and Critical Care, IRCCS Fondazione Casa Sollievo Della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Rea","sequence":"additional","affiliation":[{"name":"Department of Radiology, \u201cVincenzo Monaldi\u201d Hospital\u2014AORN Ospedale Dei Colli, 80100 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Simeone","sequence":"additional","affiliation":[{"name":"Department of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Borelli","sequence":"additional","affiliation":[{"name":"Department of Radiology, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Feragalli","sequence":"additional","affiliation":[{"name":"Oral and Biotechnological Sciences\u2014Radiology Unit \u201cG. D\u2019Annunzio\u201d, Department of Medical, University of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2667-077X","authenticated-orcid":false,"given":"Giulia","family":"Scioscia","sequence":"additional","affiliation":[{"name":"COVID-19 Center, Policlinico \u201cRiuniti\u201d di Foggia, Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, 71100 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9939-2697","authenticated-orcid":false,"given":"Maria Pia Foschino","family":"Barbaro","sequence":"additional","affiliation":[{"name":"COVID-19 Center, Policlinico \u201cRiuniti\u201d di Foggia, Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, 71100 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Massa","sequence":"additional","affiliation":[{"name":"Geriatric and COVID-19 Unit, Department of Medical Sciences, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"De Cosmo","sequence":"additional","affiliation":[{"name":"COVID-19 Unit, Department of Medical Sciences, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6685-6942","authenticated-orcid":false,"given":"Marco","family":"Sperandeo","sequence":"additional","affiliation":[{"name":"Unit of Interventional and Diagnostic Ultrasound of Internal Medicine, Department of Medical Sciences, IRCCS Fondazione Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,4]]},"reference":[{"key":"ref_1","unstructured":"WHO (2020, May 30). 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